Results 81 to 90 of about 225,386 (346)
Chemistry – A European Journal, Volume 28, Issue 67, December 1, 2022., 2022 The chemical evolution of polyketide natural products leads to the unprecedented combination of biosynthetically related fragments in arrangements not found in Nature. The pseudo‐natural product grismonone was identified to be a potent inhibitor of Hedgehog signaling – a bioactivity that is not shared by its guiding fragments.
Michael Grigalunas +9 more
wiley +1 more source
Cyclopropanation of carbon-carbon double bonds in ring d of ergot alkaloids [PDF]
, 2013 Some ergot alkaloid derivatives containing a double bond in ring D have been reacted with diazomethane/palladium diacetate reagent to result in formation of a fused cyclopropane ring.
Dörnyei, Gábor +5 more
core +1 more source
Macedonian Journal of Chemistry and Chemical EngineeringMultivariate analysis models were developed to evaluate the results obtained from a compatibility study designed for ibuprofen with a large group of different types of excipients, as a possible approach for rapid screening of the incompatibility between
Elena Cvetkovska Bogatinovska +3 more
doaj +1 more source
GAME9 regulates the biosynthesis of steroidal alkaloids and upstream isoprenoids in the plant mevalonate pathway [PDF]
, 2016 Steroidal glycoalkaloids (SGAs) are cholesterol-derived molecules produced by solanaceous species. They contribute to pathogen defence but are toxic to humans and considered as anti-nutritional compounds.
Aharoni, Asaph +13 more
core +1 more source
Herbal highs: review on psychoactive effects and neuropharmacology [PDF]
, 2017 Background: A new trend among users of new psychoactive substances’ the consumption of “herbal highs”: plant parts containing psychoactive substances.
Graziano, S +5 more
core +1 more source
Biosynthesis of the protoberberine alkaloid jatrorrhizine [PDF]
, 1983 Feeding experiments with distant single or doubly labelled precursors show that the methylene dioxy group of berberine is opened in the formation of ...
Beecher +8 more
core +1 more source
Jurnal Kimia Sains dan Aplikasi, 2013 Telah dilakukan proses isolasi senyawa alkaloid indol daun ketapang yang sudah menguning (Terminalia Cattapa Linn) dengan metode ekstraksi Asam-Basa. Hasil isolasi diperoleh senyawa alkaloid total sebesar 1,423 gram (percent 0,287%). Analisis menggunakan
Ferdian Cahya Prima +2 more
doaj +1 more source
Paravasation with cyclophosphamide - Case report of tissue necrosis in a patient with primary breast cancer [PDF]
, 2007 Background: Paravasation is a rare but severe complication of treatment with cytotoxic agents. Some anticancer drugs are considered to be of high toxicity (vesicant), some are merely irritant, and some are regarded as nearly non-toxic to healthy tissue ...
Adami NP +7 more
core +1 more source
Nukuhivensiums, Indolo[2,3-a]quinoliziniums from the Marquesan Plant Rauvolfia nukuhivensis
Molecules, 2012 The first phytochemical inspection of the Marquesan endemic plant Rauvolfia nukuhivensis led to the isolation and structure characterization of two new indolo[2,3‑a]quinolizinium derivatives named nukuhivensium (1) and N12-methyl-nukuhivensium (2).
Phila Raharivelomanana +4 more
doaj +1 more source
The Potential of Tetrandrine as a Protective Agent for Ischemic Stroke
Molecules, 2011 Stroke is one of the leading causes of mortality, with a high incidence of severe morbidity in survivors. The treatment to minimize tissue injury after stroke is still unsatisfactory and it is mandatory to develop effective treatment strategies for ...
Sheng-Hong Tseng, Ya-Hui Tsai, Yun Chen
doaj +1 more source