Results 31 to 40 of about 595,057 (344)
ASAFE: ancestry-specific allele frequency estimation [PDF]
Bioinformatics, 2016 Abstract Summary: In a genome-wide association study (GWAS) of an admixed population, such as Hispanic Americans, ancestry-specific allele frequencies can inform the design of a replication GWAS. We derive an EM algorithm to estimate ancestry-specific allele frequencies for a bi-allelic marker given genotypes and local ancestries on a 3 ...
Qian S, Zhang +2 more
openaire +2 more sources
Indian Journal of Pathology and Microbiology, 2016 As the incidence of end-stage renal disease (ESRD) is rapidly increasing, the demand for dialysis and transplantation has dramatically increased, which has led to concerns about the availability and equitable allocation of kidneys for transplantation ...
Mohit Chowdhry +2 more
doaj +1 more source
The effect of recurrent mutations on genetic diversity in a large population of varying size [PDF]
, 2016 Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation.
Smadi, Charline
core +3 more sources
Genome-Wide Screening for SNPs Associated with Stature in Diverse Cattle Breeds
Biology and Life Sciences Forum, 2022 Cattle breeds used in industrial production tend to have a larger size compared to the local cattle, as the increased dairy and beef productivity is closely related to the stature. The aim of our work was to identify single nucleotide polymorphisms (SNPs)
Alexandra S. Abdelmanova +6 more
doaj +1 more source
Genetic diversity at the FMR1 locus in the Indonesian population [PDF]
, 2000 We report an analysis of allelic diversity at short tandem repeat polymorphisms within the fragile XA locus in 1069 male volunteers from twelve Indonesian sub-populations.
Buckley, Michael F +6 more
core +1 more source
Association of the leptin receptor Q223R (rs1137101) polymorphism with obesity measures in Sri Lankans [PDF]
, 2020 OBJECTIVE: The role of genetic factors in the development of obesity is largely unreported in Sri Lankans. The Q223R (rs1137101) single nucleotide polymorphism (SNP) of the leptin receptor (LEPR) gene has been associated with obesity measures in various ...
Dalton, C.F. +3 more
core +1 more source
Forbes Tıp DergisiObjective: Human leukocyte anti-gen (HLA) molecules are vital molecules because they present foreign anti-gens to immune cells and trigger the immune response.
Aslı ÖZKIZILCIK KOÇYİĞİT +6 more
doaj +1 more source
The prevalence and distribution of the amyloidogenic transthyretin (TTR) V122I allele in Africa [PDF]
, 2016 Transthyretin (TTR) pV142I (rs76992529-A) is one of the 113 variants in the human TTR gene associated with systemic amyloidosis. It results from a G to A transition at a CG dinucleotide in the codon for amino acid 122 of the mature protein (TTR V122I ...
Alexander, Alice A +10 more
core +1 more source
Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population
Hereditary Cancer in Clinical Practice, 2019 Background Large-scale case control studies revealed a number of moderate risk - low frequency breast cancer alleles of the PALB2 and RECQL genes. Some of these were reported as founder variants of Central and Eastern Europe.
Philip Hilz +9 more
doaj +1 more source
Shanghai yufang yixue, 2022 ObjectiveTo investigate the resistance to pyrethroids， beta-cyhalothrin and fenitrothion as well as the frequencies of kdr and ace⁃1 alleles in Anopheles sinensis from three geographical populations in Chongming District， Shanghai.MethodsThe contact ...
WEI Zixin +6 more
doaj +1 more source