Results 21 to 30 of about 14,201,582 (335)

The HSV-1 Latency-Associated Transcript Functions to Repress Latent Phase Lytic Gene Expression and Suppress Virus Reactivation from Latently Infected Neurons [PDF]

, 2016
open access articleHerpes simplex virus 1 (HSV-1) establishes life-long latent infection within sensory neurons, during which viral lytic gene expression is silenced.
Coleman, Heather M., Connor, Viv, Efstathiou, Stacey, Hann, William, Harman, Laura E.R., Nicoll, Michael P., Proenca, Joao T., Shivkumar, Maitreyi   +7 more
core   +3 more sources

Variance of Gene Frequencies [PDF]

Evolution, 1969
Inbreeding, gene frequency variance, and their corresponding effective population numbers are now commonplace terms in population genetics. The concepts and much of the theory are classical (Wright, 1921, 1931; Fisher, 1930). More recent refinements and extensions of the theory by Crow and associates (Crow, 1954; Crow and Morton, 1955; Kimura and Crow,
openaire   +2 more sources

Allele frequency net database (AFND) 2020 update: gold-standard data classification, open access genotype data and new query tools

Nucleic Acids Res., 2019
The Allele Frequency Net Database (AFND, www.allelefrequencies.net) provides the scientific community with a freely available repository for the storage of frequency data (alleles, genes, haplotypes and genotypes) related to human leukocyte antigens (HLA)
F. González-Galarza, A. McCabe, E. J. M. Santos, James Jones, L. Takeshita, Nestor D. Ortega-Rivera, Glenda M Del Cid-Pavon, Kerry A Ramsbottom, G. Ghattaoraya, A. Alfirevic, D. Middleton, Andrew R. Jones   +11 more
semanticscholar   +1 more source

ANALYSES OF GENE FREQUENCIES [PDF]

Genetics, 1973
ABSTRACT Models of variance components and their intraclass correlational equivalences are developed for genes falling into various categories of subdivisions within a population. Estimable functions are elaborated demonstrating that intraclass correlations can be estimated only relative to that for the least related genes in the ...
openaire   +2 more sources

CHD1 Remodels Chromatin and Influences Transient DNA Methylation at the Clock Gene frequency

PLoS Genetics, 2011
Circadian-regulated gene expression is predominantly controlled by a transcriptional negative feedback loop, and it is evident that chromatin modifications and chromatin remodeling are integral to this process in eukaryotes. We previously determined that
W. Belden, Zachary A. Lewis, E. Selker, J. Loros, J. Dunlap   +4 more
semanticscholar   +1 more source

Prevalências das mutações 35delG/GJB2 e del (GJB6-D13S1830) em portadores de surdez não-sindrômica na população do Espírito Santo - Brasil Prevalence of 35delG/GJB2 and del (GJB6-D13S1830) mutations in patients with non-syndromic deafness from a population of Espírito Santo - Brazil

Brazilian Journal of Otorhinolaryngology, 2010
Mutações no gene GJB2 constituem a principal causa de surdez genética de herança autossômica recessiva, sendo a mutação 35delG a mais comum em muitos grupos étnicos.
Melissa de Freitas Cordeiro-Silva, Andressa Barbosa, Marília Santiago, Mariana Provetti, Eliete Rabbi-Bortolini   +4 more
doaj   +1 more source

Allelic frequency of beta-lactoglobulin gene in different cattle breeds

RUDN Journal of Agronomy and Animal Industries, 2023
The results of research on the frequency of genotypes AA, AB, BB and alleles A and B of milk protein beta-lactoglobulin in various cattle breeds over the past decades were presented and summarized.
Natalya A. Khudyakova, Irina S. Kozhevnikova, Alexandra O. Stupina, Inga A. Klassen, Iya V. Selkova   +4 more
doaj   +1 more source

The dynamics of gene expression changes in a mouse model of oral tumorigenesis may help refine prevention and treatment strategies in patients with oral cancer. [PDF]

, 2016
A better understanding of the dynamics of molecular changes occurring during the early stages of oral tumorigenesis may help refine prevention and treatment strategies.
Bertolus, Chloé, Caulin, Carlos, Chabaud, Sylvie, Foy, Jean-Philippe, Goudot, Patrick, Hong, Waun Ki, Lachuer, Joël, Lang, Wenhua, Lavergne, Emilie, Le Texier, Vincent, Lippman, Scott M, Perol, David, Saintigny, Pierre, Thomas, Emilie, Tortereau, Antonin   +14 more
core   +1 more source

Reporte de cuatro casos de pacientes con síndrome de Jarcho-Levin en el departamento de Antioquia, Colombia

Biomédica: revista del Instituto Nacional de Salud, 2009
El síndrome de Jarcho-Levin es una displasia esquelética con alteraciones en la morfogénesis vertebral y en la segmentación costal, que se manifiesta con hemivertebras, fusión vertebral o agenesia vertebral, y fusión costal.
Jorge Hernán Montoya, Olga Lucía Morales   +1 more
doaj   +1 more source

Human gene copy number spectra analysis in congenital heart malformations [PDF]

, 2012
The clinical significance of copy number variants (CNVs) in congenital heart disease (CHD) continues to be a challenge. Although CNVs including genes can confer disease risk, relationships between gene dosage and phenotype are still being defined.
Bick, David P., Broeckel, Ulrich, Goetsch, Mary A., Harris, Susan, Hidestrand, Mats, Mahnke, Donna K., Mitchell, Michael, Pelech, Andrew N., Simpson, Pippa, Stamm, Karl D., Struble, Craig, Tomita-Mitchell, Aoy, Tuffnell, Maureen E., Tweddell, James S.   +13 more
core   +2 more sources