Results 361 to 370 of about 258,969 (413)
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Allergy, allergens and allergen standardization
Medical Journal of Australia, 1984Immediate, type 1 allergic reactions occur following interaction between allergen, immunoglobulin E (IgE), and the mast cell or basophil. Allergen-induced activation of these cells leads to the release of a number of mediators that are responsible for the symptoms observed during an allergic reaction.
Brian A. Baldo, Euan R. Tovey
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Recombinant allergens/ allergen standardization
Current Allergy and Asthma Reports, 2001Recombinant allergens are genetically engineered isoforms representing allergen molecules from allergen extracts. Immunologic responses of allergic patients toward allergen extracts define the major allergens. For the average allergic patient, the diagnostic sensitivity and treatment efficacy correlate with the concentration of major allergen ...
Jørgen Nedergaard Larsen +1 more
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Association of asthma with serum IgE levels and skin-test reactivity to allergens.
New England Journal of Medicine, 1989We investigated the association of self-reported asthma or allergic rhinitis with serum IgE levels and skin-test reactivity to allergens in 2657 subjects in a general-population study. Regardless of the subjects' status with respect to atopy or their age
B. Burrows +4 more
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Clinical Reviews in Allergy & Immunology, 2001
What makes an antigen an allergen? This question has been at the core of much research regarding the basic mechanisms of allergy as well as the development of diagnostic and therapeutic allergen products. Great strides have been made since Kjell Aas asked this question in his classic review in Allergy (1), but we appear no closer to the answer.
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What makes an antigen an allergen? This question has been at the core of much research regarding the basic mechanisms of allergy as well as the development of diagnostic and therapeutic allergen products. Great strides have been made since Kjell Aas asked this question in his classic review in Allergy (1), but we appear no closer to the answer.
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Immunology and Allergy Clinics of North America, 2005
Exposure to allergens is a trigger for symptoms in sensitized individuals with asthma. This is especially true for allergens primarily found indoors but can be true for outdoor allergens with sufficiently high exposure. The role of allergens in attacks can be subtle in that they provide the underlying inflammation necessary for other nonspecific agents
Elizabeth A, Erwin +1 more
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Exposure to allergens is a trigger for symptoms in sensitized individuals with asthma. This is especially true for allergens primarily found indoors but can be true for outdoor allergens with sufficiently high exposure. The role of allergens in attacks can be subtle in that they provide the underlying inflammation necessary for other nonspecific agents
Elizabeth A, Erwin +1 more
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1998
Allergen exposure is a risk factor for sensitisation, prevalence and severity of allergic disease. Effective allergen avoidance strategies have been devised. The cost-benefit in public health terms should be established by prospective controlled studies that are under way around the world.
Custovic, A, Woodcock, A.
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Allergen exposure is a risk factor for sensitisation, prevalence and severity of allergic disease. Effective allergen avoidance strategies have been devised. The cost-benefit in public health terms should be established by prospective controlled studies that are under way around the world.
Custovic, A, Woodcock, A.
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Primary Care: Clinics in Office Practice, 1987
The environment contains a huge array of allergens, primarily proteins or glycoproteins, to which the atopic individual may become sensitized. In situations of high exposure and highly reactive substances, even nonatopic individuals may develop allergic antibodies.
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The environment contains a huge array of allergens, primarily proteins or glycoproteins, to which the atopic individual may become sensitized. In situations of high exposure and highly reactive substances, even nonatopic individuals may develop allergic antibodies.
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Allergen databases and allergen semantics
Regulatory Toxicology and Pharmacology, 2009The efficacy of any specific bioinformatic analysis of the potential allergenicity of new food proteins depends directly on the nature and content of the databases that are used in the analysis. A number of different allergen-related databases have been developed, each designed to meet a different need.
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Factors Influencing the Allergenicity and Adjuvanticity of Allergens
Immunotherapy, 2011IgE-mediated allergic disorders affect up to 25% of the population in industrialized countries and result in a Th2-polarized immune response to innocuous environmental proteins, so-called allergens. Among a large number of proteins to which humans are exposed to, only a minute fraction are allergens.
Stephan Deifl, Barbara Bohle
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2005
Allergy affects more than 25% of Western populations (1) and is estimated to be the sixth leading cause of chronic disease in the United States and Western Europe. The complexity of the condition is such that hundreds of common allergens have been described, and in order to maximize diagnostic efficiency there is an urgent clinical requirement for ...
Bacarese Hamilton T. +3 more
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Allergy affects more than 25% of Western populations (1) and is estimated to be the sixth leading cause of chronic disease in the United States and Western Europe. The complexity of the condition is such that hundreds of common allergens have been described, and in order to maximize diagnostic efficiency there is an urgent clinical requirement for ...
Bacarese Hamilton T. +3 more
openaire +5 more sources