Splitting trees with neutral mutations at birth [PDF]
arXiv, 2013 We consider a population model where individuals behave independently from each other and whose genealogy is described by a chronological tree called splitting tree. The individuals have i.i.d. (non-exponential) lifetime durations and give birth at constant rate to clonal or mutant children in an infinitely many alleles model with neutral mutations ...
arxiv
TEMPORAL VARIATION IN THE RELATIONSHIP BETWEEN SIZE, NUMBERS, AND AN ALLELE‐FREQUENCY IN A POPULATION OF MYTILUS EDULIS [PDF]
, 1977 Roger Milkman, Richard K. Koehn
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Mitochondrial DNA disorders in neuromuscular diseases in diverse populations
Annals of Clinical and Translational Neurology, EarlyView.Abstract Neuromuscular features are common in mitochondrial DNA (mtDNA) disorders. The genetic architecture of mtDNA disorders in diverse populations is poorly understood. We analysed mtDNA variants from whole‐exome sequencing data in neuromuscular patients from South Africa, Brazil, India, Turkey and Zambia. In 998 individuals, there were two definite
Fei Gao +34 more
wiley +1 more source
The frequency of allele CCR5Δ32 in a Serbian population [PDF]
Journal of Medical Biochemistry, 2013 Background: The mutant CCR5Δ32 allele confers resistance to HIV infection. Several hypotheses regarding its origin and persistence in the human population have been proposed.
Đorđević Valentina +5 more
doaj
VDBP Gene Polymorphism in COPD
Medicine Science, 2013 Chronic obstructive pulmonary disease (COPD) is a disease which genetic and environmental factors play an important role in COPD development. VDBP (Vitamin D Binding Protein ) gene might be responsible for COPD development.
Sadan Soyyigit +3 more
doaj +1 more source
When do factors promoting balanced selection also promote population persistence? A demographic perspective on Gillespie's SAS-CFF model [PDF]
arXiv, 2019 Classical stochastic demography predicts that environmental stochasticity reduces population growth rates and, thereby, can increase extinction risk. In contrast, the SAS-CFF model demonstrates that environmental stochasticity can promote genetic diversity.
arxiv
Maintenance of an aminopeptidase allele frequency cline by natural selection. [PDF]
, 1980 Richard K. Koehn +2 more
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Calcium modulating ligand confers risk for Parkinson's disease and impacts lysosomes
Annals of Clinical and Translational Neurology, EarlyView.Abstract Objective Several genetic loci known to confer risk for Parkinson's disease (PD) function in lysosomal pathways. We systematically screened common variants linked to PD risk by genome‐wide association studies (GWAS) for impact on cerebrospinal fluid (CSF) proteins reflecting lysosomal function.
Hanwen Zhang +16 more
wiley +1 more source
A unified model for wild resistance dynamics and weed control using herbicide [PDF]
arXiv, 2015 A major issue in the modelling of weed resistance to herbicide lies in effectively handling the wild dynamics, that is, the allele frequency prior to the herbicide application, and in particular when starting to use the herbicide. The wild allele frequency is a key variable as the resistance evolution is highly sensitive to it, moreover it is extremely
arxiv
Haemoglobin polymorphism in atlantic cod(Gadus morhua): Allele frequency variation between yearclasses in a Norwegian fjord stock [PDF]
, 1985 Jarle Mork, Gunnar Sundnes
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