Results 31 to 40 of about 1,221,818 (402)

Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori comprise two geographically widespread types, m1 and m2, and have evolved through limited recombination [PDF]

open access: yes, 1999
Vacuolating cytotoxin (vacA) alleles of Helicobacter pylori vary, particularly in their mid region (which may be type m1 or m2) and their signal peptide coding region (type s1 or s2).
Atherton, JC   +7 more
core   +1 more source

Sex-specific recombination rates and allele frequencies affect the invasion of sexually antagonistic variation on autosomes [PDF]

open access: yesJournal of Evolutionary Biology 26 (2013) 2428, 2013
The introduction and persistence of novel sexually antagonistic alleles can depend upon factors that differ between males and females. Understanding the conditions for invasion in a two-locus model can elucidate these processes. For instance, selection can act differently upon the sexes, or sex-linkage can facilitate the invasion of genetic variation ...
arxiv   +1 more source

RHD Positive Haplotype in D Negative Omani Blood Donor

open access: yesOman Medical Journal, 2023
The frequency of Rhesus D negative blood group in Omanis is 8.35% but the molecular background of this phenotype is unknown in the Omani population. The Rhesus D negative phenotype has a high molecular diversity.
Mujtaba Al Lawati, Badriya Al Balushi
doaj   +1 more source

Worldwide Distribution of Cytochrome P450 Alleles: A Meta‐analysis of Population‐scale Sequencing Projects

open access: yesClinical pharmacology and therapy, 2017
Genetic polymorphisms in cytochrome P450 (CYP) genes can result in altered metabolic activity toward a plethora of clinically important medications. Thus, single nucleotide variants and copy number variations in CYP genes are major determinants of drug ...
Yitian Zhou   +2 more
semanticscholar   +1 more source

S-Genotype Profiles of Turkish Apricot Germplasm

open access: yesNotulae Botanicae Horti Agrobotanici Cluj-Napoca, 2016
In flowering plants, gametophytic self-incompatibility, controlled by a single locus with several allelic variants, is one of the major problems preventing self-fertilization.
Kadir Ugurtan YILMAZ   +7 more
doaj   +1 more source

Novel alleles of rice eIF4G generated by CRISPR/Cas9‐targeted mutagenesis confer resistance to Rice tungro spherical virus

open access: yesPlant Biotechnology Journal, 2018
Summary Rice tungro disease (RTD) is a serious constraint in rice production across tropical Asia. RTD is caused by the interaction between Rice tungro spherical virus (RTSV) and Rice tungro bacilliform virus.
A. Macovei   +8 more
semanticscholar   +1 more source

Phenotypic continuum of NFU1‐related disorders

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 2025-2035, December 2022., 2022
Abstract Bi‐allelic variants in Iron–Sulfur Cluster Scaffold (NFU1) have previously been associated with multiple mitochondrial dysfunctions syndrome 1 (MMDS1) characterized by early‐onset rapidly fatal leukoencephalopathy. We report 19 affected individuals from 10 independent families with ultra‐rare bi‐allelic NFU1 missense variants associated with a
Rauan Kaiyrzhanov   +45 more
wiley   +1 more source

RECENT TECHNIQUES BASED ON THE UTILIZATION OF DNA AND AUTOSOMAL SINGLE NUCLEOTIDE POLYMORPHISMS FOR IDENTIFYING HUMANS

open access: yesGomal Journal of Medical Sciences, 2019
The biological samples used in forensics can contain DNA which is highly fragmented as a consequence of exposure to any of the numerous degrading factors.
Fahmida Khatoon
doaj   +1 more source

Polymorphism of the tumor necrosis factor beta gene in systemic lupus erythematosus [PDF]

open access: yes, 1993
We investigated the Nco I restriction fragment length polymorphism (RFLP) of the tumor necrosis factor beta (TNFB) gene in 173 patients with systemic lupus erythematosus (SLE), 192 unrelated healthy controls, and eleven panel families, all of German ...
Albert, E. D.   +6 more
core   +1 more source

A potential biomarker of cognitive impairment: The olfactory dysfunction and its genes expression

open access: yesAnnals of Clinical and Translational Neurology, Volume 9, Issue 12, Page 1884-1897, December 2022., 2022
Abstract Objective Accumulation evidence has reported that olfactory impairment may be an essential clinical marker and predictor of mild cognitive impairment or Alzheimer's disease. Method Participants were enrolled in the population‐based, prospective study in Fuxin county, Liaoning province, China between 2019 and 2021.
Jiayi Song   +11 more
wiley   +1 more source

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