Results 311 to 320 of about 516,488 (356)

Alkaline phosphatase in mitochondria

Cell Biology International Reports, 1977
In electron microscope cytochemical studies alkaline phosphatase activity was present in the mitochondria of all liver cells and associated with the plasma membrane of the cells of bile canaliculi. The mitochondrial activity was partially inhibited by L-phenylalanine and Levamisole but the plasma membrane associated activity was completely inhibited by
L.M. Franks, Frances Benham, D.C. Cottell, Patricia D. Wilson   +3 more
openaire   +3 more sources

Structure of alkaline phosphatases

Clinica Chimica Acta, 1990
The crystal structure of alkaline phosphatase (AP) from Escherichia coli, which is a prototype for mammalian APs, has been refined to a crystallographic R-factor of 0.184 at 2.0 A resolution. During the course of the refinement residues 380 to 410 were retraced and 190 to 200 were shifted by one residue, and substantial changes in the active site of ...
Harold W. Wyckoff, Eunice E. Kim
openaire   +2 more sources

The alkaline phosphatase anti‐alkaline phosphatase technique in dermatopathology

Journal of Cutaneous Pathology, 1987
The APAAP technique is an unlabelled antibody bridge technique which can be used on either frozen or paraffinembedded sections. One applies first a monoclonal antibody, then a polyclonal bridge antibody, and finally a soluble complex of alkaline phosphatase and monoclonal mouse anti‐alkaline phosphatase. Subsequently, the enzyme label is developed with
openaire   +2 more sources

Alkaline Phosphatase Isoenzymes

CRC Critical Reviews in Clinical Laboratory Sciences, 1979
At the time of admission, 4 to 8% of all hospital admissions have a elevation of alkaline phosphatase. This high incidence of alkaline phosphatasemia has resulted in not only a need to identify the source of the elevated alkaline phosphatase; it has also led to a marked proliferation in laboratory procedures aimed at identifying the various isoenzymes ...
Russell O. Bricre, John G. Batsakis
openaire   +2 more sources

Alkaline phosphatase in the thymus

Cells Tissues Organs, 1976
(1) Fetal thymuses, organs from patients who died from diseases that are not clinically known to be associated with concomitant lymphoid tissue involvement, as well as thymuses from patients dying from diseases which affect the lymphatic complex of the body, one way or another, have been investigated for their alkaline phosphatase activity, using ...
A.A. Tarkhan, M.T. Rakhawy, A.M. Zakaria
openaire   +3 more sources

Alkaline phosphatase in craniopharyngiomas

The Journal of Pathology, 1971
AbstractTHE derivation of the epithelium from which craniopharyngiomas arise is in doubt. Willis (1953) and Russell and Rubinstein (1959) state that these tumours are not distinguishable from “epitheliomas” in which squamous and basal cells are both present.
W. R. Timperley, S. Davies, P. Turner
openaire   +3 more sources

Alkaline Phosphatase in Schistosomiasis

Annals of Internal Medicine, 1971
Excerpt To the editor: In their interesting and very informative article on acute schistosomiasis mansoni (Ann Intern Med73:379-385, 1970) Dr.
openaire   +3 more sources

Thiophosphorylation of Alkaline Phosphatase

Nature New Biology, 1973
ALKALINE phosphatase from Escherichia coli has been reported to be phosphorylated by a phosphate ester substrate1, a particular feature being that only one of two potentially active sites appeared to be phosphorylated at any one time. Binding studies with inorganic phosphate have shown there is one high affinity and a second low affinity site at pH 8 ...
openaire   +3 more sources

Leukocyte alkaline phosphatase: Another organ‐specific alkaline phosphatase

American Journal of Hematology, 1983
AbstractWe have used enzyme specific inhibitors and heat inactivation to distinguish Leukocyte alkaline phosphate (LAP) from other organ‐specific alkaline phosphatases as well as to compare LAP from normal granulocytes and leukemic cells with elevated LAP.
Marcia K. Liepman, Donald M. Miller, Angela Yang   +2 more
openaire   +3 more sources

The Pancreas and Alkaline Phosphatase

Nature, 1946
IN various accounts of histochemical studies on the presence of alkaline phosphatase (substrate: sodium-β-glycerophosphate, pH. 9) in homologous organs, correspondences (for example, in kidney and intestine) have usually been stressed rather than differences.
openaire   +3 more sources