Complements and allergic asthma
Regulatory T (Treg) cells play a central role in protecting against the development of allergic asthma and interleukin-10 (IL-10) producing T regulatory type 1 (Tr1) cells contribute to the regulation of asthma. Complement regulatory protein CD46 was shown to stimulate the development of IL-10 producing Tr1 cells.
Ching-Yuang Lin, Yi-Giien Tsai
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Risk factors for atopic and non-atopic asthma in a rural area of Ecuador [PDF]
Background: Asthma has emerged as an important public health problem of urban populations in Latin America. Epidemiological data suggest that a minority of asthma cases in Latin America may be associated with allergic sensitisation and that other ...
Oviedo, G +8 more
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Prevalence of Allergic and Non-allergic Asthma in Kumaun Region of Uttarakhand, India: A Cross-sectional Study [PDF]
Introduction: Asthma is a heterogenic disease, commonly divided into allergic and nonallergic asthma. It affects people of all age group and is associated with impaired lung function.
POONAM KUMARI +2 more
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Overweight/obesity and respiratory and allergic disease in children: international study of asthma and allergies in childhood (ISAAC) phase two. [PDF]
BACKGROUND: Childhood obesity and asthma are increasing worldwide. A possible link between the two conditions has been postulated. METHODS: Cross-sectional studies of stratified random samples of 8-12-year-old children (n = 10 652) (16 centres in ...
Forastiere, Francesco +39 more
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Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway
IgE is secreted by plasma cells (PCs) and is central to allergic disease. Using an ex vivo tonsil B cell culture system, which mimics the Th2 responses in vivo, we have recently characterized the development pathway of human IgE-expressing PCs.
Faruk Ramadani +7 more
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Asthma and Allergic Inflammation [PDF]
Studies of the initiation and maintenance of asthma and allergic inflammation implicate dysregulated interactions between mucosal epithelia and innate immune cells as the underlying cause of these disorders. The similarities of these responses with mucosal responses to parasitic intestinal worms may reveal pathways relevant to the perplexing rise of ...
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The Endogenous Th17 Response in NO
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T. +45 more
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Self-Reported Truck Traffic on the Street of Residence and Symptoms of Asthma and Allergic Disease: A Global Relationship in ISAAC Phase 3 [PDF]
BACKGROUND: Associations between traffic pollution on the street of residence and a range of respiratory and allergic outcomes in children have been reported in developed countries, but little is known about such associations in developing countries ...
H. Ross Anderson +20 more
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Methemoglobinemia during the Use of Glyceryl Trinitrate Patches in Neonates: Two Case Reports
Methemoglobinemia can result in severe hypoxia. It has been frequently reported during the use of inhaled nitric oxide, but can occur where nitrate containing medications are used.
Alison Mintoft +4 more
doaj +1 more source
Age-specific incidence of allergic and non-allergic asthma
Background Onset of allergic asthma has a strong association with childhood but only a few studies have analyzed incidence of asthma from childhood to late adulthood in relation to allergy. The purpose of the study was to assess age-specific incidence of
Johanna Pakkasela +12 more
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