Results 261 to 270 of about 870,271 (337)

mRNA Multipeptide-HLA Class II Immunotherapy for Melanoma. [PDF]

Cells
Georgopoulos AP, James LM, Sanders M.
europepmc   +1 more source

CSN6 Promotes Pancreatic Cancer Progression and Gemcitabine Resistance via Antagonizing DCAF1‐Mediated Ubiquitination of NPM1

Advanced Science, EarlyView.
COP9 signalosome subunit 6 (CSN6) promotes the auto‐ubiquitination and degradation of DDB1‐CUL4 associated factor 1 (DCAF1), thereby antagonizing DCAF1‐mediated ubiquitination of Nucleophosmin (NPM1). This stabilization of NPM1 enhances the ribosome biogenesis process and the translation of specific gemcitabine‐resistance proteins, ultimately driving ...
Yijing Zhang, Han Gao, Aiwen Tang, Haiwen Lyu, Zongmin Fan, Jiahui Guo, Yuzhi Wang, Hairong Yi, Qihao Pan, Haidan Luo, Baifu Qin, Boyu Zhang, Xiangqi Meng, Qingxin Liu, Mong‐Hong Lee   +14 more
wiley   +1 more source

Structure of a polymorphic repeat at the <i>CACNA1C</i> schizophrenia locus. [PDF]

Proc Natl Acad Sci U S A
Moya R, Wang X, Tsien RW, Maurano MT.
europepmc   +1 more source

THE METASTABLE NATURE OF PARAMUTABLE R ALLELES IN MAIZE. I. HERITABLE ENHANCEMENT IN LEVEL OF STANDARD Rr ACTION

, 1966
E. D. Styles, R. A. Brink
openalex   +2 more sources

Uric Acid Functions as an Endogenous Modulator of Microglial Function and Amyloid Clearance in Alzheimer's Disease

Advanced Science, EarlyView.
Higher serum UA levels are associated with reduced AD risk in epidemiological studies. UA enhances microglial phagocytic capacity primarily by restoring CD36 and TREM2 receptor recycling that is impaired by Aβ exposure. Therapeutically, UA supplementation improves cognitive function and reduces neuropathology in AD mouse model by enhancing microglial ...
De Xie, Qiuyang Zheng, Jiaming Lv, Qian Zhang, Zhiwei Cui, Shuai Huang, Wei Yu, Binyang Chen, Wanling Que, Shanpan Fu, Yuemei Xi, Jiayu Chen, Xueling Ye, Shuyi Chen, Hairong Zhao, Tetsuya Yamamoto, Hidenori Koyama, Xin Wang, Jidong Cheng   +18 more
wiley   +1 more source

SSR genotyping of 200 tea (Camellia sinensis) clones obtained by selection and DNA barcoding of 12 varietal registration candidates. [PDF]

BMC Plant Biol
Eminoğlu A, İzmirli ŞG, Beriş FŞ, Dinçer D, Yazıcı K.   +4 more
europepmc   +1 more source

B_x, Another Allele of the ABO Locus and its Heredity

, 1964
Hideo Yamaguchi, Yasuto Okubo, Fumio Hazama, Shizuo OYAMA   +3 more
openalex   +2 more sources

CDK4/6 Inhibitor Priming Enhances PD‐1 Blockade via Sellhi Neutrophil‐Induced Stat5a+ Progenitor Exhausted CD8+ T Cell

Advanced Science, EarlyView.
Activated tumor‐intrinsic cyclin D1‐CDK4/6 signaling attenuates lymphocyte infiltration, and consequently, and immunotherapy resistance in HNSCC. It is discovered that brief CDK4/6i priming before anti‐PD‐1 results in enhanced durability of ICB response durability through Stat5a+ progenitor exhausted CD8+ T cells induced by IL15‐secreted Sell(hi ...
Yu Zhang, Bao Sun, Rong Zhou, Zizhen Gong, Yong Han, Wenjie Tao, Chaoji Shi, Wuchang Zhang, Laikui Liu, Zhiyuan Zhang, Jiang Li, Qi Zhu, Weiwen Zhu, Ziyue Gu   +13 more
wiley   +1 more source

Interplay Between Genetic Diversity and Tree Vitality in <i>Fraxinus excelsior</i> Populations Affected by Ash Dieback. [PDF]

Genes (Basel)
Nowakowska J, Słowik J, Pacia A, Tereba A, Marozau A, Borowik P, Oszako T.   +6 more
europepmc   +1 more source

EFFECT OF A TRANSLOCATION IN MAIZE ON SENSITIVITY TO PARAMUTATION OF Rr ALLELES FROM THREE GEOGRAPHIC SOURCES

, 1965
R. A. Brink, J. Venkateswarlu
openalex   +2 more sources