Results 191 to 200 of about 198,891 (298)

Efficacy and Safety of Intralymphatic Immunotherapy With Grass Allergoid and Microcrystalline Tyrosine: A Double‐Blind Randomised Placebo‐Controlled Trial

open access: yesAllergy, EarlyView.
This is the first randomised placebo‐controlled trial of intralymphatic immunotherapy using a microcrystalline tyrosine‐adjuvanted grass pollen allergoid. Three ultrasound‐guided ILIT injections were well tolerated and reduced combined symptom‐medication scores compared with placebo. The findings support further optimisation and clinical development of
Lara Šošić   +13 more
wiley   +1 more source

Serum‐Proteomic Profiling Reveals Distinct Atopic Dermatitis Severity‐Linked Signatures

open access: yesAllergy, EarlyView.
This study aimed to identify a set of serum biomarkers that robustly distinguish prespecified severe from mild atopic dermatitis groups. Serum proteomic profiling distinguishes severe from mild atopic dermatitis, revealing an epithelial enriched severity footprint linked to LDH‐associated tissue injury and Th2/Th22 inflammation.
Jag S. Lally   +6 more
wiley   +1 more source

Influence of Environmental Pollution on Basophil Reactivity to Birch Pollen Allergens in Atopic and Non‐Atopic Subjects

open access: yesAllergy, EarlyView.
Birch pollen and PM10 are key determinants of clinical symptoms, particularly in asthma. Allergic people react stronger to the pollen collected in the highly polluted area than in the less polluted areas. When evaluating the effectiveness of allergen immunotherapy, it is essential to consider not only pollen concentrations but also levels of air ...
Maria Czarnobilska   +5 more
wiley   +1 more source

Local allergic rhinitis

open access: yesBrazilian Journal of Otorhinolaryngology, 2016
openaire   +4 more sources

m6A‐Related Regulation of Ferroptosis Contributes to Nasal Epithelial Barrier Dysfunction in Allergic Rhinitis

open access: yesAllergy, EarlyView.
This study uses human nasal epithelial cells and BALB/c mice to evaluate the role and molecular mechanism of ferroptosis in HDM‐induced AR, focusing on ferroptosis‐related responses and nasal epithelial barrier disruption. HDM exposure induces lipid peroxidation‐driven ferroptosis and epithelial barrier disruption.
Zehua Lin   +9 more
wiley   +1 more source

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