Results 131 to 140 of about 2,550 (172)
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Frequency of alloantibodies accompanying autoantibodies
Transfusion, 1985Blood samples of 109 patients with warm autoantibodies were evaluated for the presence of accompanying alloantibody. Clinically significant alloantibodies were present in 41, or 38 percent, of the cases.
M L, Laine, K M, Beattie
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Alloantibody production by nude mice
Cellular Immunology, 1980Abstract Nude mice which have been injected with allogeneic cells are able to make cytotoxic antibodies. These antibodies are predominantly IgM and can be detected with rabbit complement but not with guinea pig complement or by hemagglutination. Antibody may be directed against H-2 determinants but antibody against non-H-2 antigens may also be found ...
B, Kindred, V, Schirrmacher
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Alloantibody-Induced Cytotoxicity of Macrophages
The Journal of Immunology, 1975Abstract Alloantibodies substantially alter the in vitro nonspecific cytotoxic effect of macrophages on bystanding allogeneic and xenogeneic target cells. Although the specific IgM alloantibody increased significantly the ability of parental macrophages to damage target cells, IgG alloantibody had an opposite effect and suppressed the ...
Ptak, W, Hanczakowska, M
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THE SPECIFICITY OF IMMUNOSUPPRESSION BY ALLOANTIBODY IN THE MOUSE
Transplantation, 1976The ability of alloantibody to suppress the humoral immune response to transplantation antigens in the mouse has been studied in relation to its specificity. It was found that antibody was able to suppress the cytotoxic antibody response to determinants other than those against which it was directed when there was some common antigenicity between the ...
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The Patient With Multiple Alloantibodies
JAMA: The Journal of the American Medical Association, 1982To the Editor.— A recent report by Patten and Conti inThe Journal(1982;247:209) described collection of 10 units of blood in a 17-week period from a woman who was said to be the only compatible donor for the patient, her sister. The data given leave doubts as to whether the heroic efforts on the part of the donor were really necessary.
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The Journal of Immunology, 1982
Abstract We determined the location of alloantibody formation in the allogeneically pregnant rat. Greater than 95% of the alloantibody-forming cells were found in the spleen. A few were found in the paraaortic, renal, and parathymic lymph nodes. None were found in other lymphomyeloid organs.
R N, Smith, M, Sternlicht
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Abstract We determined the location of alloantibody formation in the allogeneically pregnant rat. Greater than 95% of the alloantibody-forming cells were found in the spleen. A few were found in the paraaortic, renal, and parathymic lymph nodes. None were found in other lymphomyeloid organs.
R N, Smith, M, Sternlicht
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Elucidation of Alloantibodies in Autoimmune Haemolytic Anaemia
Vox Sanguinis, 1988Abstract. Forty‐one patients with autoimmune haemolytic anaemia (AIHA), who had free antibody in their sera, were investigated for the presence of alloimmune erythrocyte antibodies using the ZZAP autoabsorption technique. Patients were subdivided into three risk categories: (I) no prior pregnancy or transfusion; (II) history of pregnancy and/or one to
P, James, G P, Rowe, G G, Tozzo
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Autoantibodies, alloantibodies and reproductive success
Current Opinion in Immunology, 1990It is only since the recognition of rhesus haemolytic disease that the importance of the maternal immune response to fetal antigens has been widely appreciated. The discovety that rhesus isoimmunization can be prevented by an antibody directed against the rhesus D antigen on fetal red cells was an extremely important step forward, as it showed that the
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Immunoglobulin Class Heterogeneity of Platelet Alloantibodies
Vox Sanguinis, 1984Abstract. The immunoglobulin classes of platelet alloantibodies were studied using monospecific antisera in a radiolabeled technique. 14 of 28 consecutively studied multiply transfused oncology patients demonstrated platelet antibodies. These 14 patients were also refractory to random donor platelets.
K, Miller +3 more
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The detection of platelet alloantibodies by flow cytometry
Transfusion, 1991A flow cytometric procedure was investigated for its ability to detect antibodies directed against blood group A, HLA, and PlA1 (HPA‐1a) antigens. When type O sera were tested against platelets from blood group A donors, only 9 of 14 positive reactions were observed.
L A, Worfolk, B R, MacPherson
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