Results 271 to 280 of about 86,457 (338)

Alcohols as alkylating agents in heteroarene C-H functionalization. [PDF]

Nature, 2015
Jin J, Jin J, MacMillan DW.
europepmc   +1 more source

Bismuth Bicycles

Journal of Peptide Science, Volume 32, Issue 3, March 2026.
Discovery, evolution and potential future applications of bismuth bicycle molecules—a novel class of therapeutics with unique properties. ABSTRACT Bicyclic peptides are emerging as next generation therapeutics by combining the affinity and specificity of antibodies with the synthetic convenience of small molecules.
Saan Voss, Amin Sagar, Arnaud Tiberghien, Richard J. L. Hughes, Liuhong Chen, Inmaculada Rioja, Mark Frigerio, Michael J. Skynner, David R. Spring   +8 more
wiley   +1 more source

Decreased spermatogonial quantity in prepubertal boys with leukaemia treated with alkylating agents. [PDF]

Leukemia, 2017
Poganitsch-Korhonen M, Masliukaite I, Nurmio M, Lähteenmäki P, van Wely M, van Pelt AMM, Jahnukainen K, Stukenborg JB.   +7 more
europepmc   +1 more source

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Plasma Proteomic Profile of Chemotherapy‐Induced Severe Neutropenia: A Pilot Discovery Phase Study

The FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Immune system, hemostasis, and protein metabolism are the major biological mechanistic effects affected by chemotherapy‐induced myelotoxicity treatment, which may underline tissue damage and systemic responses seen in patients' follow‐up treatment. ABSTRACT Transient severe neutropenia and thrombocytopenia are frequent during treatment of hematological
Leticia Queiroz da Silva, Alexander Leonardo Silva‐Junior, Licia C. Silva‐Costa, Ivanio Teixeira Borba‐Junior, Bradley J. Smith, Edilson Tadeu Andrade, Bruno Kosa Lino Duarte, Marcos Paulo Colella, Thiago Martins Santos, Daniel Martins‐de‐Souza, Erich Vinicius De Paula   +10 more
wiley   +1 more source

Comparison of Mechanical Properties of Lignin/High‐Density Polyethylene (HDPE) Composites and Wood/HDPE Composites

Journal of Applied Polymer Science, Volume 143, Issue 5, February 5, 2026.
Manufacturing process and mechanical testing of lignin polymer composites. ABSTRACT Lignin is a plant‐derived, the second most abundant natural polymer, and a waste byproduct of the pulp industry. Incorporation of lignin into plastic composites using scalable approaches is commercially favored and low carbon‐cost.
Yelin Ni, Madhusudhan R. Pallaka, Jose Ramos, Ethan K. Nickerson, Jaelynne A. King, Satish Nune, Keerti S. Kappagantula, David Heldebrant   +7 more
wiley   +1 more source

Photoinduced, Chemoselective γ‐Alkylation of 2‐Silyloxyfurans With α‐Bromoketones: A Rapid Entry to Chiral ε‐Keto‐γ‐Butenolides

Chemistry – A European Journal, Volume 32, Issue 5, 2 February 2026.
A photoinduced, regio‐ and chemoselective γ‐alkylation of 2‐silyloxyfurans with a‐bromoketones was achieved by exploiting a photoredox catalytic process promoted by blue light. This approach provides practical and efficient access to chiral, ε‐ketobutenolides, in one step and high yields.
Debora Guazzetti, Luca Aimi, Enrico Marcantonio, Giovanni Maria Siciliano, Kelly Bugatti, Sara Dobani, Andrea Sartori, Lucia Battistini, Franca Zanardi, Claudio Curti   +9 more
wiley   +1 more source

MCV/Q, Medical College of Virginia Quarterly, Vol. 15 No. 3 [PDF]

, 1981

core   +1 more source

A Riboflavin‐Derived Flavinium Salt Mediates Chemoselective Methylation Reactions

Chemistry – A European Journal, Volume 32, Issue 5, 2 February 2026.
A two‐component methylation protocol was developed, where the active flavin mediator can be recycled in a single step. Crystallographic data and NMR spectroscopy support the mechanistic proposal, while chemoselective methylation was observed for a broad range of biologically relevant substrates. ABSTRACT Selective methylation is among the most relevant
Tim Langschwager, Ekrem Suylu, Julian Zuber, Golo Storch   +3 more
wiley   +1 more source

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

Advanced Theory and Simulations, Volume 9, Issue 2, February 2026.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer, Sridhar Priyankha, Gopal Hema, Anouar Zerouali, Hamza Haddag, Muneerah Mogren Al Mogren, Muthuramalingam Prakash, Majdi Hochlaf   +7 more
wiley   +1 more source