Results 301 to 310 of about 1,115,297 (399)

T‐2 Toxin Exploits Gut‐Derived Staphylococcus Saprophyticus to Disrupt Hepatic Macrophage Homeostasis

Advanced Science, EarlyView.
T‐2 toxin promotes the proliferation of intestinal S. saprophyticus and facilitates its translocation to the liver in piglets and mice. The translocated bacteria trigger autophagy in Kupffer cells and recruit monocytes to the liver through the nucleotide‐binding oligomerization domain 2 (NOD2) signaling pathway, alongside the M1 polarization of hepatic
Yuanyuan Zhu, Liu Xu, Fangrui Guo, Jianyu Qu, Xiangyan Liu, Qiurong Xu, Jie Sheng, Jiangping Wang, Xiaohong Xie, Ruimin Ren, Chuan Zhou, Sisi Yan, Shuiping Liu, Zhihang Yuan, Rongfang Li, Jing Wu, Jine Yi, Yulong Yin, Lixin Wen, Ji Wang   +19 more
wiley   +1 more source

Sex-Specific Associations of Serum Alkaline Phosphatase With Metabolic Syndrome and Its Components: Over 15 Years of Follow-Up Among Iranian Adults. [PDF]

J Clin Lab Anal
Hadaegh P, Abdi A, Hasheminia M, Hadaegh F, Azizi F, Tohidi M.   +5 more
europepmc   +1 more source

Arid1a Deficiency Drives Aristolochic Acid‐Induced Liver Tumorigenesis through Ctnnb1 Mutation and Defective Nucleotide Excision Repair

Advanced Science, EarlyView.
ARID1A is frequently mutated in both non‐malignant tissues and cancers, but its role in tumor development after exposure to genotoxic carcinogen remains unclear. It is found that aristolochic acid I accelerated liver tumorigenesis in ARID1A‐deficient context by impairing nucleotide excision repair and enhancing carcinogen bioactivation, revealing key ...
Lan Wang, Shi‐Hao Bai, Shu‐Jin Song, Xiao‐Li Zhang, Xue‐Ying Shang, Zhao‐Ning Lu, Xiao‐Fang Cui, Xin‐Le Zhu, Ze‐Guang Han   +8 more
wiley   +1 more source

Comparison of Salivary Alkaline Phosphatase Activity and Cervical Vertebral Maturation Stages as Indicators for Skeletal Maturity.

J Pharm Bioallied Sci
Panat U, Sodawala J, Shukla S, Tayade C, Thakur VJ, Belchandan A.   +5 more
europepmc   +1 more source

Continuous Spectrophotometric Measurement of Serum Alkaline Phosphatase Activity

, 1967
G N Bowers, Mari-Lou Kelley, R B McComb
openalex   +1 more source

Electrosensitive Heterogeneous Short Fibers via Acousto‐Electric Coupling for Sequential Bone Regeneration in Infectious Defects

Advanced Science, EarlyView.
Electrosensitive heterogeneous short fibers can accurately respond to ultrasonic field regulation through the synergistic interaction of piezoelectric and conductive dual elements. At an ultrasound intensity of 1.5 W cm−2, it can effectively activate bacterial peroxisome and necrotic apoptotic pathway and promote bacterial apoptosis.
Xiaoyu Han, Fan Wang, Pengcheng Xiao, Zheng Yang, Mingyue Liu, Zeyu Han, Zijie Wang, Anan Jiang, Jindong Tan, Juan Wang, Wenguo Cui, Dingqun Bai   +11 more
wiley   +1 more source

The Relationship Between Alkaline Phosphatase and Periodontitis: The Mediating Role of Cranial Bone Mineral Density. [PDF]

Int Dent J
Tang Q, Yang M, Xiao Q, Cheng C.
europepmc   +1 more source

Self‐Trapped Excitons in Carbon Quantum Dots with Large NIR‐II Photo‐Thermoelectric Catalysis Induce Pyroptosis for Cancer Therapy

Advanced Science, EarlyView.
The self‐trapped excitons in carbon quantum dots can serve as NIR‐II absorbers, which efficiently induce pyroptosis by driving the generation of reactive oxygen species through mild NIR‐II photothermal effect. Combined with local photophysical therapy and the cascade reaction of pyroptosis, it can activate systemic immunity and prevent tumor recurrence.
Tesen Zhang, Qingcheng Wang, Quansheng Cheng, Han Wang, He Feng, Hui Zhang, Mengbo Lin, Feili Cai, Zheng Fang, Ruo Wang, Gang Chen   +10 more
wiley   +1 more source

ZMYM2 inhibits NANOG-mediated reprogramming [version 1; peer review: 2 approved, 1 approved with reservations] [PDF]

, 2019
Adams, David J, Lawrence, Moyra, Lombard, Patrick, Silva, Jose C.R., Theunissen, Thorold W   +4 more
core   +1 more source

AP2M1 Amplification Orchestrates Notch‐Mediated Chemoresistance in Hematopoietic Stem Cells of Acute Myeloid Leukemia Patients

Advanced Science, EarlyView.
The precise regulation of AP2M1 is essential for normal hematopoiesis. Overexpression of AP2M1 negatively affects the clinical outcomes of AML patients. Upregulation of AP2M1 enhances stemness and chemoresistance in HSPC cells of AML. AP2M1 modulates NOTCH1 expression, enhancing the Notch1 signaling pathway.
Hansong Lee, Eun Kyoung Kim, Hee Young Ju, Chae Rin Lee, Soyul Ahn, Eun‐Sun Kim, Kyungjae Myung, Won Kyu Kim, Su‐Yeon Cho, Yujin Kwon, Dokyoung Kim, Yeuni Yu, Eun Jung Kwon, Hyomin Kim, Seong Ik Mun, Dong Min Lim, Kihun Kim, Hye Jin Heo, Seung Eun Baek, Sun Young Lee, Hyunsoo Cho, Eun Young Choi, Tae Sik Goh, Ninib Baryawno, Dongjun Lee, Ki Sun Jung, Keon Hee Yoo, Chang‐Kyu Oh, Yun Hak Kim   +28 more
wiley   +1 more source