Results 51 to 60 of about 148,019 (190)

IL‐33 Drives Inflammatory Changes and Extracellular Trap Formation in Eosinophils Involving Oxidised LDL and Complement Pathways

open access: yesAllergy, Volume 81, Issue 9, Page 3171-3184, September 2026.
IL‐33 induces inflammatory gene signatures in eosinophils, characterised by the upregulation of cell surface markers, inflammatory mediators and regulatory factors, all of which were also observed in nasal polyp‐derived eosinophils. Ox‐LDL and complement fragments (C3a and C5a) promote eosinophil adhesion and survival.
Emiko Matsuyama   +16 more
wiley   +1 more source

Type‐2‐Inflammatory‐Diseases Share Comorbidities, Molecular Signatures, IL4/IL13 Genetics, and Response to IL4/IL13 Blockade

open access: yesAllergy, Volume 81, Issue 9, Page 3345-3360, September 2026.
Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton   +19 more
wiley   +1 more source

Impact of Aspergillus fumigatus in allergic airway diseases

open access: yesClinical and Translational Allergy, 2011
For decades, fungi have been recognized as associated with asthma and other reactive airway diseases. In contrast to type I-mediated allergies caused by pollen, fungi cause a large number of allergic diseases such as allergic bronchopulmonary mycoses ...
Chaudhary Neelkamal, Marr Kieren A
doaj   +1 more source

Remission in Global Airway Diseases: EUFOREA Consensus Paper

open access: yesAllergy, Volume 81, Issue 9, Page 3146-3156, September 2026.
ABSTRACT The therapeutic goal in chronic airway diseases is shifting from symptom control to disease remission. Disease‐modifying therapies, including biologics and allergen immunotherapy, have made remission achievable in patients with severe asthma, chronic rhinosinusitis with nasal polyps (CRSwNP), or allergic rhinitis (AR).
J. Christian Virchow   +22 more
wiley   +1 more source

Pediatric Pulmonary and Thoracic Aspergillosis

open access: yesSiriraj Medical Journal, 2020
Aspergillus infection can cause significant disease in an immunocompromised host and lungs are the most common site of infection. Various forms of aspergillus involving lung parenchyma have been described including aspergilloma, allergic bronchopulmonary
Preeyacha Pacharn   +3 more
doaj  

Lung and gut microbiomes in pulmonary aspergillosis: Exploring adjunctive therapies to combat the disease

open access: yesFrontiers in Immunology, 2022
Species within the Aspergillus spp. cause a wide range of infections in humans, including invasive pulmonary aspergillosis, chronic pulmonary aspergillosis, and allergic bronchopulmonary aspergillosis, and are associated with high mortality rates.
Liuyang Cai   +14 more
doaj   +1 more source

Inhaled N‐Acetylcysteine as a Potential Adjunctive Therapy in Mucus Plug‐Forming Asthma With Irpex lacteus Isolation: A Case Report

open access: yesRespirology Case Reports, Volume 14, Issue 8, August 2026.
A 68‐year‐old woman with mucus plug‐forming asthma and highly tenacious sputum received repeated administrations of inhaled N‐acetylcysteine, with subsequent rapid sputum improvement and radiographic resolution of mucus plugging. This case suggests that tenacious sputum may represent a treatable trait and that inhaled N‐acetylcysteine may serve as a ...
Yuka Uchida   +5 more
wiley   +1 more source

Methods for Determining the Number of Mold Fungi in the Air—Current Trends

open access: yesEnvironmental Microbiology Reports, Volume 18, Issue 4, August 2026.
A unified methodological framework combining culture‐based, molecular, and data‐driven approaches to advance reliable measurement and interpretation of indoor fungal bioaerosols. ABSTRACT Indoor fungal contamination poses significant health concerns due to the diversity and dynamic behaviour of airborne spores.
Juhi Mishra, Wioletta Przystas
wiley   +1 more source

Pulmonary Aspergillus Nodule in an Immunocompetent Host: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Aspergillus is a common fungal pathogen that typically causes severe infections in patients with compromised immunity. This report explores a rare case of a pulmonary Aspergillus nodule in an immunocompetent person without underlying conditions. A 52‐year‐old man initially presented for evaluation of his son's allergic rhinitis, during which a
Ahmad Alikhani   +4 more
wiley   +1 more source

Pulmonary Exacerbations and Treatment in PCD: A Narrative Review

open access: yesPediatric Pulmonology, Volume 61, Issue 7, July 2026.
ABSTRACT Primary ciliary dyskinesia (PCD) is a rare genetic disorder that causes chronic lung disease. Patients with PCD often experience pulmonary exacerbations with worsening symptoms and lung function decline. This review provides an overview of the existing knowledge regarding the PEx in PCD and reveals understudied topics that should be addressed ...
Pinelopi Anagnostopoulou   +3 more
wiley   +1 more source

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