Results 121 to 130 of about 217,585 (300)

Hygiene hypothesis and innate immunity. evaluating the role of environmental factors and genetic polymorphisms on the expression of receptors of the innate immune system [PDF]

open access: yes, 2009
Background In ‘westernised’ countries, the prevalence of childhood asthma and allergy has risen throughout the last few decades. A series of epidemiological studies showed reduced prevalence of asthma and allergy among farmers’ children compared to non ...
Bieli, Christian
core   +1 more source

A review on hypersensitivity reactions to fungal aeroallergens in patients with allergic disorders in Iran

open access: yesCurrent Medical Mycology, 2019
Fungal agents account for the clinical manifestation of allergic disorders. The aim of the present study was to review the prevalence of hypersensitivity reactions to fungal aeroallergens in patients with allergic disorders, including allergic rhinitis ...
zeinab Nazari   +3 more
doaj  

Exposure to house dust endotoxin and allergic sensitization in adults.

open access: yes, 2004
Background:  It has been suggested that exposure to elevated levels of endotoxin decreases the risk of allergic sensitization. Objective:  To examine the associations between current exposure to bacterial endotoxin in house dust and ...
Wichmann, H.-E.   +6 more
core   +1 more source

Symptoms of titanium and nickel allergic sensitization in orthodontic treatment

open access: yes, 2020
The study aimed to evaluate to which extent self-reported symptomatology, age, and sex are predictors of titanium and nickel allergic sensitization in patients in treatment with fixed orthodontic appliances.
Trinajstić Zrinski, Magda   +5 more
core   +1 more source

Metrnβ drives sepsis immunosuppression via macrophage reprogramming: A novel prognostic biomarker and therapeutic target

open access: yesInterdisciplinary Medicine, EarlyView.
Metrnβ serves as a novel prognostic biomarker for sepsis and that targeted blockade of the Metrnβ‐c‐Kit axis represents a promising therapeutic strategy for sepsis. Abstract Sepsis is a heterogeneous syndrome critically driven by immunosuppression, yet lacking personalized prognostic markers and therapeutic targets. Here, we provide evidence to support
Xiao Li   +15 more
wiley   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye   +3 more
wiley   +1 more source

A Practical and Efficient Multiplex qPCR Assay for Simultaneous Detection of HLA Cross‐Reactive Groups and Human Platelet Antigens

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
This assay enables multiplex genotyping of HLA‐CREGs and HPA alleles from whole blood using qPCR with an integrated parallel negative control. Results are interpreted based on amplification curves and Ct values, with validity dependent on strict quality control criteria for both the target reactions and the negative control.
Huimin Ji   +9 more
wiley   +1 more source

Anti‐Erythrocyte Antibody Formation in Individuals With and Without Known Sensitisation Pathways Reflecting Indications for Extended Immunohaematology Screening

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
– The yearly incidence of anti‐red blood cell antibodies stratified by participant groups and temporal evolution. – Overall significance p = 3.756 × 10−29. ABSTRACT Background Blood transfusion therapies are of vital importance for many patient groups.
Milanka Milosavić   +3 more
wiley   +1 more source

Adaptive Immunity in Marsupials

open access: yesJournal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
Comparison of the marsupial and eutherian adaptive immune systems. ABSTRACT Marsupials diverged from eutherian mammals 125–160 million years ago. Although evolutionarily distinct, both groups of mammals can produce complex adaptive immune responses to antigens with several key differences.
Cassandra L. Jol   +2 more
wiley   +1 more source

Secreted phospholipase A2 group X regulates peripheral sensitization to allergen

open access: yesJCI Insight
The molecular mechanisms responsible for the “atopic march” of allergic skin disease to allergic airway disease are incompletely understood.
Ryan C. Murphy   +8 more
doaj   +1 more source

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