Results 21 to 30 of about 6,138 (136)

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

Allergy, EarlyView.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton, Manuel A. R. Ferreira, Wei Keat Lim, Carlo Sidore, Matthew F. Wipperman, Wenzhen Ge, Xue Song, Changming Xia, Julie E. Horowitz, Andrea T. Hooper, Sara C. Hamon, Jennifer Maloney, Jamie M. Orengo, Zhen Chen, Stephanie Amato Ricci, Bolanle Akinlade, Aris Baras, Gary Herman, Brandy L. Bennett, George D. Yancopoulos   +19 more
wiley   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

Allergy, EarlyView.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow, Xander Bertels, Vibeke Backer, Benjamin S. Bleier, Marco Caminati, Diego M. Conti, Eugenio De Corso, Mina Gaga, Valerie J. Lund, Corrado Pelaia, Anju T. Peters, Glenis K. Scadding, Martin Wagenmann, Riyad O. Al‐Lehebi, Guy G. Brusselle, Philippe Gevaert, Liam G. Heaney, Stella E. Lee, Florence Schleich, Frederik Trinkmann, Peter W. Hellings, Wytske J. Fokkens, Paola Rogliani   +22 more
wiley   +1 more source

Fighting diagnostic confirmation bias: Cystic fibrosis, allergic bronchopulmonary aspergillus, or both?

Clinical Case Reports, 2021
As diagnostic algorithms for cystic fibrosis (CF) continue to evolve, education of general practitioners is essential to prevent delayed diagnosis of CF and allow prompt referral to CF centers.
Patricia Choi, Laura Bauler, M. Myrtha Gregoire‐Bottex   +2 more
doaj   +1 more source

Therapeutic potential of a Bax inhibitor‐1/TMBIM6 antagonist (BIA) and its analogues in Aspergillus fumigatus‐induced asthma via dual targeting of AKT and epithelial‐derived inflammatory cytokines

British Journal of Pharmacology, EarlyView.
Background and Purpose Aspergillus fumigatus (A. fumigatus) exposure causes of severe allergic asthma, characterized by airway inflammation and epithelial dysfunction. TMBIM6 (Bax inhibitor‐1) has been implicated in airway epithelial stress responses and AKT signalling.
Young‐Jin Yu, Ahsan Ullah, Jisun Kim, Mehedi Hasan Bappi, Yerim Heo, Jin Hee Ahn, Hyun‐Kyoung Kim, Han‐Jung Chae   +7 more
wiley   +1 more source

T-cell epitope-based vaccine prediction against Aspergillus fumigatus: a harmful causative agent of aspergillosis

Journal of Genetic Engineering and Biotechnology, 2022
Background Among the most common causes of invasive aspergillosis and acute bronchopulmonary aspergillosis is Aspergillus fumigatus. Transmission with A.
Darakshan Jabin, Ajay Kumar
doaj   +1 more source

Bronchiectasis as an Underrecognized Extraintestinal Manifestation of Inflammatory Bowel Disease

JCC Plus, Volume 1, Issue 5, September 2026.
ABSTRACT Introduction Inflammatory bowel diseases (IBD) are chronic inflammatory diseases of the gastrointestinal tract, often presenting with extraintestinal manifestations (EIMs). The most prevalent pulmonary EIM is IBD‐associated bronchiectasis (IBD‐BE), which is often overlooked.
Lynn te Slaa, Josje Altenburg, Mark Löwenberg   +2 more
wiley   +1 more source

Allergic bronchopulmonary aspergillosis successfully treated with mepolizumab: Case report and review of the literature

Respiratory Medicine Case Reports, 2019
A 56-year-old woman was referred to our hospital for recurrent asthma of 20 years duration. She was diagnosed as having allergic bronchopulmonary aspergillosis on the basis of clinical symptoms, peripheral blood eosinophilia, elevated total serum ...
Shuko Hirota, Yoichi Kobayashi, Takashi Ishiguro, Takashi Nishida, Naho Kagiyama, Yoshihiko Shimizu, Noboru Takayanagi   +6 more
doaj   +1 more source

Methods for Determining the Number of Mold Fungi in the Air—Current Trends

Environmental Microbiology Reports, Volume 18, Issue 4, August 2026.
A unified methodological framework combining culture‐based, molecular, and data‐driven approaches to advance reliable measurement and interpretation of indoor fungal bioaerosols. ABSTRACT Indoor fungal contamination poses significant health concerns due to the diversity and dynamic behaviour of airborne spores.
Juhi Mishra, Wioletta Przystas
wiley   +1 more source

An unusual cause of hilar lymphadenopathy

Lung India, 2006
Allergic bronchopulmonary aspergillosis is an uncommon condition characterized by hypersensitivity to aspergillus antigen. It commonly presents as refractory asthma, fleeting pulmonary opacities and bronchiectasis.
Agarwal Ritesh, Reddy Chandana, Gupta D
doaj  

Pulmonary Aspergillus Nodule in an Immunocompetent Host: A Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Aspergillus is a common fungal pathogen that typically causes severe infections in patients with compromised immunity. This report explores a rare case of a pulmonary Aspergillus nodule in an immunocompetent person without underlying conditions. A 52‐year‐old man initially presented for evaluation of his son's allergic rhinitis, during which a
Ahmad Alikhani, Pooria Sobhanian, Mahla Hosseinzade, Shadi Shayesteh Azar, Farshad Naghshvar   +4 more
wiley   +1 more source