Results 61 to 70 of about 870,271 (337)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

A rare case of aggressive, hereditary paraganglioma associated with a pathogenic variant in SDHD

Endokrynologia Polska, 2021
Not required for Clinical Vignette.
Anna Kurzyńska, Elwira Przybylik-Mazurek, Anna Skalniak, Monika Buziak-Bereza, Agata Brzozowska-Czarnek, Romana Tomaszewska, Alicja Hubalewska-Dydejczyk   +6 more
doaj   +1 more source

A Phylogenetic Analysis of the Genus Fragaria (Strawberry) Using Intron-Containing Sequence from the ADH-1 Gene [PDF]

, 2014
The genus Fragaria encompasses species at ploidy levels ranging from diploid to decaploid. The cultivated strawberry, Fragaria×ananassa, and its two immediate progenitors, F. chiloensis and F. virginiana, are octoploids.
Davis, Thomas M., DiMeglio, Laura M., Staudt, Gunter, Yu, Hongrun   +3 more
core   +1 more source

Allele Frequencies Database [PDF]

Transfusion Medicine and Hemotherapy, 2014
This review describes a database for the collection, archiving, sorting, searching and display of gene and allele frequencies for immunogenetic genes.
Faviel F. Gonzalez-Galarza, Louise Y. Takeshita, Andrew R. Jones, Derek Middleton   +3 more
openaire   +3 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

RECENT TECHNIQUES BASED ON THE UTILIZATION OF DNA AND AUTOSOMAL SINGLE NUCLEOTIDE POLYMORPHISMS FOR IDENTIFYING HUMANS

Gomal Journal of Medical Sciences, 2019
The biological samples used in forensics can contain DNA which is highly fragmented as a consequence of exposure to any of the numerous degrading factors.
Fahmida Khatoon
doaj   +1 more source

Mutation supply and the repeatability of selection for antibiotic resistance

, 2017
Whether evolution can be predicted is a key question in evolutionary biology. Here we set out to better understand the repeatability of evolution. We explored experimentally the effect of mutation supply and the strength of selective pressure on the ...
de Visser, J. Arjan G. M., Hwang, Sungmin, Krug, Joachim, van Dijk, Thomas, Zwart, Mark P.   +4 more
core   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

Contrasting patterns of spatial genetic differentiation in two east asian five-needle pine species, Pinus koraiensis and P. armandii [PDF]

Annals of Forest Research, 2008
Two species of East Asian five-needle pines of the section Strobus, Korean pine, Pinus koraiensis Sieb. et Zucc. and Armand's pine, Pinus armandii Franch are traditionally placed in two different subsections, Cembrae and Strobi, respectively.However ...
Belokon M.-M., Belokon Y.-S., Politov D.-V   +2 more
doaj  

Identification of intimin alleles in pathogenic Escherichia coli by PCR-restriction fragment length polymorphism analysis [PDF]

, 2008
A rapid two-step identification method based on PCR-RFLP analysis of the intimin gene was developed to differentiate specific alleles in pathogenic Escherichia coli.
Nebbia, Patrizia, Oswald, Eric, Robino, Patrizia, Tramuta, Clara   +3 more
core