Results 121 to 130 of about 164,503 (308)

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

open access: yesAdvanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu   +14 more
wiley   +1 more source

Allergic reaction to peripheral nerve stimulator

open access: yes, 2012
Objective: Pain physicians should be aware of a rare but possible complication associated with the use of pe-ripheral nerve stimulation. While pacemaker dermatitis and allergic reactions to a spinal cord stimulator have been recog-nized, there have been ...
Schaffner, R.   +3 more
core  

Canagliflozin Alleviates Diabetic Glomerular Endothelial Injury via Melibiose in a Microbiota‐Dependent Manner

open access: yesAdvanced Science, EarlyView.
Canagliflozin treatment reshapes the gut microbiota in DKD and elevates levels of melibiose, a metabolite derived from Roseburia intestinalis. Melibiose directly binds to and enhances the enzymatic activity of glyoxalase 1, leading to decreased methylglyoxal accumulation.
Wei Zhang   +32 more
wiley   +1 more source

Peran Kemokin dalam Patogenesis Rinitis Alergi

open access: yesJurnal Kesehatan Andalas, 2014
AbstrakLatar belakang: Rinitis alergi merupakan penyakit dengan insiden yang cukup tinggi diseluruh dunia dengan prevalensi yang semakin meningkat setiap tahun. Patogenesis rinitis alergi melibatkan reaksi imun yang cukup komplek.
Effy Huriyati   +2 more
doaj  

Novel foods and food allergies : an exploratory study of novel foods as allergy management strategy

open access: yes, 2009
Food allergy represents an increasing concern to society. It is defined as an inappropriate immunological reaction to normally harmless food components and affects 5-8% of children and 1-2% of adults. Since at the time of writing no cure for food allergy
Putten, M.C., van
core  

Allergic Reaction to Antipyrine, A Marker of Hepatic Enzyme Activity

open access: yes, 1989
Antipyrine is a pyrazole derivative used extensively as a marker for hepatic drug metabolizing enzyme activity. A subject participating in a clinical trial employing antipyrine experienced an acute allergic reaction to the drug which was characterized ...
Peter H. Vlasses   +2 more
core   +1 more source

Sex‐Specific Regulation of Glycemic Homeostasis by Theabrownin from Pu‐erh Tea

open access: yesAdvanced Science, EarlyView.
Pu‐erh tea's key component, theabrownin (TB), lowers blood glucose in a sex‐specific manner. In females, estrogen boosts intestinal MUC2 production, which dramatically enhances TB's ability to inhibit the carbohydrate‐digesting enzyme α‐glucosidase.
Yang Li   +22 more
wiley   +1 more source

Severe quadriparesis caused by wasp sting

open access: yesThe Turkish Journal of Pediatrics, 2009
Besides the typical symptoms of allergic reaction after wasp sting, unusual and unexpected reactions may also develop. In this report, a case of severe peripheral quadriparesis and sphincteric disorder (urinary incontinence) in a 10-year-old boy ...
Peter Bánovcin   +6 more
doaj  

Economic considerations in the treatment of systemic allergic reactions

open access: yes, 2018
Emma Westermann-Clark,1,2 Amber N Pepper,1,2 Richard F Lockey1,2 1Division of Allergy and Immunology, Department of Internal Medicine, University of South Florida Morsani College of Medicine, 2James A.
Lockey RF, Westermann-Clark E, Pepper AN
core  

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

open access: yesAdvanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan   +12 more
wiley   +1 more source

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