Results 1 to 10 of about 14,201,582 (335)

Gene frequency distributions reject a neutral model of genome evolution. [PDF]

open access: yesGenome Biol Evol, 2013
Evolution of prokaryotes involves extensive loss and gain of genes, which lead to substantial differences in the gene repertoires even among closely related organisms.
Lobkovsky AE, Wolf YI, Koonin EV.
europepmc   +2 more sources

Gene frequency and distribution of human platelet antigen-1 to −6, −10, −15, and −21 of platelets donors in Wuhan, China [PDF]

open access: yesGlobal Medical Genetics
Background: In this study, the frequency of human platelet antigen (HPA) alleles and genotypes of platelet donors in Wuhan was evaluated and differences in HPA distribution between Wuhan and other regions in China were compared. Study Design and Methods:
Zhen Qu   +6 more
doaj   +2 more sources

Detecting and measuring selection from gene frequency data. [PDF]

open access: yesGenetics, 2014
Vitalis R   +3 more
europepmc   +2 more sources

Alpha-1 antitrypsin Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide: an update [PDF]

open access: yesInternational Journal of COPD, 2017
Ignacio Blanco,1 Patricia Bueno,2 Isidro Diego,3 Sergio Pérez-Holanda,4 Francisco Casas-Maldonado,5 Cristina Esquinas,6 Marc Miravitlles6,7 1Alpha1-Antitrypsin Deficiency Spanish Registry (REDAAT), Fundación Respira, Spanish Society of ...
Blanco I   +6 more
doaj   +2 more sources

Lifestyle Modifications on the Expression of TCF7L2 Gene Polymorphism: A Cross-sectional Study [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2022
Introduction: Type 2 Diabetes Mellitus (T2DM) is the result of the clustering of factors along with the communication between environmental factors and a strong hereditary component.
Geetha Bhaktha   +3 more
doaj   +1 more source

Establishment of platelet donor gene bank involving specific antigen HPA 1-6/10/15/21 by real-time fluorescent PCR

open access: yesZhongguo shuxue zazhi, 2023
Objective To research the genetic polymorphism of HPA 1-6/10/15/21 in platelet donors in Zhongshan area, and establish a gene bank of platelet donors with HPA locus.
Wensheng YUAN   +5 more
doaj   +1 more source

Investigation on the distribution frequency of Rh and Kell blood group antigens in the Uyghur population in Xinjiang and the molecular mechanism of Kell positive individuals

open access: yesZhongguo shuxue zazhi, 2022
Objective To investigate the distribution frequency and characteristics of Rh and Kell erythrocyte blood group antigens in Uygur population in Xinjiang, and to explore the molecular mechanism of K gene positive patients, so as to build a local rare blood
Jin QIU   +5 more
doaj   +1 more source

Distribution of ABO, Rh, Mn, P, h blood groups and gene frequency in Lahu ethnic minority in Yunnan

open access: yesZhongguo shuxue zazhi, 2022
Objective To understand the distribution and gene frequency of main red blood cell blood groups in Lahu ethnic minority and analyze the genetic characteristics of Lahu people.
Haixia HU   +8 more
doaj   +1 more source

Study on the gene frequency and polymorphism of 11 RBC blood group systems in RhD negtive population in Hunan, China

open access: yesZhongguo shuxue zazhi, 2022
Objective To investigate the gene frequency and polymorphism of RBC blood group systems in RhD negtive population in Hunan, so as to lay a foundation for clinical blood transfusion and construction of multiple rare blood group database.
Binbin ZOU   +4 more
doaj   +1 more source

Transcriptome Analysis of Targeted Mouse Mutations Reveals the Topography of Local Changes in Gene Expression. [PDF]

open access: yes, 2016
The unintended consequences of gene targeting in mouse models have not been thoroughly studied and a more systematic analysis is needed to understand the frequency and characteristics of off-target effects.
Adkisson, Michael   +9 more
core   +8 more sources

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