Results 31 to 40 of about 5,554,112 (362)

3.5KJPNv2: an allele frequency panel of 3552 Japanese individuals including the X chromosome

open access: yesHuman Genome Variation, 2019
The first step towards realizing personalized healthcare is to catalog the genetic variations in a population. Since the dissemination of individual-level genomic information is strictly controlled, it will be useful to construct population-level allele ...
Shu Tadaka   +23 more
semanticscholar   +1 more source

Insecticide resistance and kdr , ace-1 allele mutations of Anopheles sinensis in Chongming District, Shanghai

open access: yesShanghai yufang yixue, 2022
ObjectiveTo investigate the resistance to pyrethroids, beta-cyhalothrin and fenitrothion as well as the frequencies of kdr and ace⁃1 alleles in Anopheles sinensis from three geographical populations in Chongming District, Shanghai.MethodsThe contact ...
WEI Zixin   +6 more
doaj   +1 more source

Human leukocyte antigen class I, class II, and tumor necrosis factor-alpha polymorphisms in a healthy elder Mexican Mestizo population [PDF]

open access: yes, 2005
BACKGROUND: There is strong evidence that an individual's genetic background is an important predisposing factor to longevity. In the present study we analysed the frequency of HLA class I, class II, as well as the TNF-α -308 polymorphism that may be ...
Llorente, Luis   +2 more
core   +3 more sources

Signatures of introgression across the allele frequency spectrum [PDF]

open access: yesMolecular Biology and Evolution, 2020
ABSTRCTThe detection of introgression from genomic data is transforming our view of species and the origins of adaptive variation. Among the most widely used approaches to detect introgression is the so-called ABBA BABA test orDstatistic, which identifies excess allele sharing between non-sister taxa.
Simon H. Martin, William Amos
openaire   +5 more sources

Allele Frequency Difference AFD–An Intuitive Alternative to FST for Quantifying Genetic Population Differentiation

open access: yesGenes, 2019
Measuring the magnitude of differentiation between populations based on genetic markers is commonplace in ecology, evolution, and conservation biology. The predominant differentiation metric used for this purpose is FST.
D. Berner
semanticscholar   +1 more source

Estimating the numbers of malaria infections in blood samples using high-resolution genotyping data [PDF]

open access: yes, 2012
People living in endemic areas often habour several malaria infections at once. High-resolution genotyping can distinguish between infections by detecting the presence of different alleles at a polymorphic locus.
Amanda Ross   +8 more
core   +7 more sources

Genetic polymorphisms of human platelet antigens in Euro-African and Japanese descendants from Parana, Southern Brazil

open access: yesPlatelets, 2017
The frequency distributions of HPA-1 to HPA-6 and HPA-15 were evaluated in two Brazilian populations from Parana: a mixed population of predominantly Caucasians and a population of Japanese descendants.
Ana Paula Avenia Silvestre   +4 more
doaj   +1 more source

Very low frequency of the lactase persistence allele LCT-13910T in the Armenian population

open access: yesAnnals of Human Biology, 2022
Primary lactose malabsorption is characterised by a down-regulation of lactase activity after weaning and inability to digest lactose in adulthood. It has been suggested that the historical introduction of dairying led to a positive selection for lactase
Stefan Németh   +5 more
doaj   +1 more source

Disparities in allele frequencies and population differentiation for 101 disease-associated single nucleotide polymorphisms between Puerto Ricans and Non-Hispanic Whites [PDF]

open access: yes, 2009
BACKGROUND. Variations in gene allele frequencies can contribute to differences in the prevalence of some common complex diseases among populations. Natural selection modulates the balance in allele frequencies across populations.
Adiconis, Xian   +9 more
core   +3 more sources

Estimation of allele frequencies at isoloci. [PDF]

open access: yesGenetics, 1988
Abstract In some polyploid animals and plants, pairs of duplicated loci occur that share alleles encoding proteins with identical electrophoretic mobilities. Except in cases where these "isoloci" are known to be inherited tetrasomically, individual genotypes cannot be determined unambiguously, and there is no direct way to assign ...
openaire   +3 more sources

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