Results 231 to 240 of about 5,538,585 (265)

Allele Frequency Net Database

Methods in molecular biology, 2018
The allele frequency net database (AFND, http://www.allelefrequencies.net ) is an online web-based repository that contains information on the frequencies of immune-related genes and their corresponding alleles in worldwide human populations. At present, the system contains data from 1505 populations in more than ten million individuals on the ...
Faviel F. Gonzalez-Galarza, Derek Middleton, Gurpreet S. Ghattaoraya, Andrew R. Jones, Louise Y. Takeshita, Antony McCabe, Eduardo José Melo dos Santos   +6 more
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Estimating Allele Frequencies [PDF]

, 2011
Methods of estimating allele frequencies from data on unrelated and related individuals are described in this chapter. For samples of unrelated individuals with simple codominant markers, the natural estimator of allele frequencies can be used. For genetic data on related individuals, maximum likelihood estimation (MLE) can be applied to compute allele
Indra Adrianto, Courtney G. Montgomery
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Approaches to allele frequency determination [PDF]

Pharmacogenomics, 2000
Hundreds of thousands of candidate single nucleotide polymorphisms (SNPs) are being identified as part of the human genome project. For these markers to be useful in any study their allele frequencies in the study population must be known, or much effort will be wasted when markers with the wrong characteristics are selected for studies involving large-
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Frequency of Gc Alleles and a Variant Gc Allele in Iceland

Human Heredity, 1980
The gene frequency for Gc1 and Gc2 in an Icelandic population was found to be 0.71 and 0.29, respectively. An electrophoretic variant similar to Gc Norway was detected in 5 individuals of the same family. A pedigree of 14 family members, including two spouses, is presented.
Gudmundur Thordarson, Stefan Karlsson, Bjørnar Olaisen, Alfred Arnason   +3 more
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ALFRED: An allele frequency database for anthropology

American Journal of Physical Anthropology, 2002
AbstractThe deluge of data from the human genome project (HGP) presents new opportunities for molecular anthropologists to study human variation through the promise of vast numbers of new polymorphisms (e.g., single nucleotide polymorphisms or SNPs). Collecting the resulting data into a single, easily accessible resource will be important to facilitate
Michael V. Osier, Kenneth K. Kidd, Judith R. Kidd, Perry L. Miller, Kei-Hoi Cheung, Andrew J. Pakstis   +5 more
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Alpha thalassemia allelic frequency in Lebanon

Pediatric Blood & Cancer, 2014
BackgroundHemoglobinopathies are the most common reported monogenic disorders worldwide. It is well established that Mediterranean and Arab countries are high risk areas for thalassemia in general, and for alpha thalassemia in particular. Reports of alpha thalassemia gene mutations from the Lebanese population are limited.ProcedureWe investigated the ...
Ghassan Dbaibo, Hanine Ashkar, Miguel R. Abboud, Chantal Farra, Rebecca Badra, Ibrahim Dabbous, Samar Muwakkit, Carla Mounsef, Farah Fares   +8 more
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Allele frequencies with genic selection

Journal of Mathematical Biology, 1983
The structure of the limit point process of the ordered allele frequencies in the stationary distribution of a K-allele diffusion model with mutation and genic selection is studied. This leads to a formula for expectations of functions of the allele frequencies in terms of expectations in the neutral infinite alleles model.
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A note on the estimation of allele frequencies

American Journal of Physical Anthropology, 1973
AbstractA new method of obtaining allele frequency estimates is described. The method may prove useful when maximum likelihood estimates are not available. No assumptions regarding the absence of alleles are required. Errors of estimates have not been obtained, but the process seems to converge to maximum likelihood.
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The frequency of HLA alleles in the Romanian population

Immunogenetics, 2015
Knowledge of human leukocyte antigen (HLA) allele frequencies is essential for bone marrow and kidney donor searches. The Romanian Caucasian population is heterogeneous and information on HLA polymorphism has not been well studied. We characterized the HLA genetic profile and allele frequencies of regional populations in Romania.
Andrei-Antoniu Dinu, Voicu Boșcaiu, Mihaela Melinte, Elena Gai, Ana Moise, Petru Cianga, Ileana Constantinescu   +6 more
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D1S80 allele frequencies in a Chinese population

International Journal of Legal Medicine, 1994
Allele frequencies for the VNTR locus D1S80 were determined in a Chinese population sample using the polymerase chain reaction and subsequent analysis of the amplified products by polyacrylamide gel electrophoresis and silver staining. A total of 18 nominal D1S80 alleles were observed in 105 unrelated Chinese.
Ranajit Chakraborty, Bruce Budowle, Nu En Huang   +2 more
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