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Allergic Bronchopulmonary Aspergillosis and Related Allergic Syndromes
While allergic bronchopulmonary aspergillosis (ABPA) is well recognized as a fungal complication of asthma, severe asthma with fungal sensitization (SAFS) is not.
David W. Denning
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International audienceA wide spectrum of pathological conditions may result from the interaction of Aspergillus fumigatus and the immune system of its human host.
Joana Vitte, Stéphane Ranque
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Allergic bronchopulmonary aspergillosis
Journal of Allergy and Clinical Immunology, 1984Allergic bronchopulmonary aspergillosis (ABPA) complicates asthma and cystic fibrosis. The survival factors in Aspergillus fumigatus that support saprophytic growth in bronchial mucus are not understood. Prednisone remains the most definitive treatment but need not be administered indefinitely.
A J, Ricketti +3 more
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Allergic Bronchopulmonary Aspergillosis
Clinics in Chest Medicine, 2012Allergic bronchopulmonary aspergillosis (ABPA) is caused by an exaggerated T(H)2 response to the ubiquitous mold Aspergillus fumigatus. ABPA develops in a small fraction of patients with cystic fibrosis and asthma, suggesting that intrinsic host defects play a major role in disease susceptibility.
Sonia N, Bains, Marc A, Judson
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Allergic Bronchopulmonary Aspergillosis
Chest, 2009Allergic bronchopulmonary aspergillosis (ABPA) is an immunologic pulmonary disorder caused by hypersensitivity to Aspergillus fumigatus. Clinically, a patient presents with chronic asthma, recurrent pulmonary infiltrates, and bronchiectasis. The population prevalence of ABPA is not clearly known, but the prevalence in asthma clinics is reported to be ...
T G, Radha, R, Viswanathan
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Allergic Bronchopulmonary Aspergillosis
CHEST Journal, 1985Allergic bronchopulmonary aspergillosis (ABPA) occurs as a complication of asthma. It presents as an infiltrative pulmonary disorder with respiratory and systemic symptoms, eosinophilia, elevated total serum IgE, and skin sensitizing, as well as precipitating antibodies to Aspergillus fumigatus. Sputum cultures are not always positive for the organism.
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Allergic Bronchopulmonary Aspergillosis
Clinics in Chest Medicine, 2022Allergic bronchopulmonary aspergillosis (ABPA) is a complex allergic disorder caused by immune reactions against Aspergillus fumigatus. ABPA most commonly complicates the course of patients with poorly controlled asthma. Patients commonly present with uncontrolled asthma, fleeting pulmonary opacities, and bronchiectasis.
Ritesh, Agarwal +5 more
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Allergic Bronchopulmonary Aspergillosis
Annual Review of Medicine, 1999Allergic bronchopulmonary aspergillosis (ABPA) is a syndrome seen in patients with asthma and cystic fibrosis. It is characterized by chronic colonization of the airways with a ubiquitous fungus, Aspergillus fumigatus. The clinical expression of ABPA results from the complex interaction of chronic colonization of the airways with A.
B A, Cockrill, C A, Hales
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Allergic Bronchopulmonary Aspergillosis
Proceedings of the American Thoracic Society, 2010Abstract Allergic bronchopulmonary aspergillosis (ABPA) is a complex clinical entity that results from an allergic immune response to Aspergillus fumigatus, most often occurring in a patient with asthma or cystic fibrosis. Sensitization to aspergillus in the allergic host leads to activation of T helper 2 lymphocytes, which play a key
Karen, Patterson, Mary E, Strek
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Allergic Bronchopulmonary Aspergillosis
Seminars in Respiratory and Critical Care Medicine, 2006Allergic bronchopulmonary aspergillosis is an uncommon but serious respiratory condition characterized by chronic airway inflammation and airway damage resulting from persistent colonization by and sensitization to the fungus Aspergillus fumigatus. The immunopathogenesis of allergic bronchopulmonary aspergillosis involves several pathways.
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