Expression and modulation of an NADPH oxidase in mammalian astrocytes [PDF]
, 2005 Amyloid β peptides generate oxidative stress in hippocampal astrocytes through a mechanism sensitive to inhibitors of the NADPH oxidase [diphenylene iodonium (DPI) and apocynin].
Abramov, A.Y. +5 more
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Physiological Reports, 2021 The high metabolic demand of cerebral tissue requires that local perfusion is tightly coupled with local metabolic rate (neurovascular coupling; NVC).
Taylor J. Bader +9 more
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Forebrain-independent generation of hyperthermic convulsions in infant rats [PDF]
, 2016 Febrile seizures are the most common type of convulsive events in children. It is generally assumed that the generalization of these seizures is a result of brainstem invasion by the initial limbic seizure activity.
Blumberg, Mark S. +4 more
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Case report: Severe respiratory failure caused by licorice
Frontiers in Pharmacology, 2023 Licorice, one of the most commonly used herbs, can cause hypokalemia, metabolic alkalosis, and apparent mineralocorticoid excess, also known as pseudoaldosteronism. Herein, we present a case of diaphragmatic dysfunction caused by licorice administration.
Hiroaki Taniguchi +7 more
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Acid-base abnormalities and liver dysfunction
Annals of Hepatology, 2022 In addition to the kidneys and lungs, the liver also plays an important role in the regulation of the Acid-Base Equilibrium (ABE). The involvement of the liver in the regulation of ABE is crucial because of its role in lactic acid metabolism, urea ...
Periklis Katopodis +2 more
doaj +1 more source
Population pharmacodynamic modeling and simulation of the respiratory effect of acetazolamide in decompensated COPD patients. [PDF]
PLoS ONE, 2014 Chronic obstructive pulmonary disease (COPD) patients may develop metabolic alkalosis during weaning from mechanical ventilation. Acetazolamide is one of the treatments used to reverse metabolic alkalosis.619 time-respiratory (minute ventilation, tidal ...
Nicholas Heming +7 more
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Fever, febrile seizures and epilepsy. [PDF]
, 2007 Seizures induced by fever (febrile seizures) are the most common type of pathological brain activity in infants and children. These febrile seizures and their potential contribution to the mechanisms of limbic (temporal lobe) epilepsy have been a topic ...
Baram, Tallie Z +4 more
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Time course of hemolysis in respiratory alkalosis [PDF]
Acta Medica Iranica, 1969 Blood pH and plasma hemoglobin concentration were measured in dog undergoing hyperventilation with or without 6 %CO 2. Blood pH rose in the first minutes in the alkalotic group and hemolysis appeared mostly during second hour after alkalosis was ...
A. Babaknia, M.A. Khoyi
doaj +2 more sources
Ameliorating Effect of Chloride on Nitrite Toxicity to Freshwater Invertebrates with Different Physiology: a Comparative Study Between Amphipods and Planarians [PDF]
, 2008 High nitrite concentrations in freshwater ecosystems may cause toxicity to aquatic animals. These living organisms can take nitrite up from water through their chloride cells, subsequently suffering oxidation of their respiratory pigments (hemoglobin ...
Alonso, A., Camargo, J.A.
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Mixed acid-base disorders, hydroelectrolyte imbalance and lactate production in hypercapnic respiratory failure: the role of noninvasive ventilation. [PDF]
PLoS ONE, 2012 BACKGROUND: Hypercapnic Chronic Obstructive Pulmonary Disease (COPD) exacerbation in patients with comorbidities and multidrug therapy is complicated by mixed acid-base, hydro-electrolyte and lactate disorders.
Claudio Terzano +6 more
doaj +1 more source