Results 31 to 40 of about 2,426,902 (210)

Mouse Model of Immune Complex-mediated Vasculitis in Dorsal Skin and Assessment of the Neutrophil-mediated Tissue Damage

Bio-Protocol, 2017
Neutrophils are the most abundant leukocytes in the blood. In the recent decades, their crucial roles in host defense, immune regulation and tissue damage have been studied in a deeper dimension.
Dongsheng Jiang, Juliane de Vries, Jana Muschhammer, Anca Sindrilaru, Karin Scharffetter-Kochanek   +4 more
doaj   +1 more source

Length of hospital stay and survival of hospitalized COVID-19 patients during the second wave of the pandemic: A single centre retrospective study from Slovenia

Slovenian Journal of Public Health, 2022
As of writing, there are no publications pertaining to the prediction of COVID-19-related outcomes and length of stay in patients from Slovene hospitals.
Rozman Aleš, Rituper Boštjan, Kačar Mark, Kopač Peter, Zidarn Mihaela, Pohar Perme Maja   +5 more
doaj   +1 more source

Cell death in allergic diseases [PDF]

, 2009
Apoptosis, the most common form of cell death, is a key mechanism in the build up and maintenance of both innate and adaptive immunity. Central to the apoptotic process is a family of intracellular cysteine proteases with aspartate-specificity, called ...
Simon, Hans-Uwe
core   +2 more sources

JTE-013 Alleviates Pulmonary Fibrosis by Affecting the RhoA/YAP Pathway and Mitochondrial Fusion/Fission

Pharmaceuticals, 2023
Pulmonary fibrosis may be due to the proliferation of fibroblasts and the aggregation of extracellular matrix, resulting in the stimulation of inflammation damage, destroying lung tissue structure, seriously affecting the patient’s respiratory function ...
Jiaxu Zhou, Yilan Song, Xingmei Wang, Xinrui Li, Chang Liu, Chenchen Tian, Chongyang Wang, Liangchang Li, Guanghai Yan, Hong Cui   +9 more
doaj   +1 more source

Allergic diseases in the elderly

Translational Medicine @ UniSa
Recent increases in allergic diseases are thought to be caused by better hygiene, Westernized diets, air pollution, climate change, and other factors that influence host microbiota, a key player in the induction and maintenance of immunoregulatory circuits and tolerance.
Di Lorenzo, Gabriele, Melluso, Marcello, Rodolico, Alessandro, Seidita, Aurelio   +3 more
openaire   +4 more sources

Tregs and allergic disease [PDF]

Journal of Clinical Investigation, 2004
Allergic diseases such as asthma, rhinitis, and eczema are increasing in prevalence and affect up to 15% of populations in Westernized countries. The description of Tregs as T cells that prevent development of autoimmune disease led to considerable interest in whether these Tregs were also normally involved in prevention of sensitization to allergens ...
Douglas S, Robinson, Mark, Larché, Stephen R, Durham   +2 more
openaire   +2 more sources

Evidence for a modulatory effect of IL-10 on both Th1 and Th2 cytokine production: the role of the environment. [PDF]

, 2011
Allergic and other immune-mediated diseases are complex disease states determined by interplay between host genetics and environmental factors. Environmental changes such as fewer infections and reduced exposure to microbial products have been suggested ...
Pontes-de-Carvalho, Lain Carlos, Cooper, Philip J, Figueiredo, Camila A., Neuza M. Alcantara-Neves, Laura C. Rodrigues, Figueiredo, Camila A, Nivea B. Silva, Silva, Nivea B., Amorim, Leila D., Barreto, Maurício Lima, Amorim, Leila D, Barreto, Maurício L., Barreto, Maurício L, Philip J. Cooper, Alcantara-Neves, Neuza M., Carvalho, Lain C Pontes de, Neves, Neuza Maria Alcântara, Cooper, Philip John, Maurício L. Barreto, Alcantara-Neves, Neuza M, Pontes de Carvalho, Lain C., Cooper, Philip J., Figueiredo, Camila Alexandrina Viana, Rodrigues, Laura C., Camila A. Figueiredo, Silva, Nivea B, Rodrigues, Laura C, Leila D. Amorim, Rodrigues, Laura Cunha, Lain C. Pontes de Carvalho   +29 more
core   +1 more source

Immune and allergic responses to Anisakis pegreffii, with focus on the roles of IL-4, IL-13 and the IL-4 receptor alpha [PDF]

, 2007
Includes bibliographical references (p. 117-127).The fish-parasitizing nematode Anisakis pegreffii induces gastrointestinal disease and allergy when ingested by humans, and can cause occupational allergy in seafood processing workers.
Nieuwenhuizen, Natalie
core   +1 more source

Combining Biologics Targeting Eosinophils (IL-5/IL-5R), IgE, and IL-4/IL-13 in Allergic and Inflammatory Diseases

World Allergy Organization Journal, 2022
The indications for biologic therapy are expanding. Patients may benefit from different biologics for separate conditions or one condition with multiple pathogenic mechanisms targeted by different biologics.
Mitchell M. Pitlick, MD, Thanai Pongdee, MD   +1 more
doaj   +1 more source

Temporal Changes in Total Serum Immunoglobulin E Levels in East German Children and the Effect of Potential Predictors [PDF]

, 2012
Background: Elevated total serum immunoglobulin E (IgE) levels are a prominent feature of allergic and parasitic diseases. An epidemiologic study was conducted in East German children to describe trends in the development of total serum IgE levels and ...
Wichmann, Heinz-Erich, Rzehak, Peter, Heinrich, Joachim, Wichmann, H.-E., Thiering, Elisabeth, Thiering, E., Brüske, Irene, Rzehak, P., Flohrs, K., Flohrs, Katrin, Heinrich, J., Brüske, I.   +11 more
core   +1 more source