Results 61 to 70 of about 5,554,112 (362)
Systematic pan-cancer analysis of somatic allele frequency
Scientific Reports, 2018 Imbalanced expression of somatic alleles in cancer can suggest functional and selective features, and can therefore indicate possible driving potential of the underlying genetic variants.
Liam F. Spurr +11 more
semanticscholar +1 more source
V-leaf marking in a Trifolium ambiguum Bieb. germplasm collection
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 1987 Frequency values have been registered in the neomorph multiple allele series of V-leaf marking in a germplasm collection of Caucasian (Kura) clover - Trifolium ambiguum Bieb. This collection, obtained from the Northwest Reg. Plant Instr. Stn., Geneva N.Y.
Attila T. SZABO
doaj +1 more source
Populational-genetic analysis of phenotype frequency of two qualitative properties of the tongue of the population of Zivinice [PDF]
Glasnik Antropološkog Društva Srbije, 2012 The objectives of this research were to establish the recessive phenotype frequency of the(in)ability of tongue rolling (fr) and frequency of the(in)ability of tongue folding. The data were collected by means of direct analysis and interviews with pupils
Hamidović Hajrija +2 more
doaj +1 more source
Asymptotics of the allele frequency spectrum associated with the Bolthausen-Sznitman coalescent
, 2007 We work in the context of the infinitely many alleles model. The allelic partition associated with a coalescent process started from n individuals is obtained by placing mutations along the skeleton of the coalescent tree; for each individual, we trace ...
Basdevant, Anne-Laure +1 more
core +5 more sources
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Properties of neutrality tests based on allele frequency spectrum [PDF]
, 2010 One of the main necessities for population geneticists is the availability of statistical tools that enable to accept or reject the neutral Wright-Fisher model with high power.
Ferretti, Luca +2 more
core
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
The effect of recurrent mutations on genetic diversity in a large population of varying size [PDF]
, 2016 Recurrent mutations are a common phenomenon in population genetics. They may be at the origin of the fixation of a new genotype, if they give a phenotypic advantage to the carriers of the new mutation.
Smadi, Charline
core +3 more sources
Detecting Long-Term Balancing Selection Using Allele Frequency Correlation
bioRxiv, 2017 Balancing selection occurs when multiple alleles are maintained in a population, which can result in their preservation over long evolutionary time periods.
Katherine M. Siewert, B. Voight
semanticscholar +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source