Results 111 to 120 of about 880,277 (345)
On Wild-Type Iso-Alleles in Drosophila Melanogaster [PDF]
Curt Stern, Elizabeth White Schaeffer
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This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley +1 more source
Spatial and functional properties of pseudo-alleles at the white locus in Drosophila melanogaster [PDF]
M M Green
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Emerging Therapeutic Strategies for Hearing Loss
Challenges still exist in treating hearing loss in cases of severe damage to hair cells or spiral ganglion neurons. Here, a schematic diagram of cochlear sensory hair cells and auditory nerves is presented. It is found that in normal Corti organs, hair cells have upright stereocilia at the top and auditory neurons at the base. Ototoxic drugs, noise, or
Shanying Han+9 more
wiley +1 more source
GENIC ACTION AS STUDIED BY MEANS OF THE EFFECTS OF DIFFERENT DOSES AND COMBINATIONS OF ALLELES [PDF]
Curt Stern
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Based on a well‐established in vitro directed differentiation model and an integrated analysis of high‐density cell lineage trees (CLTs) and single‐cell transcriptomes, it is demonstrated that many subclones are formed by sub‐CLTs resembling each other in terms of both cell type compositions and topological structures.
Xiaoyu Zhang+14 more
wiley +1 more source
Genetic resources of local chicken in Georgia
The preservation of local poultry gene fund has both scientific and practical importance for Georgia. High genetic potential is important for breeders from national, state, scientific and economic points of view. It has been determined by scientists that
Anatoli Giorgadze, Marine Barvenashvili
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EFFECT OF THE DE17 ALLELE ON DEVELOPMENT OF THE MAIZE CARYOPSIS [PDF]
R. A. Brink, D. C. Cooper
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Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu+7 more
wiley +1 more source