American Journal of Hematology, EarlyView.ABSTRACT Sutimlimab is a monoclonal antibody against complement fraction C1s approved for the treatment of hemolytic anemia due to cold agglutinin disease (CAD). Here, we analyzed and report the largest international CAD cohort of sutimlimab‐treated patients ever reported to highlight its safety and effectiveness in the real‐world setting. We accrued a
Bruno Fattizzo +38 more
wiley +1 more source
Correction: Therapeutic DNA vaccine attenuates itching and allergic inflammation in mice with established biting midge allergy. [PDF]
PLoS OneLee MF, Chen YH, Song PP, Lin TM.
europepmc +1 more source
American Journal of Hematology, EarlyView.ABSTRACT Renal impairment (RI), defined as estimated glomerular filtration rate less than 60 mL/min with or without the need for dialysis, is a frequent and severe complication in patients with relapsed/refractory multiple myeloma (RRMM), as it can affect patient prognosis, drug metabolism and treatment options.
Ioannis Ntanasis‐Stathopoulos +7 more
wiley +1 more source
Epidermal RORα Maintains Barrier Integrity and Prevents Allergic Inflammation by Regulating Late Differentiation and Lipid Metabolism. [PDF]
Int J Mol SciHua X, Ficaro MK, Wallace NL, Dai J.
europepmc +1 more source
A Novel Plasma Heme Assay Reveals Disease Severity in Beta‐Thalassemia and Sickle Cell Anemia
American Journal of Hematology, EarlyView.ABSTRACT Anemia results from imbalanced hemoglobin or red blood cell production and clearance. Hemolytic anemia, caused by premature red blood cell removal, can be intravascular (in blood) or extravascular (erythrophagocytosis). Hemolysis is common in Sickle Cell Disease (SCD) and Beta‐Thalassemia anemia (β‐thalassemia), the most prevalent inherited ...
Laurent Kiger +14 more
wiley +1 more source
Effect of Air Pollutants on Allergic Inflammation in Structural Cells of the Nasal Mucosa. [PDF]
Clin Exp OtorhinolaryngolPark JH +4 more
europepmc +1 more source
Circulating Tumor Cells in Multiple Myeloma: From Peripheral Clues to Central Insights
American Journal of Hematology, EarlyView.CTC offer a minimally invasive widow into systemic myeloma biology, overcoming the sampling bias of bone marrow biopsies. Their prognostic value at diagnosis, potential role in MRD monitoring, and ability to capture clonal evolution highlight them as actionable biomarkers for future precision medicine.
Benjamin Podvin +3 more
wiley +1 more source
Intranasal Application of Foxp3 Introduced with Poly(d,l-lactic-<i>co</i>-glycolic acid) (PLGA) Nanoparticles (Foxp3 NPs) Attenuates Allergic Inflammation in a Mouse Model of Allergic Rhinitis. [PDF]
PharmaceuticsHan SC, Yeon S, Kim H, Park S.
europepmc +1 more source