Results 191 to 200 of about 31,317 (246)

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

open access: yesAdvanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis   +7 more
wiley   +1 more source

Taxonomic distribution of alkane synthesizing aldehyde dehydrogenases across bacteria, fungi, plants, and animals. [PDF]

open access: yesBiotechnol Biofuels Bioprod
Ito M   +6 more
europepmc   +1 more source

TRIM47 Regulates Energy Metabolism via Glycolytic Reprogramming to Drive Hepatocellular Carcinoma Progression and Represents an Efficient Therapeutic Target

open access: yesAdvanced Science, EarlyView.
This study identifies TRIM47 as a key driver of liver cancer progression by promoting glycolysis through ubiquitin‐mediated degradation of the gluconeogenic enzyme FBP1. TRIM47 enhances glucose uptake, lactate and ATP production, and tumor growth and metastasis.
Weijie Sun   +17 more
wiley   +1 more source

Recent trends in microbial production of alkanes. [PDF]

open access: yesWorld J Microbiol Biotechnol
Hagaggi NSA, Abdul-Raouf UM.
europepmc   +1 more source

RIG‐I Mediated Neuron‐Specific IFN Type 1 Signaling in FUS‐ALS Induces Neurodegeneration and Offers New Biomarker‐Driven Individualized Treatment Options for (FUS‐)ALS

open access: yesAdvanced Science, EarlyView.
Using iPSC‐derived motoneurons and postmortem tissue from FUS‐ALS patients, it is demonstrated that increased mitochondrial transcription leads to elevated cytosolic double‐stranded RNA (dsRNA) levels. This aberrant accumulation activates a RIG‐I–dependent innate immune response leading to neurodegeneration, which is amenable for FDA‐ and EMA‐approved ...
Marcel Naumann   +26 more
wiley   +1 more source

Ants' semiochemicals deters Philaenus spumarius (Hemiptera: Aphrophoridae) activity on olive trees. [PDF]

open access: yesJ Econ Entomol
Smargiassi S   +10 more
europepmc   +1 more source

Room-Temperature Electrocatalytic Dehydrogenation and Partial Fragmentation of <i>n</i>-Alkanes. [PDF]

open access: yesJ Am Chem Soc
Zhang G   +7 more
europepmc   +1 more source

Harnessing Cooperative Energy Transfer and Hydrogen Atom Transfer for Direct Nitrogenations of Non-Activated Alkanes. [PDF]

open access: yesAngew Chem Int Ed Engl
Kolla ST   +4 more
europepmc   +1 more source

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