Results 11 to 20 of about 159,072 (309)

Prevalence of Gene Rearrangement by Multiplex PCR in De Novo Acute Myeloid Leukemia in Adult Iraqi Patients. [PDF]

J Blood Med, 2023
Ali AlJabban, Jaffar Alalsaidissa Department of Pathology, College of Medicine, University of Baghdad, Baghdad, IraqCorrespondence: Ali AlJabban, Department of Pathology, College of medicine, University of Baghdad, Baghdad, Iraq, Tel +9647706056226 ...
AlJabban A, Alalsaidissa J.
europepmc   +3 more sources

Comparative Mitogenomic Analyses of Hydropsychidae Revealing the Novel Rearrangement of Protein-Coding Gene and tRNA (Trichoptera: Annulipalpia)

Insects, 2022
Gene rearrangement of the mitochondrial genome of insects, especially the rearrangement of protein-coding genes, has long been a hot topic for entomologists.
Xinyu Ge, Haoming Zang, Lang Peng
exaly   +3 more sources

Gene conversion in human rearranged immunoglobulin genes [PDF]

Immunogenetics, 2006
Over the past 20 years, many DNA sequences have been published suggesting that all or part of the V_H segment of a rearranged immunoglobulin gene may be replaced in vivo. Two different mechanisms appear to be operating. One of these
Darlow, J.M., John M. Darlow, David I. Stott, Stott, D.I.   +3 more
core   +3 more sources

Lack of ROS1 Gene Rearrangement in Glioblastoma Multiforme. [PDF]

PLoS ONE, 2015
Glioblastoma multiforme (GBM) is the most aggressive type of brain tumor, and the prognosis remains poor. Rearrangement of ROS1 gene, which was shown to have an oncogenic potential, was previously discovered in GBM cell lines.
Sun Min Lim, Frank Policht, Jong Hee Chang, Frank Policht (795308), Se Hoon Kim (138763), Junjeong Choi, Sun Min Lim (603669), Junjeong Choi (795304), John Schulz, Jinyoung Sohn, Byoung Chul Cho, John Schulz (795309), Kristine Jacobson, Jong Hee Chang (795305), Byoung Chul Cho (41005), Kristine Jacobson (795307), Se Hoon Kim, Jinyoung Sohn (795306)   +17 more
core   +4 more sources

Case Report: Experience of a rare case of primary acute mast cell leukemia with FGFR1 gene rearrangement. [PDF]

Front Oncol
Mast cell leukemia represents the most malignant subtype of systemic mastocytosis, characterized by a dire clinical prognosis. Currently, no standard treatment regimen exists, with allogeneic hematopoietic stem cell transplantation being the sole option ...
Liu Y, Gao S, Du H, Ji H, Li Z.
europepmc   +2 more sources

Maternal acute lymphoctic leukemia with rearrangement of the mixed lineage leukemia gene occurring during pregnancy

Hematology/Oncology and Stem Cell Therapy, 2009
Acute lymphoblastic leukemia (ALL) is a relatively rare disease during pregnancy, accounting for about 15% of all cases of pregnancy-associated leukemia.
Ahmed, Syed Osman, Claudia Walter, Amr Nassar, Naeem Chaudhri, Almhareb, Fahed, Alzahrani, Hazzaa, Hazzaa Alzahrani, Aljurf, Mahmoud, Nassar, Amr, Fahed Almhareb, Abu Jafar Saleh, Bakr, Mohammad, Chaudhri, Naeem, Mahmoud Aljurf, Syed Osman Ahmed, Mohammad Bakr, Walter, Claudia, Saleh, Abu Jafar   +17 more
core   +2 more sources

Marfan syndrome with a complex chromosomal rearrangement including deletion of the FBN1 gene

Molecular Cytogenetics, 2012
Background The majority of Marfan syndrome (MFS) cases is caused by mutations in the fibrillin-1 gene (FBN1), mapped to chromosome 15q21.1. Only few reports on deletions including the whole FBN1 gene, detected by molecular cytogenetic techniques, were ...
Luciana RJ da Silva, Silva, Luciana R. J. da [UNIFESP], Guilherme, Roberta S. [UNIFESP], Takeno Sylvia S, Tatiane I Mancini, Colovati Mileny ES, Mello, Claudia B. de [UNIFESP], Dutra, Ana R. N. [UNIFESP], Guilherme Roberta S, A Perez Ana B, N Dutra Ana R, de Mello Cláudia B, Melaragno Maria I, Perez, Ana B. A. [UNIFESP], Melaragno, Maria I. [UNIFESP], Ana B A Perez, Mancini, Tatiane I. [UNIFESP], Colovati, Mileny E. S. [UNIFESP], Ana R N Dutra, Mancini Tatiane I, Sylvia S Takeno, da Silva Luciana RJ, Mileny ES Colovati, Takeno, Sylvia S. [UNIFESP], Maria I Melaragno, Cláudia B de Mello, Roberta S Guilherme   +26 more
core   +2 more sources

Ki67 deficiency impedes chromatin accessibility and BCR gene rearrangement. [PDF]

J Exp Med
The proliferation marker Ki67 has been attributed critical functions in maintaining mitotic chromosome morphology and heterochromatin organization during the cell cycle, indicating a potential role in developmental processes requiring rigid cell-cycle ...
Ding Z, Hagan M, Yan F, Schroer NWY, Polmear J, Good-Jacobson KL, Dvorscek AR, Pitt C, O'Donnell K, Nutt SL, Zotos D, McKenzie C, Hill DL, Robinson MJ, Quast I, Koentgen F, Tarlinton DM.   +16 more
europepmc   +2 more sources

Rearranging Detection of Gene Rearrangements [PDF]

Journal of Thoracic Oncology, 2015
®ecent years have witnessed a dramatic expansion in our knowledge of the genetic diversity of non–small-cell lung cancer (NSCLC), and in particular adenocarcinoma. This appreciation of the genetic landscape of the disease has resulted in the development of targeted therapies that are directed to ward activated oncogenes.
Davies, Kurtis D., Doebele, Robert C., Aisner, Dara L.   +2 more
openaire   +2 more sources

Positive Correlation of the Gene Rearrangements and Evolutionary Rates in the Mitochondrial Genomes of Thrips (Insecta: Thysanoptera)

Insects, 2022
Extensive gene rearrangement is characteristic in the mitogenomes of thrips (Thysanoptera), but the historical process giving rise to the contemporary gene rearrangement pattern remains unclear.
Qiaoqiao Liu, Jia He, Fan Song, Li Tian, Wanzhi Cai, Hu Li   +5 more
doaj   +1 more source