Results 91 to 100 of about 22,179,291 (307)

The Impact of Tenapanor on Body Composition and Blood Pressure in Peritoneal Dialysis Patients: A Pilot Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Instruction Tenapanor potentially affects fluid volume and blood pressure. This study explored its effects on these parameters in patients undergoing peritoneal dialysis (PD). Methods We conducted a single‐arm, prospective observational study that enrolled 10 patients on PD with hyperphosphatemia who were newly initiated on tenapanor.
Shun Yoshida, Kengo Asahina, Keiichi Osano, Natsumi Saegusa, Kohei Yamamura, Kie Ohkoshi, Miho Shikata, Toshihisa Ishii, Makiko Konishi, Kazuya Takahashi, Kohei Uchimura, Ayumu Nakashima   +11 more
wiley   +1 more source

Educational differences in all-cause mortality by marital status [PDF]

Using life table measures, we compare educational differentials in all-cause mortality at ages 40 to 70 in Bulgaria to those in Finland and the United States. Specifically, we assess whether the relationship between education and mortality is modified by
Pekka Martikainen, Irma Elo, Iliana V. Kohler, Kirsten P. Smith   +3 more
core  

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Snapshot evaluation of acute and chronic heart failure in real-life in Turkey: A follow-up data for mortality

Anatolian Journal of Cardiology, 2020
Objective: Heart failure (HF) is a progressive clinical syndrome. SELFIE-TR is a registry illustrating the overall HF patient profile of Turkey. Herein, all-cause mortality (ACM) data during follow-up were provided. Methods: This is a prospective outcome
Mehmet Birhan Yılmaz, Emrah Aksakal, Uğur Aksu, Hakan Altay, Yıldırım Nesligül, Ahmet Çelik, Mehmet Ata Akil, Lütfü Bekar, Mustafa Gökhan Vural, Rengin Çetin Güvenç, Savaş Özer, Dilek Ural, Yüksel Çavuşoğlu, Lale Tokgözoğlu   +13 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Association between the number of teeth and all-cause mortality rate in the MASHAD Cohort Study [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects
Background. Previous studies have reported inconsistent results on the relationship between the number of teeth and all-cause mortality. There are several confounding factors in this relationship, especially age.
Sara Saffar Soflaei, Reza Ekrad-Ferezghi, Behnood Najjari, Mohammad Mobasheri, Seyed Mohammad Reza Mousavi, Arash Pourdad, Mohsen Moohebati, Gordon A. Ferns, Javad Sarabadani, Habibollah Esmaily, Majid Ghayour Mobarhan   +10 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

All-cause mortality associated with fungal secondary infections among COVID-19 patients who used AFT.

, 2022
(A): All-cause mortality associated with AFT and without AFT in fungal secondary infections among COVID-19 patients; (B): All-cause mortality associated with mono- and combination AFT in fungal secondary infections among COVID-19 patients; (C): All-cause
Malavalli Siddalingegowda Srikanth (13170357), Subramanian Ramaswamy (1856344), Madhan Ramesh (13170354), Teggina Math Pramod Kumar (13170360), Niharika Pathakamuri (13170351), Sujit Kumar Sah (13170345), Atiqulla Shariff (13170348), Krishna Undela (129851)   +7 more
core   +1 more source

Hemoglobin glycation index and mortality risk in metabolic dysfunction-associated steatotic liver disease patients: a novel U-shaped association

Scientific Reports
Identifying dependable prognostic indicators is essential for the efficient management of metabolic dysfunction-associated steatotic liver disease (MASLD).
Mengjie Zhao, Ning Sun, Yurong Cheng, Wantong Zhang, Jinjin Ji, Qiuyan Li, Fang Lu, Weiliang Weng   +7 more
doaj   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source