Results 211 to 220 of about 1,408,208 (397)

In Vivo‐Like Scaffold‐Free 3D In Vitro Models of Muscular Dystrophies: The Case for Anchored Cell Sheet Engineering in Personalized Medicine

Advanced Healthcare Materials, EarlyView.
The scaffold‐free Anchored Cell Sheet Engineering platform is used to create three‐dimensional (3D) in vitro models of skeletal muscle tissue that replicate key features of Duchenne and Myotonic dystrophies. These personalized tissue models, validated by histological, immunostaining, and proteomics analyses, accurately mimic disease phenotypes and ...
Alireza Shahin‐Shamsabadi, John Cappuccitti   +1 more
wiley   +1 more source

Crossing-Over Between Alleles at the Lozenge Locus in Drosophila Melanogaster

, 1949
M. M. Green, K. C. Green
openalex   +1 more source

A NEW COLOR ALLELE AT THE e LOCUS OF DROSOPHILA POLYMORPHA FROM NORTHERN SOUTH AMERICA [PDF]

, 1963
William B. Heed, Patrick R Blake
openalex   +1 more source

Autologous Peripheral Vγ9Vδ2 T Cell Synergizes with αβ T Cell Through Antigen Presentation and BTN3A1 Blockade in Immunotherapy of Cervical Cancer

Advanced Science, EarlyView.
This study provides proof‐of‐concept evidence showing that through direct killing, antigen presentation, and competitively binding to BTN3A1, Vγ9Vδ2 T cells amplified from cervical cancer (CC) patients can synergize with αβ T cells to exert anti‐CC function both in vitro and in vivo.
Min Wu, Jian Liu, Liting Liu, Yifan Yang, Hong Liu, Long Yu, Haihong Zeng, Shuo Yuan, Ruiyi Xu, Hangyu Liu, Han Jiang, Shen Qu, Liming Wang, Ying Chen, Jingyu Wang, Yuwei Zhang, Shan He, Ling Feng, Junyan Han, Wanjiang Zeng, Hui Wang, Yafei Huang   +21 more
wiley   +1 more source

Performance of Liquid Biopsy‐Based Multi‐Omics Biomarkers for Early Detection of Gynecological Malignancies: A Prospective Study (PERCEIVE‐I)

Advanced Science, EarlyView.
Following a comparative analysis of omics‐based cancer detection models, a novel liquid biopsy‐based multi‐omics combined model is developed for the early detection of gynecological malignancies. By integrating cell‐free DNA methylation and tumor protein markers, the combined model demonstrates high specificity and sensitivity and is uniquely designed ...
Zheng Feng, Huijuan Ge, Jingshu Wang, Yanan Wang, Xiaoran Sun, Bo Yang, Siyu Cao, Chenlian Quan, Qinhao Guo, Yusheng Han, Feidie Duan, Fang liu, Jing Zhao, Guoqiang Wang, Yuzi Zhang, Shangli Cai, Xiaohua Wu, Hao Wen   +17 more
wiley   +1 more source

ROLE OF LINKAGE IN GENE FREQUENCY CHANGE OF COAT COLOR ALLELES IN MICE [PDF]

