Results 71 to 80 of about 10,817 (260)

The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions

eLife, 2021
Three-methyl cytosine (3meC) are toxic DNA lesions, blocking base pairing. Bacteria and humans express members of the AlkB enzymes family, which directly remove 3meC. However, other organisms, including budding yeast, lack this class of enzymes.
Braulio Bonilla, Alexander J Brown, Sarah R Hengel, Kyle S Rapchak, Debra Mitchell, Catherine A Pressimone, Adeola A Fagunloye, Thong T Luong, Reagan A Russell, Rudri K Vyas, Tony M Mertz, Hani S Zaher, Nima Mosammaparast, Ewa P Malc, Piotr A Mieczkowski, Steven A Roberts, Kara A Bernstein   +16 more
doaj   +1 more source

Chemical biology of mutagenesis and DNA repair: cellular responses to DNA alkylation [PDF]

, 2009
The reaction of DNA-damaging agents with the genome results in a plethora of lesions, commonly referred to as adducts. Adducts may cause DNA to mutate, they may represent the chemical precursors of lethal events and they can disrupt expression of genes ...
Essigmann, John M., Li, Deyu, Shrivastav, Nidhi   +2 more
core   +3 more sources

The elite eating quality alleles Wxb and ALKb are regulated by OsDOF18 and coordinately improve head rice yield

Plant Biotechnology Journal
Summary Head rice yield (HRY) measures rice milling quality and determines final grain yield and commercial value. Here, we report that two major quantitative trait loci for milling quality in rice, qMq‐1 and qMq‐2, represent allelic variants of Waxy lv /
Maodi Zhu, Yongqiang Liu, G. Jiao, Junming Yu, Rumeng Zhao, Ao Lu, Wei Zhou, Ni Cao, Jiamin Wu, Shikai Hu, Z. Sheng, Xiangjin Wei, Fengli Zhao, Li-hong Xie, Shakeel Ahmad, Yongjun Lin, G. Shao, S. Tang, P. Hu   +18 more
semanticscholar   +1 more source

Plant n-alkane production from litterfall altered the diversity and community structure of alkane degrading bacteria in litter layer in lowland subtropical rainforest in Taiwan [PDF]

Biogeosciences, 2018
n-Alkane and alkane-degrading bacteria have long been used as crucial biological indicators of paleoecology, petroleum pollution, and oil and gas prospecting.
T.-Y. Huang, T.-Y. Huang, B.-M. Hsu, B.-M. Hsu, W.-C. Chao, C.-W. Fan   +5 more
doaj   +1 more source

Substrate binding and channeling allosterically modulate the interactions within the AlkB-AlkG electron transfer complex

bioRxiv
Karolina Mikulska‐Ruminska, Matthew Licht, Mehmed Z. Ertem, John Shanklin, John Shanklin, İvet Bahar   +5 more
openalex   +2 more sources

Suppression of Escherichia coli alkB mutants by Saccharomyces cerevisiae genes [PDF]

Journal of Bacteriology, 1995
The alkB gene is one of a group of alkylation-inducible genes in Escherichia coli, and its product protects cells from SN2-type alkylating agents such as methyl methanesulfonate (MMS). However, the precise biochemical function of the AlkB protein remains unknown.
Ying-Fei Wei, Leona D. Samson, Beiru Jia Chen   +2 more
openaire   +3 more sources

Marine crude-oil biodegradation: a central role for interspecies interactions [PDF]

, 2012
The marine environment is highly susceptible to pollution by petroleum, and so it is important to understand how microorganisms degrade hydrocarbons, and thereby mitigate ecosystem damage. Our understanding about the ecology, physiology, biochemistry and
Folwell, Benjamin D, McGenity, Terry J, McKew, Boyd A, Sanni, Gbemisola O   +3 more
core   +1 more source

Unique starch biosynthesis pathways in wild rice revealed by multi-omics analyses. [PDF]

Plant Biotechnol J
Summary Australian wild rice species (AWS) possess unique starch properties characterized by a slow digestibility rate. However, the genomic and transcriptomic variations of starch‐synthesis‐related genes (SSRGs) influencing starch physiochemical properties in AWS remain unclear.
Nurmansyah, Furtado A, Okemo P, Henry RJ.   +3 more
europepmc   +2 more sources

Recognition and processing of a new repertoire of DNA substrates by human 3-methyladenine DNA glycosylase (AAG) [PDF]

, 2009
The human 3-methyladenine DNA glycosylase (AAG) recognizes and excises a broad range of purines damaged by alkylation and oxidative damage, including 3-methyladenine, 7-methylguanine, hypoxanthine (Hx), and 1,N[superscript 6]-ethenoadenine (εA).
Aas P. A., Abner C. W., Adhikari S., Berti P. J., Bjelland S., Chakravarti D., Delaney J. C., Delaney J. C., Dianov G., Dosanjh M. K., Eftedal I., el Ghissassi F., Elder R. H., Engelward B. P., Falnes P. O., Falnes P. O., Falnes P. O., Frick L. E., Friedberg E. C., Gallagher P. E., Goodenough A. K., Guengerich F. P., Guengerich F. P., Guengerich F. P., Guliaev A. B., Hang B., Haushalter K. A., Hitchcock T. M., Koivisto P., Kusmierek J. T., Kusmierek J. T., Lau A. Y., Lau A. Y., Leonard N. J., Ludlum D. B., Miao F., Mishina Y., Nilsen H., Ougland R., O’Brien P. J., O’Brien P. J., O’Connor T. R., O’Connor T. R., O’Neill R. J., Pearl L. H., Pendlebury A., Ringvoll J., Roy R., Samson L., Saparbaev M., Saparbaev M., Saparbaev M., Singer B., Trewick S. C., Wang H., Westbye M. P., Wuenschell G. E., Wyatt M. D.   +57 more
core   +1 more source

Bioprospecting for Genes Encoding Hydrocarbon-Degrading Enzymes from Metagenomic Samples Isolated from Northern Adriatic Sea Sediments [PDF]

, 2018
Three metagenomic libraries were constructed using surface sediment samples from the northern Adriatic Sea. Two of the samples were taken from a highly polluted and an unpolluted site respectively.
Baranasic, Damir, Blažina, Maria, Cullum, John, Diminic, Janko, Gacesa, Ranko, Hranueli, Daslav, Kolesarić, Domagoj, Korlević, Marino, Long, Paul F., Najdek-Dragić, Mirjana, Orlić, Sandi, Oršolić, Davor, Starcevic, Antonio, Zucko, Jurica   +13 more
core   +3 more sources