Results 31 to 40 of about 451,573 (269)

Forward-backward algorithms with a biallelic mutation-drift model: Orthogonal polynomials, and a coalescent/urn-model based approach [PDF]

arXiv, 2021
Inference of the marginal likelihood of sample allele configurations using backward algorithms yields identical results with the Kingman coalescent, the Moran model, and the diffusion model (up to a scaling of time). For inference of probabilities of ancestral population allele frequencies at any given point in the past - either of discrete ancestral ...
arxiv  

Exact Solution of the Multi-Allelic Diffusion Model [PDF]

Mathematical Biosciences (2007) v209 pp124-70, 2005
We give an exact solution to the Kolmogorov equation describing genetic drift for an arbitrary number of alleles at a given locus. This is achieved by finding a change of variable which makes the equation separable, and therefore reduces the problem with an arbitrary number of alleles to the solution of a set of equations that are essentially no more ...
arxiv   +1 more source

Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population

Hereditary Cancer in Clinical Practice, 2019
Background Large-scale case control studies revealed a number of moderate risk - low frequency breast cancer alleles of the PALB2 and RECQL genes. Some of these were reported as founder variants of Central and Eastern Europe.
Philip Hilz, Reicela Heinrihsone, Lukas Alexander Pätzold, Qi Qi, Genadijs Trofimovics, Linda Gailite, Arvids Irmejs, Janis Gardovskis, Edvins Miklasevics, Zanda Daneberga   +9 more
doaj   +1 more source

The sequential loss of allelic diversity [PDF]

Adv. Appl. Probab. 50 (2018) 13-29, 2018
This paper gives a new flavor of what Peter Jagers and his co-authors call `the path to extinction'. In a neutral population with constant size $N$, we assume that each individual at time $0$ carries a distinct type, or allele. We consider the joint dynamics of these $N$ alleles, for example the dynamics of their respective frequencies and more plainly
arxiv   +1 more source

Populational-genetic analysis of phenotype frequency of two qualitative properties of the tongue of the population of Zivinice [PDF]

Glasnik Antropološkog Društva Srbije, 2012
The objectives of this research were to establish the recessive phenotype frequency of the(in)ability of tongue rolling (fr) and frequency of the(in)ability of tongue folding. The data were collected by means of direct analysis and interviews with pupils
Hamidović Hajrija, Ahmić Adisa, Hadžiavdić Vesna   +2 more
doaj   +1 more source

Use of Microsatellites in Genetic Diversity Assessment, Parentage Testing and Individual Identification of the Kangal Shepherd Dog

Acta Veterinaria, 2020
The Kangal Shepherd Dog is considered the most common dog breed of Turkish origin. This study investigated variations in ten autosomal microsatellite markers (PEZ01, PEZ03, PEZ05, PEZ06, PEZ08, PEZ12, PEZ20, FHC2010, FHC2054 and FHC2079) for the purposes
Vladimir Dimitrijević, Marko Ristanić, Ljubodrag Stanisić, Darko Drobnjak, Milivoje Urosević, Umit Ozkanal, Zoran Stanimirović   +6 more
doaj   +1 more source

KRAS and GNAS mutations in cell‐free DNA and in circulating epithelial cells in patients with intraductal papillary mucinous neoplasms—an observational pilot study

Molecular Oncology, EarlyView.
This study demonstrates that KRAS and GNAS mutations are more prevalent in patients with resected intraductal papillary mucinous neoplasms (IPMN) compared to those under clinical surveillance. GNAS mutations significantly differ between the two patient cohorts, indicating that their absence may serve as a potential biomarker to support conservative ...
Christine Nitschke, Marie Tölle, Philipp Walter, Kira Meißner, Mara Goetz, Jolanthe Kropidlowski, Andreas W. Berger, Jakob R. Izbicki, Felix Nickel, Thilo Hackert, Klaus Pantel, Harriet Wikman, Faik G. Uzunoglu   +12 more
wiley   +1 more source

V-leaf marking in a Trifolium ambiguum Bieb. germplasm collection

Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 1987
Frequency values have been registered in the neomorph multiple allele series of V-leaf marking in a germplasm collection of Caucasian (Kura) clover - Trifolium ambiguum Bieb. This collection, obtained from the Northwest Reg. Plant Instr. Stn., Geneva N.Y.
Attila T. SZABO
doaj   +1 more source

On‐treatment dynamics of circulating extracellular vesicles in the first‐line setting of patients with advanced non‐small cell lung cancer: the LEXOVE prospective study

Molecular Oncology, EarlyView.
The LEXOVE prospective study evaluated plasma cell‐free extracellular vesicle (cfEV) dynamics using Bradford assay and dynamic light scattering in metastatic non‐small cell lung cancer patients undergoing first‐line treatments, correlating a ∆cfEV < 20% with improved median progression‐free survival in responders versus non‐responders.
Valerio Gristina, Viviana Bazan, Nadia Barraco, Simona Taverna, Mauro Manno, Samuele Raccosta, Anna Paola Carreca, Marco Bono, Tancredi Didier Bazan Russo, Francesco Pepe, Pasquale Pisapia, Lorena Incorvaia, Giuseppe Badalamenti, Giancarlo Troncone, Umberto Malapelle, Daniele Santini, Antonio Russo, Antonio Galvano   +17 more
wiley   +1 more source

Gene Frequency and Heritability of Rh Blood Group Gene in 44 Human Populations

Notulae Scientia Biologicae, 2010
The frequency of RhD and Rhd alleles of Rh blood group gene was estimated in 44 human populations distributed all over the world from the RhD phenotypic data.
Supriyo CHAKRABORTY
doaj   +3 more sources