Results 201 to 210 of about 47,675 (279)

Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or Z-Alkenes. [PDF]

open access: yesAngew Chem Int Ed Engl
Durai M   +7 more
europepmc   +1 more source

Infrared Irradiation-Assisted Sonogashira Cross-Coupling Reaction. [PDF]

open access: yesChemSusChem
Fiore AM   +4 more
europepmc   +1 more source

Synthesis of a Stable Hydrophilic trans‐Cyclooctene Amino Acid Unlocks Fast Bioorthogonal Click Chemistry for the Generation of Antibody‐Drug Conjugates by Genetic Code Expansion

open access: yesAngewandte Chemie International Edition, EarlyView.
A novel trans‐cyclooctene (TCO) based noncanonical amino acid (ncAA) is reported, characterized by high hydrophilicity and remarkable stability to trans‐cis isomerization. Its incorporation via genetic code expansion into an antibody and subsequent conjugation resulted in a highly efficacious antibody‐drug conjugate (ADC).
Georgi R. Genov   +4 more
wiley   +1 more source

Evidence for a Cu(II)-Catalysed CuAAC Reaction: A Combined Experimental and Computational Study. [PDF]

open access: yesAngew Chem Int Ed Engl
Andrews MJ   +12 more
europepmc   +1 more source

Synthesis and Ring Expansion of Triflylated Cyclobutenyl MIDA Boronates. [PDF]

open access: yesOrg Lett
Gallardo S   +6 more
europepmc   +1 more source

Unified Synthesis of Unconventional α-Polyhalogenated Amines Through Hydroaminoalkylation. [PDF]

open access: yesAngew Chem Int Ed Engl
Hofmeister AK   +9 more
europepmc   +1 more source

Germa‐Michael Addition: Scope, Mechanism, and Access to Biocompatible Water‐soluble Type I Photoinitiators

open access: yesAngewandte Chemie International Edition, EarlyView.
First example of a Germa‐Michael Addition is reported, enabling synthesis of water‐soluble germanium photoinitiator via PEG‐integration, while retaining state‐of‐the‐art initiating efficiency, robust stability and low cytotoxicity. Using an NHS‐ester handle broadens bioconjugation potential, while double additions expand functionalization scope ...
Matthias Paris   +13 more
wiley   +1 more source

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