Results 21 to 30 of about 19,516,845 (337)
Frequency of RPE65 Gene Mutation in Patients with Hereditary Retinal Dystrophy
, 2022 OBJECTIVES: Hereditary retinal dystrophies are a rare group of diseases which are heterogeneous in genotype and phenotype and result in total blindness.
Munis Dündar +8 more
core +1 more source
Journal of Infection in Developing Countries, 2010 Introduction: Staphylococcus epidermidis strains are frequently associated with catheter-related infection, acute bacteremia, and hospital-acquired infection.
Mohammad Reza Pourmand +3 more
doaj +1 more source
ANALYSES OF GENE FREQUENCIES [PDF]
Genetics, 1973 ABSTRACT Models of variance components and their intraclass correlational equivalences are developed for genes falling into various categories of subdivisions within a population. Estimable functions are elaborated demonstrating that intraclass correlations can be estimated only relative to that for the least related genes in the ...
openaire +2 more sources
Nucleic Acids Res., 2019 The Allele Frequency Net Database (AFND, www.allelefrequencies.net) provides the scientific community with a freely available repository for the storage of frequency data (alleles, genes, haplotypes and genotypes) related to human leukocyte antigens (HLA)
F. González-Galarza +11 more
semanticscholar +1 more source
CHD1 Remodels Chromatin and Influences Transient DNA Methylation at the Clock Gene frequency
PLoS Genetics, 2011 Circadian-regulated gene expression is predominantly controlled by a transcriptional negative feedback loop, and it is evident that chromatin modifications and chromatin remodeling are integral to this process in eukaryotes. We previously determined that
W. Belden +4 more
semanticscholar +1 more source
Gamma frequency entrainment attenuates amyloid load and modifies microglia
Nature, 2016 Changes in gamma oscillations (20–50 Hz) have been observed in several neurological disorders. However, the relationship between gamma oscillations and cellular pathologies is unclear.
Hunter F. Iaccarino +15 more
semanticscholar +1 more source
Frequency and Pattern of Worldwide Ocular Gene Therapy Clinical Trials up to 2022
, 2023 The purpose of this study is to describe worldwide gene therapy clinical trials aimed at treating ophthalmic disorders. Information regarding all worldwide clinical trials was collected through 15 different sources, including ClinicalTrials.gov.
Hossein Ameri +2 more
core +1 more source
Update on Viral Gene Therapy Clinical Trials for Retinal Diseases [PDF]
, 2022 In 2001, the first large animal was successfully treated with a gene therapy that restored its vision. Lancelot, the Briard dog that was treated, suffered from a human childhood blindness called Leber's congenital amaurosis type 2.
Cheng, Shun-Yun, Punzo, Claudio
core +1 more source
Brazilian Journal of Otorhinolaryngology, 2010 Mutações no gene GJB2 constituem a principal causa de surdez genética de herança autossômica recessiva, sendo a mutação 35delG a mais comum em muitos grupos étnicos.
Melissa de Freitas Cordeiro-Silva +4 more
doaj +1 more source
Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants
Genome Biology, 2019 The sharp increase of plant genome and transcriptome data provide valuable resources to investigate evolutionary consequences of gene duplication in a range of taxa, and unravel common principles underlying duplicate gene retention.
X. Qiao +7 more
semanticscholar +1 more source