Results 81 to 90 of about 5,211,261 (208)

Characterization of gut microbiota dynamics in an Alzheimer’s disease mouse model through clade-specific marker-based analysis of shotgun metagenomic data

Biology Direct
Alzheimer’s disease (AD) is a complex neurodegenerative disorder significantly impairing cognitive faculties, memory, and physical abilities. To characterize the modulation of the gut microbiota in an in vivo AD model, we performed shotgun metagenomics ...
Francesco Favero, Angela Re, Mohammed Salim Dason, Teresa Gravina, Mara Gagliardi, Marta Mellai, Marco Corazzari, Davide Corà   +7 more
doaj   +1 more source

Mastocytosis and allergic diseases.

Journal of investigational allergology & clinical immunology, 2014
Mastocytosis is a clonal disorder characterized by proliferation and accumulation of mast cells in various tissues, mainly skin and bone marrow. It can cause a wide variety of clinical manifestations-other than urticaria pigmentosa-that can lead to inappropriate release of mediators by mast cells. The most severe manifestation is anaphylaxis.
BONADONNA, PATRIZIA, Lombardo Carla, ZANOTTI, ROBERTA   +2 more
openaire   +2 more sources

Postpartum polymorphic eruption of pregnancy prominently occurring on striae distensae

Journal of Cutaneous Immunology and Allergy, 2022
Yasuaki Ogura, Manabu Inuzuka, Hiroki Morimoto, Masaki Otsuka, Yoshiki Tokura   +4 more
doaj   +1 more source

Bifunctional mesoporous glasses for bone tissue engineering: Biological effects of doping with cerium and polyphenols in 2D and 3D in vitro models

Biomaterials and Biosystems
This study evaluates the cytocompatibility of cerium-doped mesoporous bioactive glasses (Ce-MBGs) loaded with polyphenols (Ce-MBGs-Poly) for possible application in bone tissue engineering after tumour resection.
Ksenia Menshikh, Ajay Kumar Reddy, Andrea Cochis, Francesca Fraulini, Alfonso Zambon, Gigliola Lusvardi, Lia Rimondini   +6 more
doaj   +1 more source

Long-term periodic anthelmintic treatments are associated with increased allergen skin reactivity. [PDF]

, 2010
BACKGROUND: The low prevalence of allergic disease in the rural tropics has been attributed to the protective effects of chronic helminth infections. There is concern that treatment-based control programmes for these parasites may lead to an increase in ...
Oviedo, G, M. Vaca, I. Quinzo, L. C. Rodrigues, Rodriguez, A, Rodrigues, LC, Moncayo, A-L, M. E. Chico, Chico, ME, G. Oviedo, Lovato, R, Endara, P, P. J. Cooper, R. Lovato, M. L. Barreto, Quinzo, I, A.-L. Moncayo, P. Endara, Vaca, M, Erazo, S, A. Rodriguez, Barreto, ML, S. Erazo, Moncayo, AL, Cooper, PJ   +24 more
core   +1 more source

Probiotic detoxification of heavy metals: functional assessment in simulated intestinal and ex vivo models

Frontiers in Microbiology
IntroductionBioremediation is an emerging, sustainable strategy that relies on microbial processes to detoxify environmental pollutants. Among these pollutants, heavy metals (HMs) are pervasive, non-degradable toxic elements that pose serious risks to ...
Marco Pane, Annachiara De Prisco, Angela Amoruso, Giovanni Deusebio, Massimo Marzorati, Marco Corazzari, Romina Monzani, Valentina Saverio, Peter A. Bron   +8 more
doaj   +1 more source

Evidence of the efficacy and safety of house dust mite subcutaneous immunotherapy in elderly allergic rhinitis patients: a randomized, double-blind placebo-controlled trial

Clinical and Translational Allergy, 2017
Background Allergen specific immunotherapy (AIT) in elderly patients is controversial, and there is still little evidence supporting the safety and efficacy of this treatment in this population. The study objective was to evaluate the safety and efficacy
Andrzej Bożek, Krzysztof Kołodziejczyk, Renata Kozłowska, Giorgio Walter Canonica   +3 more
doaj   +1 more source

DNA‐based immunotherapeutics for the treatment of allergic disease

, 2001
Allergic diseases are a growing health concern in industrialized countries. Despite a number of effective therapeutic options for the prevention and treatment of the pathophysiologic responses which characterize allergic diseases, the induction of true ...
Raz, Eyal, Broide, David, Van Uden, John H., Horner, Anthony A., Zubeldia Ortuño, José Manuel   +4 more
core   +1 more source

Probiotic-derived extracellular vesicles: the next breakthrough in postbiotics for rheumatoid arthritis

Frontiers in Immunology
Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammation and joint damage. Emerging evidence highlights the role of gut and oral microbiota in RA pathogenesis, with microbial dysbiosis potentially exacerbating ...
Federica Dell’Atti, Federica Dell’Atti, Hugo Abreu, Hugo Abreu, Patrizia Malfa, Davide Raineri, Davide Raineri, Giuseppe Cappellano, Giuseppe Cappellano, Annalisa Chiocchetti, Annalisa Chiocchetti   +10 more
doaj   +1 more source

3D-printed β-TCP scaffold as a bone-mimicking environment for an engineered model of osteosarcoma: In vitro properties and transcriptomic insights

Materials Today Bio
In the face of advancements in osteosarcoma research, existing preclinical models – including in vitro (i.e., two- and three-dimensional cell cultures, organoids) and in vivo approaches (i.e., xenografts, animal models) – are often characterised by low ...
Ksenia Menshikh, Virginia Alessandra Gobbo, Mauro Nascimben, Markus Hannula, Andrea Cochis, Tiziano Serra, Jonathan Massera, Abhay Pandit, Lia Rimondini   +8 more
doaj   +1 more source