Results 251 to 260 of about 245,658 (306)

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Ascorbic Acid and Alkaline Phosphatase Activity

Enzyme, 2017
Ascorbic acid is found strikingly to decrease the activity of bovine kidney alkaline phosphatase in vitro. The inhibition of alkaline phosphatase is a function of ascorbic acid concentration and is time and temperature dependent. The presence of the substrate protects the enzyme against the inhibitory action of the vitamin.
Miggiano, Ga, Mordente, Alvaro, Martorana, Ge, Meucci, Elisabetta, Castelli, A.   +4 more
openaire   +4 more sources

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Phosphoprotein phosphatase activity of bovine intestinal alkaline phosphatase

Experientia, 1981
The phosphoprotein phosphatase activity of a commercial preparation of bovine intestinal alkaline phosphatase (EC 3.1.3.1) was examined using phosvitin and dentine phosphoprotein as substrates. Over 90% and 70% of the phosphorus from dentine phosphoprotein and phosvitin were hydrolyzed in 2 h.
B Y Hiraoka, K M Fukasawa, Harada M
exaly   +3 more sources

ALKALINE-PHOSPHATASE ACTIVITY OF POLYMORPHS IN MONGOLISM

Lancet, The, 1962
A G Baikie
exaly   +3 more sources

Alkaline phosphatase activity of the mouse

Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1984
Plasma alkaline phosphatase (PAP) activity of young adult CD mice is low (e.g. 1/10th of that of rat) and is lower in males than in females. The variability of PAP was assessed in groups of mice kept under different husbandry conditions (e.g. caging, diet, SPF). PAP activities of fed and fasted mice are similar.
C E, Pickering, R G, Pickering
openaire   +2 more sources

Inhibition of alkaline phosphatase activity by glucose

Clinica Chimica Acta, 1983
Non-enzymatic glycosylation (NEG) of alkaline phosphatase (AP) was studied after short- and long-term incubation with glucose and other carbohydrates. Glucose and amino sugars clearly inhibited the enzyme activity; this was in contrast to reducing and non-reducing disaccharides, which had an enhancing effect.
A, Pollak, H, Coradello, J, Leban, E, Maxa, M, Sternberg, K, Widhalm, G, Lubec   +6 more
openaire   +2 more sources

SERUM ALKALINE PHOSPHATASE ACTIVITY IN SHEEP

Australian Journal of Experimental Biology and Medical Science, 1974
SummaryThe influence of age and the R‐r‐i blood group system upon serum alkaline phosphatase activity is described.Changes in isoenzyme patterns of alkaline phosphatase activity, as determined by use of amino acid inhibitors and heat, were seen from birth to day 1 of life, with increasing age and between animals of the R and r blood group.
openaire   +2 more sources

Alkaline Phosphatase Activity in Immature Granulocytes

British Journal of Haematology, 1968
A positive reaction for alkaline phosphatase activity in granulocyte precursors (myelocytes, promyelocytes and even some blast cells) has been observed in three patients. Two of them had a blastic crisis of subacute or chronic myeloid leukaemia. In the third patient with a blastic crisis of a myeloproliferative syndrome, AP activity was unusually high ...
V, Malasková, J, Fuksová
openaire   +2 more sources

Studies on Alkaline Phosphatase

European Journal of Biochemistry, 1972
The three common homozygous variants of human placental alkaline phosphatase, types F1, S1 and I1 were partly purified and the concentration of active sites determined using a stopped‐flow procedure. A comparison of the variant steady‐state activities indicated that any differences in catalytic‐centre activity are marginal, both at alkaline pH (with 4 ...
D A, Byers, H N, Fernley, P G, Walker
openaire   +2 more sources