Results 121 to 130 of about 21,779,284 (300)

Osteoporosis risk and its association with all-cause and cause-specific mortality among the elderly: a 16-year nationwide cohort study

open access: yesBMC Geriatrics
Background Aged osteoporosis poses a significant threat to the well-being and longevity of older individuals, yet evidence regarding the relationship between osteoporosis risk and mortality among the elderly population in Asia remains unknown.
Xing-Bing Pan   +6 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Health Inequality Profiles 2008 - All age, all cause standardised vs. EoE

open access: yes, 2009
DSRs (with CIs) for All age, all cause mortality 2001-03 to 2005-07, by gender, for Counties/UAs, County quintiles, County 80/20 standardises - as in previous years - against East of England Census 2001 ...
D., Hain
core   +1 more source

Prevalence and Mortality Risk of Persistent Smoking After Myocardial Infarction in a Very-High-Risk Region of Southeastern Europe

open access: yesMedicina
Background and Objectives: Long-term real-world data regarding smoking cessation after myocardial infarction (MI) remain scarce in Southeastern Europe.
Aleksandra Milovančev   +6 more
doaj   +1 more source

Excess all-cause mortality in Norway in 2024

open access: yesScandinavian Journal of Public Health
Aims: The Norwegian Institute of Public Health calculated excess mortality for Norway in 2024 using a reference period that included 2023—a year with significant excess mortality—and concluded there was no excess mortality in 2024.
Richard Aubrey White   +3 more
openaire   +2 more sources

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Administration of dexmedetomidine in critically ill adult patients with hemorrhagic stroke: a retrospective cohort study of the MIMIC-IV database

open access: yesAnesthesiology and Perioperative Science
Objective Intensive care units (ICUs) widely utilize dexmedetomidine (DEX), which is a sedative agent, for its ability to maintain hemodynamic stability and provide neuroprotection.
Yuyao Zhu   +4 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Association Between ECG Abnormalities and Mortality in a Low‐Risk Population

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background The ECG is a simple, noninvasive screening method for cardiovascular disease and arrhythmia. The impact of ECG abnormality on mortality is not certain in low‐risk populations.
Sung Ho Lee   +8 more
doaj   +1 more source

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