Results 21 to 30 of about 143,532 (215)

Complements and allergic asthma

Pediatric Respirology and Critical Care Medicine, 2019
Regulatory T (Treg) cells play a central role in protecting against the development of allergic asthma and interleukin-10 (IL-10) producing T regulatory type 1 (Tr1) cells contribute to the regulation of asthma. Complement regulatory protein CD46 was shown to stimulate the development of IL-10 producing Tr1 cells.
Ching-Yuang Lin, Yi-Giien Tsai
openaire   +2 more sources

Early introduction of oats associated with decreased risk of persistant asthma and early introduction of fish with decreased risk of allergic rhinitis [PDF]

, 2010
The evidence of the effect of the age at introduction of new foods during infancy on the development of asthma and allergic rhinitis is inconsistent and scarce. We set out to study these associations.
Uusitalo U, Pirjo Pietinen, Virtanen SM, Riitta Veijola, Suvi M. Virtanen, Ilonen J, Uusitalo, Ulla, Kenward MG, Simell O, Kronberg-Kippilä C, Kronberg-Kippilä, Carina, Veijola R, Minna Kaila, Kaila, Minna, Olli Simell, Virtanen, Suvi M, Pietinen P, Ilonen, Jorma, Veijola, Riitta, Kenward, Michael G, Kaila M, Jorma Ilonen, Pietinen, Pirjo, Mikael Knip, Knip M, Knip, Mikael, Michael G. Kenward, Pekkanen, Juha, Juha Pekkanen, Ulla Uusitalo, Simell, Olli, Hakulinen, Timo, Pekkanen J, Timo Hakulinen, Hakulinen T, Carina Kronberg-Kippilä   +35 more
core   +1 more source

Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway

Frontiers in Immunology, 2019
IgE is secreted by plasma cells (PCs) and is central to allergic disease. Using an ex vivo tonsil B cell culture system, which mimics the Th2 responses in vivo, we have recently characterized the development pathway of human IgE-expressing PCs.
Faruk Ramadani, Faruk Ramadani, Holly Bowen, Holly Bowen, Hannah J. Gould, Hannah J. Gould, David J. Fear, David J. Fear   +7 more
doaj   +1 more source

Asthma and Allergic Inflammation [PDF]

Cell, 2010
Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of ...
openaire   +2 more sources

Overweight/obesity and respiratory and allergic disease in children: international study of asthma and allergies in childhood (ISAAC) phase two. [PDF]

, 2014
BACKGROUND: Childhood obesity and asthma are increasing worldwide. A possible link between the two conditions has been postulated. METHODS: Cross-sectional studies of stratified random samples of 8-12-year-old children (n = 10 652) (16 centres in ...
Forastiere, Francesco, Forastiere, F, Jaensch, A., Nagel, G, Jaensch Andrea, David P. Strachan, Gudrun Weinmayr (669480), Forastiere Francesco, Büchele Gisela, Strachan, D.P., Weinmayr, Gudrun, Gabriele Nagel (276147), Büchele, Gisela, Nagel, Gabriele, Gabriele Nagel, Jaensch, Andrea, Andrea Jaensch, Weinmayr Gudrun, Gisela Büchele, David P. Strachan (110302), Strachan, David P., Nagel Gabriele, Weinmayr, G, Strachan, DP, Andrea Jaensch (567644), Gudrun Weinmayr, Gisela Büchele (567645), David P Strachan, Weinmayr, G., Francesco Forastiere (669481), Strachan David P., ISAAC Phase Two Study Group, Büchele, G., Forastiere, F., Strachan, David P, Büchele, G, Jaensch, A, Francesco Forastiere, Nagel, G.   +38 more
core   +1 more source

The Endogenous Th17 Response in NO2-Promoted Allergic Airway Disease Is Dispensable for Airway Hyperresponsiveness and Distinct from Th17 Adoptive Transfer [PDF]

, 2013
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T., Weiss Daniel J., Laura Hoyt, Daggett, Rebecca, Alcorn John F., Poynter, ME, Daggett, R, Daggett Rebecca, Martin, Rebecca A., Lundblad Lennart K. A., Martin, RA, Daniel J. Weiss (460686), Ather Jennifer L., Lennart K. A. Lundblad (49082), Jennifer L. Ather (460682), Rebecca Daggett (460683), Alcorn, John F., Poynter, Matthew E., Hoyt Laura, Laura Hoyt (460684), John F. Alcorn (298001), Hoyt, L, Martin Rebecca A., Lennart K A Lundblad, Rebecca A Martin, Lundblad, Lennart K. A., Rebecca A. Martin (435571), Hoyt, Laura, Weiss, Daniel J., Poynter Matthew E., Rebecca Daggett, John F Alcorn, Alcorn, JF, Benjamin T Suratt, Suratt, BT, Ather, Jennifer L., Daniel J Weiss, Matthew E. Poynter (435575), Weiss, DJ, Lundblad, LKA, Jennifer L Ather, Benjamin T. Suratt (460685), Ather, JL, Chu, Hong Wei, Matthew E Poynter, Suratt Benjamin T.   +45 more
core   +1 more source

Methemoglobinemia during the Use of Glyceryl Trinitrate Patches in Neonates: Two Case Reports

American Journal of Perinatology Reports, 2018
Methemoglobinemia can result in severe hypoxia. It has been frequently reported during the use of inhaled nitric oxide, but can occur where nitrate containing medications are used.
Alison Mintoft, Emma Williams, Christopher Harris, Nigel Kennea, Anne Greenough   +4 more
doaj   +1 more source

Age-specific incidence of allergic and non-allergic asthma

BMC Pulmonary Medicine, 2020
Background Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was to assess age-specific incidence of
Johanna Pakkasela, Pinja Ilmarinen, Jasmin Honkamäki, Leena E. Tuomisto, Heidi Andersén, Päivi Piirilä, Hanna Hisinger-Mölkänen, Anssi Sovijärvi, Helena Backman, Bo Lundbäck, Eva Rönmark, Hannu Kankaanranta, Lauri Lehtimäki   +12 more
doaj   +1 more source

Self-Reported Truck Traffic on the Street of Residence and Symptoms of Asthma and Allergic Disease: A Global Relationship in ISAAC Phase 3 [PDF]

, 2009
BACKGROUND: Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries ...
H. Ross Anderson, Anderson, HR, Strachan, DP, Pearce, Neil, David P. Strachan, ISAAC Phase 3 Study Group, Christopher K.W. Lai, Anderson, H Ross, Lai, CK, Bert Brunekreef, Pearce, N, Stewart, AW, Neil Pearce, Stewart, Alistair W, ?, ?, Lai, Christopher KW, Strachan, David P, Lai, Christopher K W, Alistair W. Stewart, Brunekreef, B, Brunekreef, Bert   +20 more
core   +1 more source

Host lipidome analysis during rhinovirus replication in HBECs identifies potential therapeutic targets

Journal of Lipid Research, 2018
In patients with asthma or chronic obstructive pulmonary disease, rhinovirus (RV) infections can provoke acute worsening of disease, and limited treatment options exist.
An Nguyen, Anabel Guedán, Aurelie Mousnier, Dawid Swieboda, Qifeng Zhang, Dorottya Horkai, Nicolas Le Novere, Roberto Solari, Michael J.O. Wakelam   +8 more
doaj   +1 more source