Results 131 to 140 of about 6,174 (170)

Landscape of extracellular small RNA and identification of biomarkers in multiple human cancers. [PDF]

iScience
Zhan S, Xu Y, Li B, Ge P, Zhang C, Zhou S, Yang T, Liang G, Ji L, Kong X, Yang P, Chen X, Zhang CY, Shen H, Luo X, Zhou Z, Wang Y.   +16 more
europepmc   +1 more source

Engineering Membrane-Bound Alkane Monooxygenase from Marinobacter sp. for Increased Activity in the Selective ω-Hydroxylation of Linear and Branched Aliphatic Esters

Spasic J, Nigl A, Cheon H, Kaiserer CL, Galušić S, van der Pol E, Malihan-Yap L, Park J, Kourist R.   +8 more
europepmc   +1 more source

The 6-methyladenine erasers ALKBH5 and FTO influence chemotherapy efficiency in bladder cancer cell lines. [PDF]

Ann Transl Med
Drigeard Desgarnier MC, Monshaugen I, Ougland R, Klungland A.   +3 more
europepmc   +1 more source

RNA modifications: molecular orchestrators of wound healing. [PDF]

Burns Trauma
Guo X, Liu L, Yang J, Dai Y, Zhang Q, Gu R, Tan M, Tang M, Nie X.   +8 more
europepmc   +1 more source

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DNA repair by bacterial AlkB proteins

Research in Microbiology, 2003
The Escherichia coli AlkB protein is an iron- and 2-oxoglutarate-dependent oxygenase, repairing 1-methyladenine and 3-methylcytosine lesions in DNA. AlkB homologues are present in a number of bacterial species, and some bacteria have two different AlkB proteins.
Pal Falnes, Torbjørn Rognes
exaly   +3 more sources

Structure and Function of Alkane Monooxygenase (AlkB)

Accounts of Chemical Research, 2023
Every year, perhaps as much as 800 million tons of hydrocarbons enters the environment; alkanes make up a large percentage of it. Most are transformed by organisms that utilize these molecules as sources of energy and carbon. Both aerobic and anaerobic alkane transformation chemistries exist, capitalizing on the presence of alkanes in both oxic and ...
John T. Groves, Liang Feng, Rachel Narehood Austin   +2 more
openaire   +2 more sources

AlkB demethylases flip out in different ways

DNA Repair, 2008
Aberrant methylations in DNA are repaired by base excision repair (BER) and direct repair by a methyltransferase or by an oxidative demethylase of the AlkB type. Yang et al. [Nature 452 (2008) 961-966] have now solved the crystal structure of AlkB and human AlkB homolog 2 (hABH2) in complex with DNA using an ingenious crosslinking strategy to stabilize
Geir Slupphaug, Cathrine Broberg Vågbø, Hans E Krokan   +2 more
exaly   +3 more sources

alkB homologs in thermophilic bacteria of the genus Geobacillus

Molecular Biology, 2008
Screening of alkane hydroxylase genes (alkB) was performed in the thermophilic aerobic bacteria of the genus Geobacillus. Total DNA was extracted from the biomass of 11 strains grown on the mixture of saturated C10-C20 hydrocarbons, PCR amplification of fragments of alkB genes was performed with degenerate oligonucleotide primers, PCR products were ...
Tamara Nazina, Tourova T P, Poltaraus A B   +2 more
exaly   +3 more sources

Alkane biodegradation in Pseudomonas aeruginosa strains isolated from a polluted zone: identification of alkB and alkB-related genes

Research in Microbiology, 2002
Pseudomonas aeruginosa strains that grow on crude oil as the sole source of carbon and energy were isolated from an environment in Morocco polluted by petroleum refinery effluents. The twenty isolates grew on saturated alkanes from C12 to C22. Three of the isolates were also able to grow on low molecular weight C6 to C10 n-alkanes, but the other 17 ...
Abdelhaq, Belhaj, Nicole, Desnoues, Claudine, Elmerich   +2 more
openaire   +4 more sources

Aberrant activity of the DNA repair enzyme AlkB

Journal of Inorganic Biochemistry, 2004
Escherichia coli AlkB is a DNA/RNA repair enzyme containing a mononuclear Fe(II) site that couples the oxidative decomposition of alpha-ketoglutarate (alphaKG) to the hydroxylation of 1-methyladenine or 3-methylcytosine lesions in DNA or RNA, resulting in release of formaldehyde and restoration of the normal bases.
Timothy F, Henshaw, Michael, Feig, Robert P, Hausinger   +2 more
openaire   +2 more sources