Results 51 to 60 of about 2,426,902 (210)

Oncogenic D816V-KIT signaling in mast cells causes persistent IL-6 production

open access: yesHaematologica, 2020
Persistent dysregulation of IL-6 production and signaling have been implicated in the pathology of various cancers. In systemic mastocytosis, increased serum levels of IL-6 associate with disease severity and progression, although the mechanisms involved
Araceli Tobío   +9 more
doaj   +1 more source

Comparison of the Concordance of Allergic Diseases between Monozygotic and Dizygotic Twins: A Cross-Sectional Study Using KoGES HTS Data

open access: yes, 2023
Several epidemiological studies have demonstrated that genetic and environmental factors contribute to the development of allergic diseases. However, there is limited information on these factors in the Korean population.
Hyun Lim   +10 more
core   +1 more source

Fibulin-3 in plasma and pleural effusion as a biomarker of mesothelioma

open access: yesRadiology and Oncology
Malignant pleural mesothelioma (MPM) is a global health concern linked to asbestos exposure. In Slovenia, regions with high asbestos exposure rates make MPM a significant public health issue.
Adamic Katja   +3 more
doaj   +1 more source

The effects of anti-sense interleukin-5 gene transferred by recombinant adeno-associated virus in allergic rats [PDF]

open access: yes, 2008
The accumulation and infiltration of eosinophils in airways is one of the most important characteristics of asthma, and is mediated partly by secretion of IL-5 from Th2 lymphocytes.
Weining Xiong   +6 more
core  

Paediatric cervicofacial lymphadenitis caused by non-tuberculous mycobacteria: nation-wide overview in the period 2000–2020

open access: yesBMC Pediatrics
Purpose Cervicofacial lymphadenitis caused by non-tuberculous mycobacteria (NTM) is a rare but increasing infection in children worldwide. The purpose of this study was to analyse and evaluate all microbiologically proven cases of NTM lymphadenitis in ...
Eva Sodja   +4 more
doaj   +1 more source

Impact of a digital web-based asthma platform, a real-life study

open access: yesBMC Pulmonary Medicine, 2023
Background Digital health technology (DHT) is a growing area in the treatment of chronic diseases. Study results on DHT’s effect on asthma control have been mixed, but benefits have been seen for adherence, self-management, symptoms, and quality of life.
Emma M. Genberg   +4 more
doaj   +1 more source

Research needs in allergy: an EAACI position paper, in collaboration with EFA [PDF]

open access: yes, 2012
In less than half a century, allergy, originally perceived as a rare disease, has become a major public health threat, today affecting the lives of more than 60 million people in Europe, and probably close to one billion worldwide, thereby heavily ...
Mingomataj, Ervin
core   +1 more source

The Endogenous Th17 Response in NO2-Promoted Allergic Airway Disease Is Dispensable for Airway Hyperresponsiveness and Distinct from Th17 Adoptive Transfer [PDF]

open access: yes, 2013
Severe, glucocorticoid-resistant asthma comprises 5-7% of patients with asthma. IL-17 is a biomarker of severe asthma, and the adoptive transfer of Th17 cells in mice is sufficient to induce glucocorticoid-resistant allergic airway disease.
Suratt, Benjamin T.   +45 more
core   +2 more sources

Patients with detectable KIT p.D816V in peripheral blood are at high risk for adverse systemic events during venom immunotherapy and treatment failure

open access: yesClinical and Translational Allergy
Background Recent studies have highlighted the importance of routine screening for the somatic missense KIT p.D816V variant in peripheral blood leukocytes (PBL), and its association with severe sting anaphylaxis.
Ajda Demšar Luzar   +6 more
doaj   +1 more source

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