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Journal of Allergy and Clinical Immunology, 2009
The question "What makes an allergen an allergen?" has puzzled generations of researchers, and we still do not have a conclusive answer. Despite increasing knowledge about the molecular and functional characteristics of allergens that have been identified, we still do not fully understand why some proteins are clinically relevant allergens and most are
Traidl-Hoffmann, Claudia +2 more
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The question "What makes an allergen an allergen?" has puzzled generations of researchers, and we still do not have a conclusive answer. Despite increasing knowledge about the molecular and functional characteristics of allergens that have been identified, we still do not fully understand why some proteins are clinically relevant allergens and most are
Traidl-Hoffmann, Claudia +2 more
openaire +4 more sources
The Function of Allergens May Determine Allergenicity
1996Allergenicity of an antigen in terms of Type-1 allergy has always been described as the ability of a given protein to bind to specific IgE antibodies and the potency of these allergens to crosslink cellbound IgE to induce mediator release like histamine in basophils or mast cells.
A, Bufe +4 more
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Allergens and Allergen Immunotherapy
1998Allergen immonotherapy in historical perpective definition of an allergen aerobiology allergen nomenclature tree pollen allergens grass pollen allergens weed pollen allergens mold allergens biting insect allergens mite allergens cockroach and other inhalent insect allergens food allergens latex allergens drug allergens, haptens and anaphylatoxins ...
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Current Allergy and Asthma Reports, 2005
Animal allergen exposure in early childhood and its relationship to the development of atopic disease is a subject that has been evolving rapidly. Recently, several well-designed studies have helped elucidate previous, often conflicting findings on this topic.
Megan Elizabeth, Partridge, Robert, Wood
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Animal allergen exposure in early childhood and its relationship to the development of atopic disease is a subject that has been evolving rapidly. Recently, several well-designed studies have helped elucidate previous, often conflicting findings on this topic.
Megan Elizabeth, Partridge, Robert, Wood
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Nature Ecology & Evolution, 2019
An assessment of the taxonomic composition of airborne pollen using targeted high-throughput sequencing may help in understanding environmental and human drivers of the grass pollen season and in allergy prevention and management.
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An assessment of the taxonomic composition of airborne pollen using targeted high-throughput sequencing may help in understanding environmental and human drivers of the grass pollen season and in allergy prevention and management.
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Current Allergy and Asthma Reports, 2002
Rodent allergens play a significant role in the pathogenesis of asthma and allergic rhinitis, and are potent causes of acute and chronic symptoms. This has long been apparent in occupational settings, particularly in the laboratory, but has been most recently studied and found to be important in home environments. These allergens have been suggested as
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Rodent allergens play a significant role in the pathogenesis of asthma and allergic rhinitis, and are potent causes of acute and chronic symptoms. This has long been apparent in occupational settings, particularly in the laboratory, but has been most recently studied and found to be important in home environments. These allergens have been suggested as
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Allergy, 2001
Most animal‐derived major allergens causing respiratory sensitization belong to the family of proteins called lipocalins. Their sequential identity varies but the three‐dimensional structure is conserved. They are present in body fluids and secretions. Several lipocalins are able to bind and transport small hydrophobic ligands like retinol.
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Most animal‐derived major allergens causing respiratory sensitization belong to the family of proteins called lipocalins. Their sequential identity varies but the three‐dimensional structure is conserved. They are present in body fluids and secretions. Several lipocalins are able to bind and transport small hydrophobic ligands like retinol.
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From Allergen Extracts to Allergen Genes and Allergen Molecules
2015An allergen is a type of protein capable of instructing the immune system to start producing IgE antibodies. The main purpose for determining the structure of major allergens is to analyze the exposed surface areas and to map the conformational epitopes. These can be determined by experimental methods including crystallographic and NMR-based approaches
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