Results 51 to 60 of about 595,057 (344)

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

The oestrogen receptor gene (ESR) PvuII polymorphism allele frequencies in Czech Large White and Landrace

Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis, 2005
Genotype and allele frequencies of the oestrogen receptor gene (ESR) PvuII restriction site were investigated in populations of the main Czech maternal breeds.
Eliška Goliášová, Josef Dvořák
doaj   +1 more source

Genomic polymorphism in tribal population of Tripura: Signifying their closer affinity with the Nepalese and Tibetan populations

Annals of Human Biology, 2021
Background India is the second most populous country in the world, which is aligned into various community segments. Aim To evaluate the genetic diversity of the tribal population of Tripura, we carried out this study.
Subhankar Nath, Pankaj Shrivastava, R. K. Kumawat, Shivani Dixit, Gyaneshwer Chaubey   +4 more
doaj   +1 more source

Qualitative mutant traits within the indigenous chicken population in selected ecological zones of Ghana

Scientific African, 2023
A study was carried out to find out the various mutant traits present in the indigenous chicken population and their influence on egg production in the three ecological zones of Ghana.
P. Mensah, K. Adomako, B.A. Hagan, J.A. Hamidu, S.O. Olympio   +4 more
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Properties of neutrality tests based on allele frequency spectrum [PDF]

, 2010
One of the main necessities for population geneticists is the availability of statistical tools that enable to accept or reject the neutral Wright-Fisher model with high power.
Ferretti, Luca, Marmorini, Giacomo, Ramos-Onsins, Sebastian   +2 more
core  

Rapid adaptation of a polygenic trait after a sudden environmental shift

, 2017
Although a number of studies have shown that natural and laboratory populations initially well-adapted to their environment can evolve rapidly when conditions suddenly change, the dynamics of rapid adaptation are not well understood.
Jain, Kavita, Stephan, Wolfgang
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

High-throughput estimation of allele frequencies using combined pooled-population sequencing and haplotype-based data processing

Plant Methods, 2022
Background In addition to heterogeneity and artificial selection, natural selection is one of the forces used to combat climate change and improve agrobiodiversity in evolutionary plant breeding. Accurate identification of the specific genomic effects of
Michael Schneider, Asis Shrestha, Agim Ballvora, Jens Léon   +3 more
doaj   +1 more source

Risk Allele Frequency Analysis of Single-Nucleotide Polymorphisms for Vitamin D Concentrations in Different Ethnic Group [PDF]

, 2021
Byung Woo Yoon, Hyun‐Tae Shin, Je Hyun Seo   +2 more
openalex   +1 more source