Obesity, allergy and immunology [PDF]
Journal of Allergy and Clinical Immunology, 2005 J ALLERGY CLIN IMMUNOL described an association between obesity and asthma (Fig 2). In a large population of white Australian girls, a higher bodymass indexwas reported to be a risk factor for atopy and wheeze. As a corollary, weight loss, as after bariatric surgery, has consistently been shown to improve asthma severity and control (Fig 3). Changes in
Céline Bergeron, LP Boulet, Q Hamid
openalex +4 more sources
Pruritus in allergy and immunology. [PDF]
J Allergy Clin Immunol, 2019 Although evolutionarily conserved to expel ectoparasites and aid in the clearance of toxins and noxious environmental stimuli from the host, the type 2 immune response can become pathologic in the setting of a variety of allergic disorders. Itch can be a behavioral extension of type 2 immunity by evoking scratching and, in the setting of disease, can ...
Yang TB, Kim BS.
europepmc +5 more sources
Allergy-Immunology Glossary [PDF]
The Egyptian Journal of Pediatric Allergy and Immunology, 2019 Towards a clear designation of some of the terms used in allergology and immunology.
Zeinab El-Sayed, Rasha El-Owaidy
openaire +5 more sources
T-cell recognition is shaped by epitope sequence conservation in the host proteome and microbiome [PDF]
, 2016 Several mechanisms exist to avoid or suppress inflammatory T-cell immune responses that could prove harmful to the host due to targeting self-antigens or commensal microbes.
Bancroft, Tara +8 more
core +2 more sources
Determination of a predictive cleavage motif for eluted major histocompatibility complex class II ligands [PDF]
, 2018 CD4+ T cells have a major role in regulating immune responses. They are activated by recognition of peptides mostly generated from exogenous antigens through the major histocompatibility complex (MHC) class II pathway.
Dhanda, Sandeep Kumar +7 more
core +6 more sources
Toxoplasma gondii peptide ligands open the gate of the HLA class I binding groove [PDF]
, 2016 HLA class I presentation of pathogen-derived peptide ligands is essential for CD8+ T-cell recognition of Toxoplasma gondii infected cells. Currently, little data exist pertaining to peptides that are presented after T. gondii infection.
Battle +49 more
core +3 more sources
Automated benchmarking of peptide-MHC class I binding predictions [PDF]
, 2015 Motivation: Numerous in silico methods predicting peptide binding to major histocompatibility complex (MHC) class I molecules have been developed over the last decades. However, the multitude of available prediction tools makes it non-trivial for the end-
Greenbaum, Jason +8 more
core +3 more sources
The Length Distribution of Class I-Restricted T Cell Epitopes Is Determined by Both Peptide Supply and MHC Allele-Specific Binding Preference [PDF]
, 2016 HLA class I-binding predictions are widely used to identify candidate peptide targets of human CD8+ T cell responses. Many such approaches focus exclusively on a limited range of peptide lengths, typically 9 aa and sometimes 9-10 aa, despite multiple ...
Bardet, Wilfried +9 more
core +1 more source
Predictors of allergen sensitization in Singapore children from birth to 3 years [PDF]
, 2016 10.1186/s13223-016-0161-xAllergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology121Article number 56GUSTO (Growing up towards Healthy ...
A. Goh +13 more
core +2 more sources
Monocyte phenotypes: when local education counts [PDF]
, 2015 Monocytes are a heterogeneous population of phagocytic cells that are generated in the bone marrow and released into the bloodstream. There are two main monocyte subsets in mice: “inflammatory” monocytes that are Ly6Chi CCR2hi CX3 CR1low and “alternative”
Amado A. Quintar +3 more
core +1 more source