Results 11 to 20 of about 20,768,159 (307)
Biology Bulletin Reviews, 2022 This review presents, in detail and from multiple angles, the classification of diseases of the immune system during different periods of a person’s life, including immune-associated and immune-dependent diseases, their phenomenology, disease triggers, and the mechanisms of regulation of immune reactivity.
Maria Kozlova +2 more
exaly +2 more sources
Small and Long Regulatory RNAs in the Immune System and Immune Diseases [PDF]
Frontiers in Immunology, 2014 Cellular differentiation is regulated on the level of gene expression, and it is known that dysregulation of gene expression can lead to deficiencies in differentiation that contribute to a variety of diseases, particularly of the immune system. Until recently, it was thought that the dysregulation was governed by changes in the binding or activity of ...
Sebo Withoff, Maria M Zorro
exaly +4 more sources
Treatment update for autoimmune/immune-mediated central nervous system diseases
Folia NeuropathologicaAutoimmune/immune-mediated central nervous system (CNS) diseases are chronic, inflammatory, autoimmune diseases, such as multiple sclerosis (MS), neuromyelitis optica spectrum disorder (NMOSD), and autoimmune encephalitis (AE).
Jiayi Wu +5 more
doaj +2 more sources
Immune System and Chronic Diseases [PDF]
Journal of Immunology Research, 2017 Margarete Dulce Bagatini +3 more
doaj +3 more sources
SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain
Communications Biology, 2023 The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions.
Jiansheng Jiang +6 more
doaj +1 more source
The Immune System of Marine Organisms as Source for Drugs against Infectious Diseases [PDF]
, 2022 The high proliferation of microorganisms in aquatic environments has allowed their coevolution for billions of years with other living beings that also inhabit these niches.
core +1 more source
Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways
Scientific Data, 2022 Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes +6 more
doaj +1 more source
Scientific Reports, 2023 MARCKS (myristoylated alanine-rich C-kinase substrate) is a membrane-associated protein expressed in many cell types, including macrophages. MARCKS is functionally implicated in cell adhesion, phagocytosis, and inflammation.
Jiraphorn Issara-Amphorn +6 more
doaj +1 more source
Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation
Nature Communications, 2022 The catalytic chaperone tapasin assists peptide loading onto MHC-I molecules for antigen presentation and immune recognition. Here, the authors present crystal structures that provide insights into the molecular mechanism of tapasin-mediated peptide ...
Jiansheng Jiang +11 more
doaj +1 more source
The Innate Immune System in Alzheimer’s Disease [PDF]
International Journal of Cell Biology, 2013 Alzheimer’s disease (AD) is the leading cause for dementia in the world. It is characterized by two biochemically distinct types of protein aggregates: amyloidβ(Aβ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (CAA) and aggregated tau protein in the form of intraneuronal neurofibrillary tangles (NFT).
Allal Boutajangout, Thomas Wisniewski
openaire +3 more sources