Synthesis of aryl-1H-1,2,3-triazoles via 1,3-dipolar cycloaddition
Orbital: The Electronic Journal of Chemistry, 2012 A series of Aryl-1H-1,2,3-triazoles were prepared from the reaction between aril-azide (1) with 1.5 equiv. of terminal alkynes (2a-o). The reactions carried out at room temperature and in the presence of CuI (10 mol%) in acetonitrile. The compounds (3a-o)
Wagner O. Valença +2 more
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Formation of Bicyclic Pyrroles from the Catalytic Coupling Reaction of 2,5-disubstituted Pyrroles with Terminal Alkynes, Involving the Activation of Multiple C-H bonds [PDF]
, 2008 Substituted bicyclic pyrroles are produced directly from the coupling reaction of 2,5-disubstituted pyrroles with terminal alkynes, involving the activation of multiple C–H bonds and regioselective ...
Yi, Chase S., Zhang, Jie
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Manganese carbonyl-mediated reactions of azabutadienes with phenylacetylene, methyl acrylate and other unsaturated molecules [PDF]
, 2004 Reaction of PhCH₂Mn(CO)₅ with l,4-di-aryl-1-aza-1,3-butadienes gave substituted pyrrolinonyl rings which were η⁴-coordinated to a Mn(CO)₃ group. These are formed by intramolecular CO insertion into a (non-isolated) cyclomanganated intermediate, followed ...
Mace, Wade +3 more
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Communications Chemistry, 2022 Intermolecular (4 + 2) cycloaddition with alkynes is a powerful approach to construct isocoumarin moieties, however, regioselectivity remains challenging for the transition metal-catalyzed approach.
Weilin Wang +5 more
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Reactions of Tetracyclone Molybdenum Complexes with Electrophilic Alkynes: Cyclopentadienone–Alkyne Coupling and Alkyne Coordination [PDF]
Organometallics, 2017 The reactions of the complexes [Mo(CO)2(η4-C4Ph4CO)2] and [Mo(CO)3(NCMe)(η4-C4Ph4CO)] with the alkynes dimethyl acetylenedicarboxylate (DMAD; RC≡CR where R = CO2Me) and methyl propiolate (RC≡CH) have been studied. In the case of DMAD, the initial product is the green carbonyl complex [Mo(CO)(RC≡CR)(η5,σ-C4Ph4COCR═CR)] (3), in which two alkyne molecules
Adams, H. +4 more
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Coordinatively unsaturated ruthenium complexes as efficient alkyne-azide cycloaddition catalysts [PDF]
, 2012 The performance of 16-electron ruthenium complexes with the general formula Cp*Ru(L)X (in which L = phosphine or N-heterocyclic carbene ligand; X = Cl or OCH2CF3) was explored in azide−alkyne cycloaddition reactions that afford the 1,2,3- triazole ...
Broggi, Julie +6 more
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DFT-Assisted Design and Evaluation of Bifunctional Amine/Pyridine-Oxazoline Metal Catalysts for Additions of Ketones to Unactivated Alkenes and Alkynes [PDF]
, 2018 Bifunctional catalyst systems for the direct addition of ketones to unactivated alkenes/alkynes were designed and modeled by density functional theory (DFT).
Dockendorff, Chris +2 more
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Beilstein Journal of Organic Chemistry, 2019 An iodine-mediated hydration reaction of alkynes serves as a green alternative to metal-catalyzed procedures. Previous work has shown that this method works well with terminal alkynes on keto-functionalized scaffolds, including 1,3-dicarbonyls and their ...
Zachary Lee +8 more
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Efficient Sonogashira Coupling Reaction Catalyzed by Copper (I) Iodide in the Presence of KF/Al2O3 [PDF]
شیمی کاربردی روز, 2009 We have developed a convenient and efficient method for coupling of aryl iodides and bromides with terminal alkynes. The protocol uses CuI as catalyst, 1, 10-phenanthroline as ligand, KF/Al2O3 as base and toluene as solvent.
Rahman Hosseinzadeh +2 more
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One-pot multi-reaction processes: synthesis of natural products and drug-like scaffolds [PDF]
, 2014 One-pot multi-reaction processes involving Overman rearrangements, metathesis cyclizations, and Diels–Alder reactions have been developed for the rapid and efficient synthesis of amino-substituted carbocyclic and heterocyclic compounds.
Calder, Ewen D.D. +2 more
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