Results 71 to 80 of about 19,218,388 (302)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

All-cause and cardiovascular mortality among ethnic German immigrants from the Former Soviet Union: a cohort study [PDF]

, 2006
Ronellenfitsch U, Kyobutungi C, Becher H, Razum O. All-cause and cardiovascular mortality among ethnic German immigrants from the Former Soviet Union: a cohort study. BMC Public Health.
Kyobutungi, Catherine, Catherine Kyobutungi, Ronellenfitsch Ulrich, Ronellenfitsch, Ulrich, Kyobutungi Catherine, Heiko Becher, Razum, Oliver, Becher, Heiko, Razum Oliver, Ulrich Ronellenfitsch, Oliver Razum, Becher Heiko   +11 more
core   +2 more sources

Alcohol consumption and mortality from all causes, coronary heart disease, and stroke: results from a prospective cohort study of Scottish men with 21 years of follow up [PDF]

, 1999
Objectives: To relate alcohol consumption to mortality. Design: Prospective cohort study. Setting: 27 workplaces in the west of Scotland. Participants: 5766 men aged 35-64 when screened in 1970-3 who answered questions on their usual weekly alcohol
Hole, D.J., Davey Smith, G., Hart, C.L., Hawthorne, V.M.   +3 more
core   +5 more sources

Endothelial Activation and Stress Index Predicts All‐Cause and Cardiovascular Mortality in Hypertensive Individuals: A Nationwide Study

The Journal of Clinical Hypertension
Emerging evidence links the Endothelial Activation and Stress Index (EASIX) and mortality risk in coronary artery disease, but its relevance in hypertensive patients remains unclear.
Gaiying Dong, Tingting Wu, Xiaofan Gu, Liangliang Wu   +3 more
doaj   +1 more source

All-cause mortality supports the COVID-19 mortality in Belgium and comparison with major fatal events of the last century

Archives of Public Health, 2020
Background The COVID-19 mortality rate in Belgium has been ranked among the highest in the world. To assess the appropriateness of the country’s COVID-19 mortality surveillance, that includes long-term care facilities deaths and deaths in possible cases,
Natalia Bustos Sierra, Nathalie Bossuyt, Toon Braeye, Mathias Leroy, Isabelle Moyersoen, Ilse Peeters, Aline Scohy, Johan Van der Heyden, Herman Van Oyen, Françoise Renard   +9 more
doaj   +1 more source

Diabetes modifies the association of prehypertension with cardiovascular disease and all‐cause mortality

The Journal of Clinical Hypertension, 2021
Prehypertension is a risk factor for cardiovascular disease (CVD) and all‐cause mortality. However, it is unclear whether prehypertension combined with diabetes associate with a higher risk for cardiovascular disease and all‐cause mortality.
Yanlong Ren, Yingting Zuo, Anxin Wang, Shuohua Chen, Xue Tian, Haibin Li, Yan He, Shouling Wu, Changsheng Ma   +8 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Educational differences in all-cause mortality by marital status [PDF]

Using life table measures, we compare educational differentials in all-cause mortality at ages 40 to 70 in Bulgaria to those in Finland and the United States. Specifically, we assess whether the relationship between education and mortality is modified by
Pekka Martikainen, Irma Elo, Iliana V. Kohler, Kirsten P. Smith   +3 more
core