, 1968
Philip W. Hedrick, R. E. Comstock
openalex   +1 more source

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

Cell, 2017
N. Mcgranahan, R. Rosenthal, C. Hiley, Andrew Rowan, T. Watkins, G. Wilson, Nicolai J. Birkbak, S. Veeriah, P. Van Loo, Javier Herrero, C. Swanton, Charles Mariam Selvaraju Seema Justyna Diana Joanne Letici Swanton Jamal-Hanjani Veeriah Shafi Czyzewska-Khan, C. Swanton, M. Jamal-Hanjani, S. Veeriah, S. Shafi, J. Czyzewska-Khan, Diana H. Johnson, J. Laycock, Leticia Bosshard-Carter, R. Rosenthal, Pat Gorman, R. Hynds, G. Wilson, Nicolai J. Birkbak, T. Watkins, N. Mcgranahan, S. Horswell, R. Mitter, M. Escudero, A. Stewart, P. Van Loo, Andrew Rowan, Hang Xu, S. Turajlic, C. Hiley, C. Abbosh, J. Goldman, R. Stone, Tamara Denner, Nik Matthews, G. Elgar, S. Ward, Marta Costa, Sharmin Begum, B. Phillimore, T. Chambers, E. Nye, S. Graça, M. Al Bakir, K. Joshi, A. Furness, Assma Ben Aissa, Y. Wong, A. Georgiou, S. Quezada, J. Hartley, H. Lowe, Javier Herrero, David S. Lawrence, M. Hayward, N. Panagiotopoulos, S. Kolvekar, M. Falzon, E. Borg, T. Marafioti, C. Simeon, G. Hector, Amy Smith, M. Aranda, M. Novelli, D. Oukrif, S. Janes, R. Thakrar, Martin D. Forster, T. Ahmad, S. Lee, D. Papadatos-Pastos, D. Carnell, R. Mendes, J. George, N. Navani, Asia Ahmed, Magali N. Taylor, Junaid Choudhary, Y. Summers, R. Califano, Paul Taylor, R. Shah, P. Krysiak, K. Rammohan, E. Fontaine, R. Booton, M. Evison, P. Crosbie, Stuart Moss, F. Idries, L. Joseph, P. Bishop, Anshuman Chaturved, A. Quinn, H. Doran, Angela E. Leek, P. Harrison, K. Moore, Rachael Waddington, Juliette Novasio, F. Blackhall, J. Rogan, E. Smith, C. Dive, J. Tugwood, G. Brady, D. Rothwell, Francesca Chemi, J. Pierce, Sakshi Gulati, B. Naidu, G. Langman, S. Trotter, M. Bellamy, H. Bancroft, A. Kerr, S. Kadiri, J. Webb, G. Middleton, M. Djearaman, D. Fennell, J. Shaw, J. Le Quesne, D. Moore, A. Nakas, S. Rathinam, W. Monteiro, H. Marshall, Louise Nelson, J. Bennett, Joan Riley, L. Primrose, L. Martinson, G. Anand, Sajid Khan, A. Amadi, M. Nicolson, K. Kerr, Shirley Palmer, H. Remmen, Joy Miller, K. Buchan, M. Chetty, L. Gomersall, Jason Lester, Alison Edwards, Fiona Morgan, Haydn Adams, H. Davies, M. Kornaszewska, R. Attanoos, S. Lock, A. Verjee, M. Mackenzie, M. Wilcox, Harriet Bell, A. Hackshaw, Y. Ngai, Sean Smith, N. Gower, C. Ottensmeier, S. Chee, Benjamin Johnson, A. Alzetani, E. Shaw, Eric Lim, P. De Sousa, M. T. Barbosa, A. Bowman, S. Jordan, A. Rice, H. Raubenheimer, C. Proli, M. E. Cufari, J. Ronquillo, Angela Kwayie, H. Bhayani, Morag Hamilton, Yusura Bakar, N. Mensah, L. Ambrose, A. Devaraj, S. Buderi, J. Finch, L. Azcárate, Hema Chavan, Sophie Green, Hillaria Mashinga, A. Nicholson, K. Lau, M. Sheaff, Peter D. Schmid, J. Conibear, V. Ezhil, Babikir Ismail, Melanie Irvin-sellers, V. Prakash, P. Russell, T. Light, T. Horey, S. Danson, J. Bury, John Edwards, Jennifer Hill, S. Matthews, Yota Kitsanta, K. Suvarna, P. Fisher, Allah Dino Keerio, M. Shackcloth, J. Gosney, P. Postmus, Sarah L. Feeney, Julius Asante-Siaw, H. Aerts, S. Dentro, C. Dessimoz   +223 more
semanticscholar   +1 more source

Roles of Kdm6a and Kdm6b in Regulation of Mammalian Neural Regeneration

Advanced Science, EarlyView.
This study reveals that Kdm6a plays key roles in repressing either peripheral nervous system (PNS) or central nervous system (CNS) axon regeneration, whereas Kdm6b is not involved in regulating CNS axon regeneration. Moreover, both demethylases are able to regulate CNS neuronal survival after injury, but with non‐overlapping mechanisms.
Shu‐Guang Yang, Chang‐Ping Li, Xue‐Wei Wang, Tao Huang, Cheng Qian, Qiao Li, Ling‐Rui Zhao, Si‐Yu Zhou, Chen‐Yun Ding, Rui Nie, Saijilafu, Yu‐Cai Hong, Chang‐Mei Liu, Feng‐Quan Zhou   +13 more
wiley   +1 more source

UFMylation of NLRP3 Prevents Its Autophagic Degradation and Facilitates Inflammasome Activation

Advanced Science, EarlyView.
This article studies the role of UFMylation in NLRP3 inflammasome activation. It reveals that UFMylation, mediated by the E3 Ufm1‐ligase 1 (Ufl1), maintains NLRP3 stability by preventing its ubiquitination and subsequent autophagic degradation.
Jiongjie Jing, Fan Yang, Ke Wang, Mintian Cui, Ni Kong, Shixi Wang, Xiaoyue Qiao, Fanyu Kong, Dongyang Zhao, Jinlu Ji, Lunxian Tang, Jiaxin Gao, Yu‐Sheng Cong, Deqiang Ding, Kun Chen   +14 more
wiley   +1 more source

Cutaneous T‐cell lymphomas: 2023 update on diagnosis, risk‐stratification, and management

American Journal of Hematology, Volume 98, Issue 1, Page 193-209, January 2023., 2023
Abstract Disease Overview Cutaneous T‐cell lymphomas are a heterogenous group of T‐cell neoplasms involving the skin, the majority of which may be classified as Mycosis Fungoides (MF) or Sézary Syndrome (SS). Diagnosis The diagnosis of MF or SS requires the integration of clinical and histopathologic data.
Alexandra C. Hristov, Trilokraj Tejasvi, Ryan A. Wilcox   +2 more
wiley   +1 more source