Results 141 to 150 of about 217,585 (300)

Molecular sensitization profiles and β-parvalbumin sensitization burden associated with clinical fish allergy in children

Frontiers in Immunology
BackgroundFish allergy is a potentially severe condition that is frequently managed with broad elimination diets. Molecular allergology may improve risk stratification by distinguishing clinically relevant fish allergy from asymptomatic sensitization. We
Sevda Tuten Dal, Lala Heydarova, Bulent Enis Sekerel   +2 more
doaj   +1 more source

Efficacy of Ultrasound‐Guided Intercostal Nerve Block With Liposomal Bupivacaine for Treating Postherpetic Neuralgia in Adult Patients

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT The study aimed to investigate the efficacy of ultrasound‐guided intercostal nerve block (ICNB) with liposomal bupivacaine (LB) comparing ropivacaine‐dexamethasone (RD) for treating postherpetic neuralgia (PHN) in adult patients. A total of 108 patients were randomized 1:1 to receive ICNB with LB or ICNB with RD.
Jin Li, Xiang‐Yu Fang
wiley   +1 more source

Indoor Exposure to Molds and Allergic Sensitization.

, 2002
Evidence that indoor dampness and mold growth are associated with respiratory health has been accumulating, but few studies have been able to examine health risks in relation to measured levels of indoor mold exposure.
Ritz, B., Koch, A., Wichmann, H.-E., Bischof, W., Jacob, B., Gehring, U., Heinrich, J., INGA Study Group ()   +7 more
core  

Mechanism of RNA‐Binding Protein ELAVL1 in Promoting Th2 Cell Differentiation Through Stabilizing CPA3 mRNA in Allergic Rhinitis

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study aimed to elucidate the role of the RNA‐binding protein embryonic lethality abnormal vision‐like protein 1 (ELAVL1) in the pathogenesis of allergic rhinitis (AR), specifically by investigating its potential to promote T helper 2 (Th2) cell differentiation by regulating the stability of carboxypeptidase A3 (CPA3) mRNA.
Meng‐Ya Liu, Hong‐Bing Yao, Cheng Chen   +2 more
wiley   +1 more source

Knowledge Integration in Professional Practices: Towards a New Transacting Approach

Knowledge and Process Management, EarlyView.
ABSTRACT This paper advances understanding of knowledge integration across professional boundaries by examining how professionals coordinate action in two life‐ and time‐critical settings: aircraft maintenance and emergency healthcare. Building on established knowledge integration perspectives, the study investigates situations in which actors must ...
Ann Svensson, Ritva Rosenbäck
wiley   +1 more source

Pregabalin Efficacy in Treatment of Chronic Neurogenic Cough

The Laryngoscope, EarlyView.
The use of neuromodulators for chronic cough has increased; however, the choice of medication, dosing regimen, and duration are still unclear. This longitudinal study of 95 adults taking pregabalin, 75 mg twice daily, for CNC demonstrated 78% improvement or resolution of cough, 17% unchanged, 1% worse cough, with a mean of 6 weeks of therapy, and only ...
Jacqui Allen, Carmen Esna, Camille Prigent, Anna Miles   +3 more
wiley   +1 more source

Supraglottic Botulinum Toxin Injection Improves Symptoms of Laryngeal Sensory Dysfunction

The Laryngoscope, EarlyView.
In this retrospective cohort of 80 patients with refractory laryngeal sensory symptoms, supraglottic botulinum toxin type A significantly improved Laryngeal Hypersensitivity Questionnaire, Reflux Symptom Index, and Cough Severity Index scores at a mean of 5.2 weeks, while Voice Handicap Index‐10 scores remained unchanged.
Daniel Novakovic, Katrina Sandham, Thomas Emslie Stewart, James Jordan Johnston   +3 more
wiley   +1 more source

KAT8‐Low Osteosarcoma Suppresses Cisplatin Sensitivity via H4K16ac‐Mediated Cell Apoptosis

Med Research, EarlyView.
The scientific significance of this study is highlighted below: (1) Data mining and clinical discovery: These findings establish a direct clinical link between the KAT8–H4K16ac axis and chemotherapy response in osteosarcoma. (2) Multi‐omics and machine‐learning integration: We integrated proteomics and CUT&Tag multi‐omics to elucidate how chromatin ...
Zhenqun Zhao, Guohui Yu, Shikui Wu, Zhiyang Zhang, Keke Wang, Yingxin Xiong, Chao Sun, Haobo Cui, Yuxing Wang, Ziheng Wang, Huiru Zhang, Huiqin Xue, Shibing Guo   +12 more
wiley   +1 more source

Exposure to house dust endotoxin and allergic sensitization in allergic and nonallergic children living in Adana, Turkey

The Turkish Journal of Pediatrics, 2009
It has been suggested that exposure to elevated levels of endotoxin decreases the risk of allergic sensitization. The objective of our study was to analyze associations between house dust endotoxin levels and allergic sensitization in children ...
Mustafa Yilmaz, Derya Ufuk Altintaş, Gülbin Bingöl-Karakoç, Ayfer Inal, Mehmet Kiliç, Zeynel Sütolukta, Seval Güneşer-Kendirli   +6 more
doaj  

Glucocorticoids Impair the Airway Epithelial Barrier via Autophagy‐Associated Apoptosis in Asthma: A Preliminary Study Both In Vitro and In Vivo

Pediatric Discovery, EarlyView.
Mechanism underlying the negative effects of glucocorticoids on the airway epithelial barrier. Glucocorticoids upregulate autophagy factors and downregulate anti‐autophagy factors. Enhanced autophagy promotes excessive apoptosis and epithelial detachment, impairing airway barrier function.
Hao You, Wenjing Zou, Tangqiaochu Gan, Yu Zhao, Jie Hu, Wen Tan, Ting Wang, Luo Ren, Zhengxiu Luo, Zhou Fu, Chao Niu   +10 more
wiley   +1 more source