Results 221 to 230 of about 870,271 (337)

Genetic Diversity and Selection of <i>MHC I-UAA</i> in Clariid Catfish from Thailand: Implications for Breeding and Conservation. [PDF]

Genes (Basel)
Nguyen THD, Chalermwong P, Patta C, Jaito W, Singchat W, Panthum T, Budi T, Sriphairoj K, Hatachote S, Srisapoome P, Muangmai N, Griffin DK, Antunes A, Duengkae P, Srikulnath K.   +14 more
europepmc   +1 more source

Complementation and recombination between Methionine-2 alleles in Neurospora crassa [PDF]

, 1960
Noreen E. Murray
openalex   +1 more source

A Refined Adaptive Laboratory Evolution Strategy With Biosensor‐Assisted Selection Resolves the Tolerance–Efficiency Trade‐Off in Toxic Chemical Biosynthesis

Advanced Science, EarlyView.
This study presents a refined adaptive laboratory evolution (ALE) strategy to resolve the trade‐off between tolerance and biosynthetic efficiency in toxic chemical production. Combining in vivo mutagenesis, microdroplet‐based evolution, and biosensor‐assisted selection, this strategy rapidly yields robust “win‐win” phenotypes.
Yufei Zhang, Junhua Yun, Guoyan Zhang, Hossain M. Zabed, Yuehui Tian, Xinrui Tang, Jia Li, Xianghui Qi   +7 more
wiley   +1 more source

Delineating the pathogenic threshold and phenotypic spectrum of SCA27B: findings from a large French-Canadian cohort. [PDF]

J Neurol
Iruzubieta P, Pellerin D, Ashton C, Villa F, Renaud M, Dicaire MJ, Danzi MC, Aldecoa M, Mathieu J, Massie R, Chalk CH, Lafontaine AL, Evoy F, Rioux MF, Brisson JD, Boycott KM, Houlden H, Synofzik M, La Piana R, Zuchner S, Duquette A, Brais B.   +21 more
europepmc   +1 more source

Homocysteine Exacerbates Pulmonary Fibrosis via Orchestrating Syntaxin 17 Homocysteinylation of Alveolar Type II Cells

Advanced Science, EarlyView.
The study identifies elevated homocysteine (Hcy) levels in idiopathic pulmonary fibrosis patients' samples, with alveolar type 2 cells as the primary site of Hcy metabolism. Methionine synthase reductase downregulation in these cells exacerbates fibrosis, while folate administration reduces Hcy levels and alleviates fibrosis.
Jiefeng Huang, Ke Fang, Wuyan Lu, Rongrong Wu, Yuanyuan Chen, Linxiao Li, Zihao Hu, Zixin Cai, Yu Jiang, Xinli Fan, Jinyi Deng, Guangpeng Liu, Zhuang Luo, Lei Cui, Shuaijun Li   +14 more
wiley   +1 more source

Resolving a century-old enigma: potato 'Bolters' originate from instability of the StCDF1.3 allele. [PDF]

Theor Appl Genet
Clot CR, van der Hulst RGM, van Eck HJ.
europepmc   +1 more source

Benchmarking Ploidy Estimation Methods for Bulk and Single‐Cell Whole Genome Sequencing

Advanced Science, EarlyView.
It comprehensively benchmarks computational tools for ploidy estimation from bulk and single‐cell whole‐genome sequencing data. The results highlight the strengths and limitations of each method under different conditions and identify PURPLE and SeCNV show top performance in bulk and single‐cell settings, respectively.
Yawei Song, Zilv Mei, Qijie Zheng, Qingqing Yuan, Yu Liang, Jiaqi Gao, Lang Zhou, Shuheng Wu, Wei Wu   +8 more
wiley   +1 more source

Polymorphism of <i>BoLA-DRB3</i> in Semen and Its Influence on Progeny Derived from Semen with Resistance and Susceptibility to Bovine Leukemia Virus Proviral Load. [PDF]

Pathogens
Bao A, Watanuki S, Matsuura R, Matsumoto Y, Wang J, Shimizu H, Niwano A, Kawata R, Aida Y.   +8 more
europepmc   +1 more source

AN ALLELE SPECIFIC AND A COMPLEMENTARY DETERMINANT CONTROLLING HOMOTHALLISM IN SACCHAROMYCES OVIFORMIS

, 1967
Isamu Takano, Yasuji Oshima
openalex   +2 more sources

IPGCA: A Comprehensive Single Cell Atlas of 1 074 127 Porcine Intestinal Cells Revealing Cellular Dynamics, Genetic Regulation, and Cross‐Species Conservation

Advanced Science, EarlyView.
A high resolution integrated cell atlas of the pig intestine provides insights into the genetic mechanisms of complex traits (Created in BioRender. Yu, P. (2025) https://BioRender.com/o14c563) Abstract The porcine intestinal tract is vital for nutrient absorption, immune regulation, and various physiological processes.
Pengfei Yu, Qinqin Xie, Xiaodian Cai, Zhanming Zhong, Ran Wei, He Han, Shuang Liu, Zhenyang Zhang, Lingyao Xu, Zitao Chen, Zhe Zhang, Qishan Wang, Yuchun Pan, Zhen Wang, Zhe Zhang   +14 more
wiley   +1 more source