Results 211 to 220 of about 1,182,497 (331)

MIR17 wt Allele [PDF]

, 2020
National Cancer Institute
openalex   +1 more source

A Robust Serum Proteomic Signature of the E2 Allele of Apolipoprotein E

Advanced Science, EarlyView.
This study expands a serum protein signature of the e2 allele of APOE using multiple proteomic platforms and UK Biobank replication. The signature supports the role of APOE in lipid regulation through apolipoproteins and inflammation and includes, among others, neutrophil secreted granule proteins CAMP, CTSG, DEFA3, and MPO that point to inhibition of ...
Paola Sebastiani, Eric Reed, Kevin B Chandler, Prisma Lopez, Hannah Lords, Harold Bae, Catherine E Costello, Matthew Au, Lingyi Lynn Deng, Mengze Li, Qingyan Xiang, Heeju Noh, Lance Pflieger, Cory Funk, Noa Rappaport, Marianne Nygaard, Meghan I Short, Michael Brent, Stefano Monti, Stacy L Andersen, Thomas T Perls   +20 more
wiley   +1 more source

Generation and characterization of a mouse model of conditional Chd4 knockout in the endometrial epithelium. [PDF]

PLoS One
Harkins SK, Skalski HJ, Bennett AZ, Pavliscak LA, Sany NC, Arendt AR, Wood L, Moldovan GE, Chandler RL.   +8 more
europepmc   +1 more source

Impaired CFTR function in mild cystic fibrosis associated with the S977F/T5TG12complex allele in trans with F508del mutation [PDF]

, 2013
Claudio Sorio, Chiara Angiari, Jan Johansson, Genny Verzè, Michele Ettorre, Mario Buffelli, Carlo Castellani, B.M. Assael, Paola Melotti   +8 more
openalex   +1 more source

NAD⁺ Reduction in Glutamatergic Neurons Induces Lipid Catabolism and Neuroinflammation in the Brain via SARM1

Advanced Science, EarlyView.
NAD⁺ homeostasis maintains neuronal integrity through opposing actions of NMNAT2 and SARM1. Loss of NMNAT2 in glutamatergic neurons reprograms cortical metabolism from glucose to lipid catabolism, depletes lipid stores, and triggers inflammation and neurodegeneration.
Zhen‐Xian Niou, Sen Yang, Andrea Enriquez, Nino A. Espinas, Anoosha Sri, Caliel D. Hines, Jason M. Tennessen, Chia‐Shan Wu, Jui‐Yen Huang, Hui‐Chen Lu   +9 more
wiley   +1 more source

Association of IL28B Polymorphisms With Hepatitis C Susceptibility in Southern Iran's β-Thalassemia Population: A Cross-Sectional Study. [PDF]

Health Sci Rep
Askari F, Kargar M, Deris Zayeri Z, Jalalifar MA, Keikhaei B, Kaydani GA.   +5 more
europepmc   +1 more source

T Cell Receptor-γ Allele-Specific Selection of Vγ1/Vδ4 Cells in the Intestinal Epithelium [PDF]

, 2002
Kalliopi Grigoriadou, Laurent Boucontet, Pablo Pereira   +2 more
openalex   +1 more source

Intrinsic MicroRNA‐10a Restricts Regulatory T Cell Suppressive Function and Intestinal Repair by Coordinating Transcriptional, Metabolic, and Epithelial Repair Pathways

Advanced Science, EarlyView.
This study identifies microRNA‐10a (miR‐10a) as a key brake on regulatory T cell (Treg) suppressive function and intestinal repair. By targeting Blimp‐1, Uqcrq, and amphiregulin, miR‐10a restrains transcriptional, metabolic, and epithelial programs essential for Treg activity.
Wenjing Yang, Tianming Yu, Hui Yang, Suxia Yao, Ruihua Ma, Elizabeth M Steinert, Karen M Ridge, Weiguo Cui, Navdeep S Chandel, Yingzi Cong   +9 more
wiley   +1 more source

rs9789446 genotype as susceptibility biomarkers for congenital hypothyroidism based on population and family validation. [PDF]

Front Genet
Zhong X, Jia Y, Liu W, Qiao M, Li M, Yu X, Liu S.   +6 more
europepmc   +1 more source

Analysis of FMR1 (CGG)n alleles and FRAXA microsatellite haplotypes in the population of Greenland: implications for the population of the New World from Asia [PDF]

, 1999
Lars Allan Larsen, Judith S.M. Armstrong, Karen Grønskov, Helle Hjalgrim, Karen Brøndum‐Nielsen, Lis Hasholt, Bent Nørgaard‐Pedersen, Jens Vuust   +7 more
openalex   +1 more source