Results 51 to 60 of about 16,019,830 (296)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

Synthesis of arbitrary current mode filter

Tongxin xuebao, 2010
A new general analytical synthesis method for arbitrary current mode filter was presented.The method was based on the analytical decomposition of a complicated high-order transfer function into n lossless integrators and n cur-rent proportional blocks by
LI Zhi-jun1, WANG Chun-hua2, LIU Rong1
doaj   +2 more sources

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

All-Pass Filter IC Design and Its Cascaded Second-Order and Third-Order All-Pass Filters and Quadrature Sinusoidal Oscillator Applications

IEEE Access
This study presents the design and application of a cascaded voltage-mode (VM) first-order all-pass filter (APF) integrated circuit (IC) based on a positive differential current conveyor (DDCC+).
Hua-Pin Chen, San-Fu Wang, Yitsen Ku, Liang-Yen Chen, Tzu-Yi Liu   +4 more
doaj   +1 more source

Three-Input Single-Output Voltage-Mode Multifunction Filter with Electronic Controllability Based on Single Commercially Available IC

Active and Passive Electronic Components, 2017
This paper presents a second-order voltage-mode filter with three inputs and single-output voltage using single commercially available IC, one resistor, and two capacitors.
Supachai Klungtong, Dusit Thanapatay, Winai Jaikla   +2 more
doaj   +1 more source

A Transconductance-Mode Multifunction Filter with High Input and High Output Impedance Nodes Using Voltage Differencing Current Conveyors (VDCCs)

Advances in Electrical and Electronic Engineering, 2020
The design of transconductance-mode multifunction biquad filter containing three input voltage nodes and single-output current node is proposed. Its circuit principle is emphasized on employing Voltage Differencing Current Conveyor (VDCC) to be an active
Montree Siripruchyanun, Winai Jaikla
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Applying the Hirose-Kamada filter to Swiss data: Output gap and exchange rate pass-through estimates [PDF]

Multivariate filters based on the Hodrick-Prescott filter are appealing because they combine the advantages of the Hodrick-Prescott filter with economic relationships.
Enzo Rossi, Franziska Bignasca
core