Results 51 to 60 of about 5,554,112 (362)

A Population Study: HLA-A, -B, -C, -DRB1, -DQB1, -DQA1 Alleles, and ABDR Haplotype Frequencies in the Aegean Region of Türkiye

Forbes Tıp Dergisi
Objective: Human leukocyte anti-gen (HLA) molecules are vital molecules because they present foreign anti-gens to immune cells and trigger the immune response.
Aslı ÖZKIZILCIK KOÇYİĞİT, Tülay KILIÇASLAN AYNA, Mustafa SOYÖZ, Burcu ÇERÇİ ALKAÇ, Rasime Derya GÜLEÇ, Deniz İlhan TOPÇU, İbrahim PİRİM   +6 more
doaj   +1 more source

Genetic diversity through human leukocyte antigen typing in end-stage renal disease patients and prospective donors of North India

Indian Journal of Pathology and Microbiology, 2016
As the incidence of end-stage renal disease (ESRD) is rapidly increasing, the demand for dialysis and transplantation has dramatically increased, which has led to concerns about the availability and equitable allocation of kidneys for transplantation ...
Mohit Chowdhry, Raj Nath Makroo, Manoj Kumar   +2 more
doaj   +1 more source

Evidence for selection on SARS-CoV-2 RNA translation revealed by the evolutionary dynamics of mutations in UTRs and CDSs

RNA Biology, 2022
RNA translation is the rate-limiting step when cells synthesize proteins. Elevating translation efficiency (TE) is intuitively beneficial. Particularly, when viruses invade host cells, how to compete with endogenous RNAs for efficient translation is a ...
Lin Zhu, Qi Wang, Weiyu Zhang, Hao Hu, Kexin Xu   +4 more
doaj   +1 more source

Minor allele frequency thresholds dramatically affect population structure inference with genomic datasets

bioRxiv, 2017
One common method of minimizing errors in large DNA sequence datasets is to drop variable sites with a minor allele frequency below some specified threshold.
E. Linck, C. Battey
semanticscholar   +1 more source

ALLELE FREQUENCIES IN MULTIGENE FAMILIES [PDF]

Journal of the Indonesian Mathematical Society, 2012
Results on allelle frequencies in three chromosomes, drawn at randomfrom a diploid population, evolving in equilibrium, at a particular generation, arepresented in this paper. The genes on each chromosome are subject to unbiased andreciprocal gene conversion and mutation.
openaire   +2 more sources

Use of Microsatellites in Genetic Diversity Assessment, Parentage Testing and Individual Identification of the Kangal Shepherd Dog

Acta Veterinaria, 2020
The Kangal Shepherd Dog is considered the most common dog breed of Turkish origin. This study investigated variations in ten autosomal microsatellite markers (PEZ01, PEZ03, PEZ05, PEZ06, PEZ08, PEZ12, PEZ20, FHC2010, FHC2054 and FHC2079) for the purposes
Vladimir Dimitrijević, Marko Ristanić, Ljubodrag Stanisić, Darko Drobnjak, Milivoje Urosević, Umit Ozkanal, Zoran Stanimirović   +6 more
doaj   +1 more source

Allelic variants of breast cancer susceptibility genes PALB2 and RECQL in the Latvian population

Hereditary Cancer in Clinical Practice, 2019
Background Large-scale case control studies revealed a number of moderate risk - low frequency breast cancer alleles of the PALB2 and RECQL genes. Some of these were reported as founder variants of Central and Eastern Europe.
Philip Hilz, Reicela Heinrihsone, Lukas Alexander Pätzold, Qi Qi, Genadijs Trofimovics, Linda Gailite, Arvids Irmejs, Janis Gardovskis, Edvins Miklasevics, Zanda Daneberga   +9 more
doaj   +1 more source

Heterogenous Distribution of MTHFR Gene Variants among Mestizos and Diverse Amerindian Groups from Mexico. [PDF]

PLoS ONE, 2016
Methylenetetrahydrofolate reductase (MTHFR) is a key enzyme in folate metabolism. Folate deficiency has been related to several conditions, including neural tube defects (NTDs) and cardiovascular diseases.
Cecilia Contreras-Cubas, Beatríz E Sánchez-Hernández, Humberto García-Ortiz, Angélica Martínez-Hernández, Francisco Barajas-Olmos, Miguel Cid, Elvia C Mendoza-Caamal, Federico Centeno-Cruz, Gabriela Ortiz-Cruz, José Concepción Jiménez-López, Emilio J Córdova, Eva Gabriela Salas-Bautista, Yolanda Saldaña-Alvarez, Juan Carlos Fernández-López, Osvaldo M Mutchinick, Lorena Orozco   +15 more
doaj   +1 more source

A Bayesian hierarchical model for allele frequencies [PDF]

Genetic Epidemiology, 2000
Genetic epidemiological methodologies, such as linkage analysis, often require accurate estimates of allele frequencies. When studies involve multiple sub-populations with different evolutionary histories, accurate estimates can be difficult to obtain because the number of subjects per sub-population tends to be limited.
Kathryn Roeder, John R. Lockwood, Bernie Devlin   +2 more
openaire   +3 more sources

THE REAL McCOIL: A method for the concurrent estimation of the complexity of infection and SNP allele frequency for malaria parasites

PLoS Comput. Biol., 2017
As many malaria-endemic countries move towards elimination of Plasmodium falciparum, the most virulent human malaria parasite, effective tools for monitoring malaria epidemiology are urgent priorities. P.
Hsiao-Han Chang, C. Worby, Adoke Yeka, J. Nankabirwa, M. Kamya, S. Staedke, G. Dorsey, M. Murphy, D. Neafsey, Anna E. Jeffreys, C. Hubbart, K. Rockett, R. Amato, D. Kwiatkowski, C. Buckee, B. Greenhouse   +15 more
semanticscholar   +1 more source