Results 161 to 170 of about 116,300 (262)

The transcriptomic and metabolomic mechanisms responsible for high medicinal quality in Dendrobium huoshanense under different cultivation techniques. [PDF]

BMC Plant Biol
Yi S, Chen C, Li G, Xu T, Song C, Huang X, Zhang M, Song X, Wang W, Guo L, Han B.   +10 more
europepmc   +1 more source

From Salt‐Affected Marginal Land Resource to Remediation Agent: Halophyte‐Derived Biochar for Ameliorating Cd‐Contaminated Acidic Soil

Land Degradation &Development, EarlyView.
ABSTRACT Cadmium (Cd) contamination of acidic soils poses a significant threat to ecosystem stability and crop health. This study evaluated the potential of biochar derived from the halophyte Salicornia europaea (SBC), a salt‐tolerant plant that grows on saline‐alkali marginal land, to remediate Cd‐contaminated acidic soil.
Shaoqing Ge, Zhenyong Zhao, Ke Zhang, Changyan Tian   +3 more
wiley   +1 more source

Integrative transcriptomic and metabolomic profiling elucidates the metabolic network underlying development in Salsola collina. [PDF]

BMC Plant Biol
Chen Y, Bi W, Hao J, Li S, Wu W, Zheng S, Wang M, Fan Y, Ma Y, Ya H.   +9 more
europepmc   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Integrated Transcriptome and Metabolome Analysis Reveals Differential Berberine Biosynthesis in Leaves and Stems of <i>Phellodendron amurense</i> Rupr. Plantlets. [PDF]

Curr Issues Mol Biol
Li W, Wang X, Lv C, Wang Y, Wang Y, Koski TM, Du K, Wang J.   +7 more
europepmc   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Integrated metabolomics and transcriptomics investigate the bulb-specific biosynthesis of medicinal steroidal alkaloids in Fritillaria taipaiensis. [PDF]

BMC Plant Biol
Guo J, Zhong X, Zhou L, Chen K, Wei M, Gao X, Wang S, Qian Z, Cui L, Qiang Y, Ren H.   +10 more
europepmc   +1 more source

Artificial Intelligence‐Driven Natural Product Drug Discovery: From Computational Genome Mining to Clinical Translation

Medicinal Research Reviews, EarlyView.
ABSTRACT Natural products (NPs) have historically yielded numerous therapeutic agents, yet their integration into modern drug discovery has been constrained by chemical complexity, low abundance, laborious dereplication, and limited target annotation.
Antonio Lavecchia
wiley   +1 more source

A review on Mitragyna alkaloids pharmacology, biosynthesis and biotechnological insights. [PDF]

J Genet Eng Biotechnol
Wangmo KS, Wungsintaweekul J, Zhu Z, Yang M, Jaisi A.   +4 more
europepmc   +1 more source

Decoding Molecular Mechanisms of Pongamia pinnata Phytochemicals in Cancer Therapy

Medicine Advances, EarlyView.
Pongamia pinnata phytochemicals have multiple anticancer mechanisms, including antioxidant, anti‐inflammatory, anti‐metastatic, and apoptosis‐inducing activities through molecular‐level regulation. These bioactive compounds protect normal cells from oxidative stress while promoting reactive oxygen species‐mediated tumor cell death and suppressing ...
Rajib Dhar, Vetriselvan Subramaniyan
wiley   +1 more source