Results 161 to 170 of about 232,220 (312)

Palladium-catalyzed amination of quinaldine-5-triflate

Open Chemistry, 2008
Fekete Melinda, Töröncsi Mercedesz, Novak Lajos   +2 more
doaj   +1 more source

Total Synthesis of the Spirocyclic Bis-Indole Alkaloid (-)-Owerreine via a [4+2] Annulation. [PDF]

Angew Chem Int Ed Engl
Coll E, Gandon V, Kouklovsky C, Evanno L, Vincent G.   +4 more
europepmc   +1 more source

Tropane alkaloids in food [PDF]

A large number of wild and cultured plants produce secondary metabolites that are toxic to humans and animals. Through accidental or intentional mixing of these plants with normal food and feed the consumers of these products will be exposed to the ...
Adamse, P., Egmond, H.P., van
core   +1 more source

Orthologue inference-based enzyme mining for diversification of the anti-cancer evodiamine scaffold. [PDF]

Commun Chem
Kwan BD, Kim T, Nguyen HH, Wang J, Xia Z, Franke J, Dang TT.   +6 more
europepmc   +1 more source

Systemic anti‐cancer therapy associated with the occurrence of peripheral neurotoxicity and, specifically, peripheral neuropathy

International Journal of Cancer, EarlyView.
What's New? While the effectiveness of systemic anticancer therapy is well documented, it commonly causes severe toxicity. This study of the 467 systemic anticancer therapy agents currently approved globally for clinical and/or research purposes found that peripheral neurotoxicity is associated with 45% of classical chemotherapies, 21% of targeted ...
Cassie Higgins, Lynn R. Gauthier, Blair H. Smith, Lesley Colvin   +3 more
wiley   +1 more source

Molecular mechanisms of ABA-mediated cold stress response in Dendrobium officinale. [PDF]

BMC Plant Biol
Wang J, Wang R, Liu Q, Zhang Y, Zhou M, Yang S, Yang T, Gu R, Ren D, Sun Q, Zou J, Meng X, Chen J, Huang Y.   +13 more
europepmc   +1 more source

Metabolic Signatures and Diagnostic Prediction Models for Coronary Artery Disease and Type 2 Diabetes Mellitus: Insights From an Exploratory Study

iNew Medicine, EarlyView.
Metabolomic & lipidomic analysis reveals metabolic overlap between CAD & T2DM, highlighting 7 key metabolites as potential biomarkers. A predictive model based on these achieves high accuracy, potentially advancing precision medicine & metabolic insights.
Zhihua Wang, Meiming Su, Ying Li, Yapei Li, Shuo Chen, Ting Peng, Hans Strijdom, Jiangang Wang, Jianping Weng, Suowen Xu   +9 more
wiley   +1 more source

Iterative enrichment cultivation and multiomic analysis reveal potential endophytic bacteria affecting the sinomenine synthesis in Sinomenium acutum. [PDF]

Microb Cell Fact
Yin S, Xiao Z, Yu Z, Zhou C, Jian J, Xiao Y, Yang H.   +6 more
europepmc   +1 more source

Traditional Chinese Medicine and Natural Products Targeting Right Ventricular Dysfunction in Pulmonary Arterial Hypertension: Toward Precision Cardiometabolic Therapy

iNew Medicine, EarlyView.
Natural products and traditional Chinese medicine target metabolic pathways underlying right ventricular dysfunction in pulmonary arterial hypertension. Integrating multi‐omics, artificial intelligence, and systems biology may enable precision cardiometabolic therapies to restore right ventricular metabolism and improve clinical outcomes.
Yihao Wu, Zhehui Tang, Hongwei Yao
wiley   +1 more source

Investigating Opioid Receptor Activity through Biocatalytic Halogenation and Oxidation of Mitragynine. [PDF]

ACS Chem Biol
Harris NR, Powell AJ, Snodgrass HM, Amin S, Newmister SA, Curtis BJ, Li D, Husaini ZA, Verhey-Henke L, Smith JL, Pereira F, Lewis JC, Traynor J, Sherman DH.   +13 more
europepmc   +1 more source