Results 1 to 10 of about 264,764 (308)
Insects, 2022 Gene rearrangement of the mitochondrial genome of insects, especially the rearrangement of protein-coding genes, has long been a hot topic for entomologists.
Xinyu Ge +6 more
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Rearranging Detection of Gene Rearrangements [PDF]
Journal of Thoracic Oncology, 2015 ®ecent years have witnessed a dramatic expansion in our knowledge of the genetic diversity of non–small-cell lung cancer (NSCLC), and in particular adenocarcinoma. This appreciation of the genetic landscape of the disease has resulted in the development of targeted therapies that are directed to ward activated oncogenes.
Davies, Kurtis D. +2 more
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Insects, 2022 Extensive gene rearrangement is characteristic in the mitogenomes of thrips (Thysanoptera), but the historical process giving rise to the contemporary gene rearrangement pattern remains unclear.
Qiaoqiao Liu +5 more
doaj +1 more source
Frontiers in Immunology, 2023 Pure red-cell aplasia (PRCA) is a syndrome associated with reduced erythroid precursors. This report presents the case of an elderly PRCA patient with significantly proliferated γδT cells and clonal T-cell receptor (TCR) gene rearrangement.
Xian Li +3 more
doaj +1 more source
Lateral gene transfer, rearrangement, reconciliation [PDF]
BMC Bioinformatics, 2013 Models of ancestral gene order reconstruction have progressively integrated different evolutionary patterns and processes such as unequal gene content, gene duplications, and implicitly sequence evolution via reconciled gene trees. These models have so far ignored lateral gene transfer, even though in unicellular organisms it can have an important ...
Patterson, Murray +3 more
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Prevalence of Gene Rearrangement by Multiplex PCR in De Novo Acute Myeloid Leukemia in Adult Iraqi Patients. [PDF]
J Blood Med, 2023 Ali AlJabban, Jaffar Alalsaidissa Department of Pathology, College of Medicine, University of Baghdad, Baghdad, IraqCorrespondence: Ali AlJabban, Department of Pathology, College of medicine, University of Baghdad, Baghdad, Iraq, Tel +9647706056226 ...
AlJabban A, Alalsaidissa J.
europepmc +2 more sources
Immunoglobulin λ Gene Rearrangement Can Precede κ Gene Rearrangement [PDF]
Journal of Immunology Research, 1989 Immunoglobulin genes are generated during differentiation of B lymphocytes by joining gene segments. A mouse pre‐B cell contains a functional immunoglobulin heavy‐chain gene, but no light‐chain gene. Although there is only one heavy‐chain locus, there are two lightchain loci: κ and λ.It has been reported that κ loci in the germ‐line configuration are ...
Berg, Jörg +3 more
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Lack of ROS1 Gene Rearrangement in Glioblastoma Multiforme. [PDF]
PLoS ONE, 2015 Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor, and the prognosis remains poor. Rearrangement of ROS1 gene, which was shown to have an oncogenic potential, was previously discovered in GBM cell lines.
Sun Min Lim +8 more
doaj +1 more source
Frontiers in Immunology, 2021 Multiple gene-driven programmed cell death 1 ligand 1 (PD-L1)-expressing non-small-cell lung cancer (NSCLC) is very rare. Previous studies have shown that patients with NSCLC with anaplastic lymphoma kinase (ALK) gene rearrangement rarely benefit from PD-
Wen Dong +4 more
doaj +1 more source
Gene rearrangements in bone marrow cells of patients with acute myelogenous leukemia [PDF]
, 2000 At diagnosis, clonal gene rearrangement probes {[}retinoic acid receptor (RAR)-alpha, major breakpoint cluster region (M-bcr), immunoglobulin (Ig)-JH, T cell receptor (TcR)-beta, myeloid lymphoid leukemia (MLL) or cytokine genes (GM-CSF, G-CSF, IL-3 ...
Braun, S. +5 more
core +1 more source