Results 1 to 10 of about 2,758,303 (304)

Prevalence of Gene Rearrangement by Multiplex PCR in De Novo Acute Myeloid Leukemia in Adult Iraqi Patients

open access: yesJournal of Blood Medicine, 2023
Ali AlJabban, Jaffar Alalsaidissa Department of Pathology, College of Medicine, University of Baghdad, Baghdad, IraqCorrespondence: Ali AlJabban, Department of Pathology, College of medicine, University of Baghdad, Baghdad, Iraq, Tel +9647706056226 ...
AlJabban A, Alalsaidissa J
doaj   +1 more source

ERG rearrangement is associated with prostate cancer-related death in Chinese prostate cancer patients.

open access: yesPLoS ONE, 2014
Recently, ETS-related gene (ERG) gene rearrangements, phosphatase tensin homologue (PTEN) deletions and EGFR family aberrations were characterized as potential biomarkers for prostate cancer (PCa) patient management.
Mei Qi   +10 more
doaj   +1 more source

Marfan syndrome with a complex chromosomal rearrangement including deletion of the FBN1 gene

open access: yesMolecular Cytogenetics, 2012
Background The majority of Marfan syndrome (MFS) cases is caused by mutations in the fibrillin-1 gene (FBN1), mapped to chromosome 15q21.1. Only few reports on deletions including the whole FBN1 gene, detected by molecular cytogenetic techniques, were ...
Colovati Mileny ES   +8 more
doaj   +1 more source

T cell factor-1 controls the lifetime of CD4+ CD8+ thymocytes in vivo and distal T cell receptor α-chain rearrangement required for NKT cell development. [PDF]

open access: yesPLoS ONE, 2014
Natural killer T (NKT) cells are a component of innate and adaptive immune systems implicated in immune, autoimmune responses and in the control of obesity and cancer.
Archna Sharma   +2 more
doaj   +1 more source

Anaplastic lymphoma kinase-positive pulmonary inflammatory myofibroblastic tumor with sarcomatous morphology and distant metastases: An unusual histomorphology and behavior

open access: yesIndian Journal of Pathology and Microbiology, 2015
Inflammatory myofibroblastic tumor (IMT), an intermediate-grade neoplasm of myofibroblastic/fibroblastic differentiation, occurs commonly in children and young adults.
Bhawna Sethi   +3 more
doaj   +1 more source

The reverse TRBV30 gene of mammals: a defect or superiority in evolution?

open access: yesBMC Genomics
At the 3’ end of the C2 gene in the mammalian TRB locus, a distinct reverse TRBV30 gene (named TRBV31 in mice) has been conserved throughout evolution.
Fengli Wu   +7 more
doaj   +1 more source

Epigenetic Enhancer Marks and Transcription Factor Binding Influence Vκ Gene Rearrangement in Pre-B Cells and Pro-B Cells

open access: yesFrontiers in Immunology, 2018
To date there has not been a study directly comparing relative Igκ rearrangement frequencies obtained from genomic DNA (gDNA) and cDNA and since each approach has potential biases, this is an important issue to clarify.
Eden Kleiman   +2 more
doaj   +1 more source

The mitochondrial genome of a social aphid, Pseudoregma bambucicola (Hemiptera: Aphididae: Hormaphidinae)

open access: yesMitochondrial DNA. Part B. Resources, 2019
In this study, the complete mitochondrial genome of the social aphid Pseudoregma bambucicola was assembled and annotated. The genome spans 16,631 bp in length with a high A + T content (85.1%), containing 13 protein-coding genes, 22 tRNA genes, two rRNA ...
Hui Zhang   +3 more
doaj   +1 more source

Detection of t(8;14) c-myc/IgH gene rearrangement by long-distance polymerase chain reaction in patients with diffuse large B-cell lymphoma

open access: yesHematology/Oncology and Stem Cell Therapy, 2016
Objective/background: Specific chromosomal translocations are found in human leukemias and lymphomas. These translocations are closely related to particular histological and immunological phenotypes. In Burkitt's lymphoma, translocation t(8;14)(q24;q32),
Arezoo Kiaei   +5 more
doaj   +1 more source

Annotation of gene loci and analysis of expression diversity in sheep immunoglobulin

open access: yesFrontiers in Immunology
As an important livestock species, sheep exhibit remarkable environmental adaptability. Immunoglobulins, expressed by B cells, are among the most crucial effector molecules in adaptive immunity.
Mingli Wu   +5 more
doaj   +1 more source

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