Results 1 to 10 of about 4,063,072 (347)

Prion Disease and the Innate Immune System [PDF]

Viruses, 2012
Prion diseases or transmissible spongiform encephalopathies are a unique category of infectious protein-misfolding neurodegenerative disorders. Hypothesized to be caused by misfolding of the cellular prion protein these disorders possess an infectious ...
Akira, Ansel, Aucouturier, Baker, Baker, Baker, Barry Bradford, Bartz, Beaulieu, Beekes, Bergtold, Bessen, Blanquet-Grossard, Bruce, Bueler, Burwinkel, Chesebro, Colten, Colten, Cordier-Dirikoc, Cordier-Dirikoc, Cunningham, de Almeida, Dieu, Erblich, Flores-Langarica, Ford, Fraser, Fraser, Fritz, Fu, Gilch, Glaysher, Hamilton, Heppner, Hosszu, Houston, Hunter, Jonjić, Kim, Kimberlin, Kimberlin, Klein, Klein, Kopacek, Kujala, Le, Le, Levavasseur, Li, Liu, Loeuillet, Lu, Luhr, Luhr, Lunnon, Mabbott, Mabbott, Manson, Marella, Marijanovic, Martinez del Hoyo, Mathiason, McCulloch, McCutcheon, Miragliotta, Mitchell, Mohan, Mok, Moore, Neil Mabbott, Oldstone, Opalinska, Paquet, Parkin, Piercey Åkesson, Prinz, Prinz, Prinz, Prusiner, Raymond, Raymond, Raymond, Rescigno, Riemer, Riemer, Riemer, Robertson, Rosicarelli, Rybner, Rybner-Barnier, Saba, Sassa, Schwaeble, Sein, Sethi, Shanas, Silver, Teh, Thackray, Uraki, Uraki, Veerhuis, Walsh, Wang, Wathne, Williams, Xiang, Yadavalli, Yanamadala, Zabel   +110 more
core   +7 more sources

Immune System and Chronic Diseases [PDF]

Journal of Immunology Research, 2017
Margarete Dulce Bagatini, Andréia Machado Cardoso, Alessandra Antunes dos Santos, Fabiano Barbosa Carvalho   +3 more
doaj   +3 more sources

Neutrophil to Lymphocyte Ratio: An Emerging Marker of the Relationships between the Immune System and Diseases

International Journal of Molecular Sciences, 2022
Over the last 10 years, the evaluation of the neutrophil-to-lymphocyte ratio (NLR) as an emerging marker of diseases has become a compelling field of bio-medical research.
Agata Buonacera, B. Stancanelli, M. Colaci, L. Malatino   +3 more
semanticscholar   +1 more source

SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain

Communications Biology, 2023
The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions.
Jiansheng Jiang, Christopher T. Boughter, Javeed Ahmad, Kannan Natarajan, Lisa F. Boyd, Martin Meier-Schellersheim, David H. Margulies   +6 more
doaj   +1 more source

The Interplay between the Gut Microbiome and the Immune System in the Context of Infectious Diseases throughout Life and the Role of Nutrition in Optimizing Treatment Strategies

Nutrients, 2021
Infectious diseases and infections remain a leading cause of death in low-income countries and a major risk to vulnerable groups, such as infants and the elderly. The immune system plays a crucial role in the susceptibility, persistence, and clearance of
S. Wiertsema, J. van Bergenhenegouwen, J. Garssen, L. Knippels   +3 more
semanticscholar   +1 more source

Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways

Scientific Data, 2022
Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes, Jessica M. Calzola, Pauline R. Kaplan, Iain D. C. Fraser, Ronald N. Germain, Martin Meier-Schellersheim, Aleksandra Nita-Lazar   +6 more
doaj   +1 more source

An Update on the Effects of Vitamin D on the Immune System and Autoimmune Diseases

International Journal of Molecular Sciences, 2022
Vitamin D intervenes in calcium and phosphate metabolism and bone homeostasis. Experimental studies have shown that 1,25-dihydroxyvitamin D (calcitriol) generates immunologic activities on the innate and adaptive immune system and endothelial membrane ...
C. Sîrbe, S. Rednic, A. Grama, T. Pop
semanticscholar   +1 more source

Myristoylated, alanine-rich C-kinase substrate (MARCKS) regulates toll-like receptor 4 signaling in macrophages

Scientific Reports, 2023
MARCKS (myristoylated alanine-rich C-kinase substrate) is a membrane-associated protein expressed in many cell types, including macrophages. MARCKS is functionally implicated in cell adhesion, phagocytosis, and inflammation.
Jiraphorn Issara-Amphorn, Virginie H. Sjoelund, Margery Smelkinson, Sebastian Montalvo, Sung Hwan Yoon, Nathan P. Manes, Aleksandra Nita-Lazar   +6 more
doaj   +1 more source

The interaction between nanoparticles and immune system: application in the treatment of inflammatory diseases

Journal of Nanobiotechnology, 2022
Nanoparticle (NP) is an emerging tool applied in the biomedical field. With combination of different materials and adjustment of their physical and chemical properties, nanoparticles can have diverse effects on the organism and may change the treating ...
Jin Liu, Zeyang Liu, Yan Pang, Huifang Zhou   +3 more
semanticscholar   +1 more source

The Effects of Vitamin D on Immune System and Inflammatory Diseases

Biomolecules, 2021
Immune cells, including dendritic cells, macrophages, and T and B cells, express the vitamin D receptor and 1α-hydroxylase. In vitro studies have shown that 1,25-dihydroxyvitamin D, the active form of vitamin D, has an anti-inflammatory effect.
Tomoka Ao, J. Kikuta, M. Ishii
semanticscholar   +1 more source