Results 11 to 20 of about 1,192,654 (265)
Biology Bulletin Reviews, 2022 This review presents, in detail and from multiple angles, the classification of diseases of the immune system during different periods of a person’s life, including immune-associated and immune-dependent diseases, their phenomenology, disease triggers, and the mechanisms of regulation of immune reactivity.
A M Zemskov, V A Zemskova, M N Kozlova
exaly +2 more sources
Glucocorticoid use as a cause of non-cellular immune response to SARS-Cov2 Spike in patients with immune system diseases. [PDF]
J Autoimmun, 2022 Renaudineau Y +10 more
europepmc +2 more sources
Immune System and Chronic Diseases [PDF]
Journal of Immunology Research, 2017 Margarete Dulce Bagatini +3 more
openaire +3 more sources
SARS-CoV-2 antibodies recognize 23 distinct epitopic sites on the receptor binding domain
Communications Biology, 2023 The COVID-19 pandemic and SARS-CoV-2 variants have dramatically illustrated the need for a better understanding of antigen (epitope)-antibody (paratope) interactions.
Jiansheng Jiang +6 more
doaj +1 more source
Absolute protein quantitation of the mouse macrophage Toll-like receptor and chemotaxis pathways
Scientific Data, 2022 Measurement(s) molecules per cell Technology Type(s) nanoflow high-performance liquid chromatography-electrospray ionisation tandem mass spectrometry Sample Characteristic - Organism Mus ...
Nathan P. Manes +6 more
doaj +1 more source
Scientific Reports, 2023 MARCKS (myristoylated alanine-rich C-kinase substrate) is a membrane-associated protein expressed in many cell types, including macrophages. MARCKS is functionally implicated in cell adhesion, phagocytosis, and inflammation.
Jiraphorn Issara-Amphorn +6 more
doaj +1 more source
The Innate Immune System in Alzheimer’s Disease [PDF]
International Journal of Cell Biology, 2013 Alzheimer’s disease (AD) is the leading cause for dementia in the world. It is characterized by two biochemically distinct types of protein aggregates: amyloidβ(Aβ) peptide in the forms of parenchymal amyloid plaques and congophilic amyloid angiopathy (CAA) and aggregated tau protein in the form of intraneuronal neurofibrillary tangles (NFT).
Allal Boutajangout, Thomas Wisniewski
openaire +3 more sources
Structural mechanism of tapasin-mediated MHC-I peptide loading in antigen presentation
Nature Communications, 2022 The catalytic chaperone tapasin assists peptide loading onto MHC-I molecules for antigen presentation and immune recognition. Here, the authors present crystal structures that provide insights into the molecular mechanism of tapasin-mediated peptide ...
Jiansheng Jiang +11 more
doaj +1 more source
The Role of the Immune System in Huntington’s Disease [PDF]
Clinical and Developmental Immunology, 2013 Huntington’s disease (HD) is characterized by a progressive course of disease until death 15–20 years after the first symptoms occur and is caused by a mutation with expanded CAG repeats in the huntingtin (htt) protein. Mutant htt (mhtt) in the striatum is assumed to be the main reason for neurodegeneration.
Gisa Ellrichmann +3 more
openaire +3 more sources
Cell Reports, 2022 Summary: Biologically active small molecules can impart modulatory effects, in some cases providing extended long-term memory. In a screen of biologically active small molecules for regulators of tumor necrosis factor (TNF) induction, we identify several
Sinu P. John +13 more
doaj +1 more source