Results 1 to 10 of about 11,879 (188)

The Rh blood group system and its role in alloimmunization rate among sickle cell disease and sickle thalassemia patients in Iran

Molecular Genetics & Genomic Medicine, 2021
Introduction The alloimmunization following blood transfusion can be life‐threatening. The Rh alloantibodies are one of the most common causes contributing to alloimmunization.
Mohammad Ali Jalali Far, Arezoo Oodi, Naser Amirizadeh   +2 more
exaly   +3 more sources

Red Blood Cell Alloimmunization and Autoimmunization in Blood Transfusion-Dependent Sickle Cell Disease and β-Thalassemia Patients in Al-Ahsa Region, Saudi Arabia

Anemia, 2023
Introduction. The risk of developing transfusion-related complications, especially alloimmunization, is an ongoing concern for transfusion-dependent patients.
Fahd A. Kuriri, Abdulrahman Ahmed, Fehaid Alanazi, Fahad Alhumud, Mohammed Ageeli Hakami, Osama Atiatalla Babiker Ahmed   +5 more
doaj   +2 more sources

FcγRIV is required for IgG2c mediated enhancement of RBC alloimmunization

Frontiers in Immunology, 2022
Passive immunization with anti-D can prevent maternal alloimmunization to RhD thereby preventing hemolytic disease of the fetus and newborn. Unexpectedly, anti-D fails in some cases and some monoclonal anti-D preparations paradoxically enhances ...
Annie Qiu, Anabel Miller, Flavia Dei Zotti, Manjula Santhanakrishnan, Jeanne E. Hendrickson, Maria Tredicine, Sean R. Stowell, Chance John Luckey, James C. Zimring, James C. Zimring, Krystalyn E. Hudson   +10 more
doaj   +2 more sources

Reticulocytes in donor blood units enhance red blood cell alloimmunization

Haematologica, 2023
Although red blood cell (RBC) transfusions save lives, some patients develop clinically-significant alloantibodies against donor blood group antigens, which then have adverse effects in multiple clinical settings. Few effective measures exist to prevent
Tiffany A. Thomas, Annie Qiu, Christopher Y. Kim, Dominique E. Gordy, Anabel Miller, Maria Tredicine, Monika Dzieciatkowska, Flavia Dei Zotti, Eldad A. Hod, Angelo D’Alessandro, James C. Zimring, Steven L. Spitalnik, Krystalyn E. Hudson   +12 more
doaj   +2 more sources

Type I interferon signature strength correlates with alloimmunization-associated transcriptomic programs in systemic lupus erythematosus: A multi-cohort analysis. [PDF]

PLoS ONE
Red blood cell (RBC) alloimmunization is a clinically significant complication in transfused patients whose immunological determinants remain incompletely understood.
Jaeeun Yoo
doaj   +2 more sources

Back to base pairs: What is the genetic risk for red bloodcell alloimmunization?

Blood Reviews, 2021
Red blood cell (RBC) alloimmunization is a serious complication of blood transfusions, challenging selection of compatible units for future transfusions.
Bart J Biemond, C E van der Schoot
exaly   +2 more sources

Red Cell Alloimmunization and Autoimmunization Among Sickle Cell Disease and Thalassemia Patients in Jazan Province, Saudi Arabia

International Journal of General Medicine, 2022
Amr J Halawani,1 Abdullah A Mobarki,2 Ali H Arjan,3 Muhammad Saboor,2 Hassan A Hamali,2 Gasim Dobie,2 Khalaf F Alsharif4 1Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia; 2Department of
Halawani AJ, Mobarki AA, Arjan AH, Saboor M, Hamali HA, Dobie G, Alsharif KF   +6 more
doaj   +2 more sources

RBC Alloimmunization in Sudanese Multi-transfused Patients [PDF]

Journal of Bioscience and Applied Research, 2020
Background: Blood transfusions are a life-saving measure to replace blood lost through severe bleeding or as a life-saving treatment for various hematological conditions. Blood transfusions are high-risk procedures. One of these risks is alloimmunization.
Hager Elkobani, Sahar Elbager, Magdi Bayoumi   +2 more
doaj   +1 more source

Not as “D”eadly as once thought – the risk of D-alloimmunization and hemolytic disease of the fetus and newborn following RhD-positive transfusion in trauma

Hematology, 2023
The use of blood products to resuscitate injured and massively bleeding patients in the prehospital and early in-hospital phase of the resuscitation is increasing.
M. Yazer, G. Panko, J. Holcomb, Alesia Kaplan, C. Leeper, J. Seheult, D. Triulzi, P. Spinella   +7 more
semanticscholar   +1 more source

Alloimmunization and hyperhemolysis in sickle cell disease.

Hematology. American Society of Hematology. Education Program, 2023
Alloimmunization against red blood cell antigens and delayed hemolytic transfusion reaction (DHTR) are major barriers to transfusion in sickle cell disease (SCD). In SCD, DHTR is a potentially life-threatening.
F. Pirenne, C. Pondarré
semanticscholar   +1 more source